Abstract: A food intake-limiting device for peroral implantation in the stomach adjacent a gastroesophageal junction is disclosed. The device can have an inner basket nested in an outer basket, a proximal entry opening and a distal exit opening to limit a rate of efflux, mesh openings in the outer basket for protrusion of stomach lining into the outer basket, and a plurality of spikes mounted tangentially on the inner basket for transfixing the protruding stomach lining. The inner basket is rotatable with respect to the outer basket to effect the transfixation. Also disclosed are an implantation/extraction tool, and methods for implanting and removing the device in a patient in need of obesity treatment.

Abstract: Disclosed are esophageal anti-reflux valve prostheses, and tools and procedures for peroral implantation and extraction of the prostheses. The prostheses disclosed have a semipermeable membrane to allow retrograde passage of gas, magnets disposed at a distal end of the sleeve to facilitate closure, and an outwardly bendable array of spikes that are longitudinally aligned for peroral insertion and lockable into a radially outwardly deployed configuration to keep the prosthesis from dislocating implantation. The implantation tool has inner and outer concentric tubes, the inner tube releasably threadably connected to the prosthesis, the outer tube reverse threaded with the inner tube to advance a distal headpiece to engage, deploy and lock the spikes into the deployed configuration. A vacuum assist can be used to help impact the lumen wall on the spikes.

Abstract: A food intake-limiting device for peroral implantation in the stomach adjacent a gastroesophageal junction is disclosed. The device can have an inner basket nested in an outer basket, a proximal entry opening and a distal exit opening to limit a rate of efflux, mesh openings in the outer basket for protrusion of stomach lining into the outer basket, and a plurality of spikes mounted tangentially on the inner basket for transfixing the protruding stomach lining. The inner basket is rotatable with respect to the outer basket to effect the transfixation. Also disclosed are an implantation/extraction tool, and methods for implanting and removing the device in a patient in need of obesity treatment.

Abstract: Methods and apparatus for making self-supporting bodies from particulate materials. The apparatus includes a mold with opposed first and second walls defining a particulate chamber therebetween. The second wall is advanceable and retractable toward and away from the first wall. A plurality of chamber reducers may be removably mounted over each of the walls. Thick-walled members can be incrementally built up by pressing successive batches of particulate material at low and high pressures respectively. The chamber reducers can be successively removed between such batches, or can be used to vary the mold for making bodies of different sizes. A long body can be built up in increments, using a shorter mold, by forming a first increment, displacing the increment lengthwise in the mold, adding another batch of particulate material in overlapping relation to the first body increment, and then pressing such other batch to form a second increment bonded to the first.

Abstract: A check valve in which one half of the valve body has a number of integral guide fins extending radially into the flowway. The guide fins are discontinuous from one another at their radially inner ends. A liner on the interior of the valve body follows the contour of the guide fins so that the portions of the liner which cover respective guide fins are likewise discontinuous from one another at their radially inner ends. The thermal properties of the liner differ from those of the guide fins. Each of the guide fins has a transverse bore through which extends an anchoring plug, the plug in turn interconnecting portions of the liner on opposite sides of the guide fins. A valve element longitudinally reciprocable in the flowway includes a closure portion for engagement with a valve seat and an elongate valve stem extending longitudinally from the closure portion and surrounded by and slidably engaged with the lined inner ends of the guide fins.

Abstract: The invention pertains to the manufacture of articles of thermosetting plastics and other materials. In a first stage, a solid article is formed from a particulate material by introducing such material into a first chamber defined partially by the backing surface of a backing member and partially by the opposed pressing surface of a pressing member. The backing member is frangible and is removably mounted on a support. The first chamber is then closed and the pressing member advanced toward the backing surface to contract the first chamber and compress the particulate material between the pressing and backing surfaces to form the solid article. The pressing member is then retracted, the first chamber is opened, and the backing member and solid article are removed from the support as a unit. Finally, the backing member is fractured and the fragments are removed from the solid article. In a second stage, the convoluted article, or any other similar body is supported in a chamber structure.

Abstract: An expandable member is disclosed that includes a molded body of elastomeric material with a core embedded therein. At least a portion of the core is not bonded to the body. A fluid conduit is provided through which fluid can be injected between the core and the unattached portion of the body to move the core and the unattached portion apart and expand the member.

Abstract: The invention pertains to the manufacture of articles of thermosetting plastics and other materials. In a first stage, a solid article is formed from a particulate material by introducing such material into a first chamber defined partially by the backing surface of a backing member and partially by the opposed pressing surface of a pressing member. The backing member is frangible and is removably mounted on a support. The first chamber is then closed and the pressing member advanced toward the backing surface to contract the first chamber and compress the particulate material between the pressing and backing surfaces to form the solid article. The pressing member is then retracted, the first chamber is opened, and the backing member and solid article are removed from the support as a unit. Finally, the backing member is fractured and the fragments are removed from the solid article. In a second stage, the convoluted article, or any other similar body is supported in a chamber structure.

Abstract: An expandable member is disclosed that includes a molded body of elastomeric material with a core embedded therein. At least a portion of the core is not bonded to the body. A fluid conduit is provided through which fluid can be injected between the core and the unattached portion of the body to move the core and the unattached portion apart and expand the member.

Abstract: The invention pertains to the manufacture of articles of thermosetting plastics and other materials. In a first stage, a solid article is formed from a particulate material by introducing such material into a first chamber defined partially by the backing surface of a backing member and partially by the opposed pressing surface of a pressing member. The backing member is frangible and is removably mounted on a support. The first chamber is then closed and the pressing member advanced toward the backing surface to contract the first chamber and compress the particulate material between the pressing and backing surfaces to form the solid article. The pressing member is then retracted, the first chamber is opened, and the backing member and solid article are removed from the support as a unit. Finally, the backing member is fractured and the fragments are removed from the solid article. In a second stage, the convoluted article, or any other similar body is supported in a chamber structure.