Patents by Inventor Frank Chisari

Frank Chisari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Proteinaceous antigens with conformation-independent and conformation-dependent determinants
    Patent number: 4683136
    Abstract: A single polypeptide antigen that includes the amino acid residue sequence and epitope of a conformation-independent antigenic determinant and the amino acid residue sequence but lacks the epitope of a conformation-dependent antigenic determinant is disclosed as are methods of its manufacture and use and articles of manufacture using the same. The uses of the pre-S(2) region polypeptide encoded by the hepatitis B virus genome as a T cell proliferating agent and as a potentiator for enhancing the humoral immune response of animals that exhibit a low humoral response to an S region-containing immunogen are also disclosed.
    Type: Grant
    Filed: March 6, 1985
    Date of Patent: July 28, 1987
    Assignee: Scripps Clinic and Research Foundation
    Inventors: David Milich, Frank Chisari