Patents by Inventor Francesc Rabanal Anglada

Francesc Rabanal Anglada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210253520
    Abstract: It relates to polymyxin analogues having a disulfide bond and an amino alcohol group adjacent to the disulfide bond, and optionally, an ester bond in the peptide backbone, which are useful as antibacterial agent, as well as to pharmaceutical compositions comprising them. It also relates to a key intermediate compound of formula (II) and its preparation process.
    Type: Application
    Filed: March 17, 2021
    Publication date: August 19, 2021
    Inventor: Francesc RABANAL ANGLADA
  • Publication number: 20130053305
    Abstract: Compounds of formula (I), where: R0 is (C8-C11)-branched alkyl, CH3—(CH2)m—, CH3—O—(CH2CH2O)2CH2—, or phenyl-(CH2)x—; m=6-10; x=1-3; R1, R3, R4, R7, and R8 are independently selected from the formula GF-(CH2)n—; with n=1-4; and GF=—NH2 or —NH—C(?NH)—NH2; R2 is —CH(CH3)(OH), —CH(CH3)2, —CH2NH2 o —CH2OH; R5 and R6 are independently selected among H, —(C1-C4)— linear or branched alkyl, —(CH2)—R10, —CH2—CH2—S—CH3 and —CH—(CH3)—OH; R9 is CONH2, —CH(CH3)(OH) or CONHR11; R10 is phenyl, 3-indolyl, 4-imidazolyl, 4-hydroyiphenyl, ? o ?-naphtyl or 2-, 3- or 4-pyridyl; R11 is a specific peptide sequence; u is CH2 or S; v is NH o S; w is CH2 or CO; with the condition that when R9 is CONH2, then (a) R5 or R6 is —CH(CH3)(OH), or (b) R5 and R6 are H; or (c) the configuration of the C bound to R9 is S or (d) the configuration of the C bound to R5 is R; and with the condition that when R9 is —CH(CH3)OH, then R8 is GF(CH2)n where n is 3 and GF is —NH—C(?NH)—NH2, and R7 is GF(CH2)n where n is 2 and GF is NH2, have been found to
    Type: Application
    Filed: March 9, 2011
    Publication date: February 28, 2013
    Applicant: UNIVERSIDAD DE BARCELONA
    Inventors: Francesc Rabanal Anglada, Yolanda Cajal Visa, Maria Garcia Subirats, Montserrat Rodrígues Núñez
  • Publication number: 20050276783
    Abstract: The present application relates to new peptide polymers comprising monomeric units derived from the residues of glutamic acid, aspartic acid and lysine, or their protected derivatives, and which are functionalized through the introduction of side chains containing thiol groups or protected thiol groups. The new peptide polymers can be crosslinked in aqueous medium, and the resulting polymer matrices have the capacity to entrap drugs and, subsequently, release them in a controlled way when introduced into a physiological medium. This enables new pharmaceutical compositions to be developed for the controlled release of drugs, especially peptide- and protein-based ones.
    Type: Application
    Filed: June 8, 2005
    Publication date: December 15, 2005
    Inventors: Ernest Giralt Lledo, Pau Cid Poyatos, Jose Pastor Porras, Oscar Pena Gulin, Francesc Rabanal Anglada