Abstract: Near-to-eye displays support a range of applications from helping users with low vision through augmenting a real world view to displaying virtual environments. The images displayed may contain text to be read by the user. It would be beneficial to provide users with text enhancements to improve its readability and legibility, as measured through improved reading speed and/or comprehension. Such enhancements can provide benefits to both visually impaired and non-visually impaired users where legibility may be reduced by external factors as well as by visual dysfunction(s) of the user. Methodologies and system enhancements that augment text to be viewed by an individual, whatever the source of the image, are provided in order to aid the individual in poor viewing conditions and/or to overcome physiological or psychological visual defects affecting the individual or to simply improve the quality of the reading experience for the user.

Abstract: The present disclosure relates to compounds that act as protein kinase inhibitors, and the synthesis of the same. Further, the present disclosure teaches the utilization of such compounds in a treatment for proliferative diseases, including cancer, particularly breast cancer, and especially ER+ and/or HER2+ breast cancer.

Abstract: The majority of applications for head mounted display (HMD) users, irrespective of whether they are for short-term, long-term, low vision, augmented reality, etc. yield a conflicting set of tradeoffs between user comfort and minimal fatigue and strain during use, ease of attachment, minimizing intrusiveness and aesthetics which must be concurrently balanced with and are often in conflict with providing an optical vision system that provides the user with a wide field of view and high image resolution whilst also offering a large exit pupil for eye placement with sufficient eye clearance. Further, individual users' needs vary as do their needs with the general task at-hand, visual focus, and various regions-of-interest within their field of view. To address these issues, it is necessary to provide a high performance optical system, eyepiece design, and system features which overcome these limitations.

Abstract: Near-to-eye displays within head mounted devices offer both users with and without visual impairments enhanced visual experiences either by improving or augmenting their visual perception. Unless the user directly views the display without intermediate optical elements then the designer must consider chromatic as well as other aberrations. Within the prior art the optical train is either complex through additional corrective elements adding to weight, cost, and size or through image processing. However, real time applications with mobile users require low latency to avoid physical side effects. Accordingly, it would be beneficial to provide near-to-eye displays mitigating these distortions and chromatic aberrations through pre-distortion based electronic processing techniques in conjunction with design optimization of the optical train with low weight, low volume, low complexity, and low cost.

Abstract: Near-to-eye displays within head mounted devices offer both users with and without visual impairments enhanced visual experiences either by improving or augmenting their visual perception. Unless the user directly views the display without intermediate optical elements then the designer must consider chromatic as well as other aberrations. Within the prior art the optical train is either complex through additional corrective elements adding to weight, cost, and size or through image processing. However, real time applications with mobile users require low latency to avoid physical side effects. Accordingly, it would be beneficial to provide near-to-eye displays mitigating these distortions and chromatic aberrations through pre-distortion based electronic processing techniques in conjunction with design optimization of the optical train with low weight, low volume, low complexity, and low cost.

Abstract: Near-to-eye displays within head mounted devices offer both users with and without visual impairments enhanced visual experiences either by improving or augmenting their visual perception. Unless the user directly views the display without intermediate optical elements then the designer must consider chromatic as well as other aberrations. Within the prior art the optical train is either complex through additional corrective elements adding to weight, cost, and size or through image processing. However, real time applications with mobile users require low latency to avoid physical side effects. Accordingly, it would be beneficial to provide near-to-eye displays mitigating these distortions and chromatic aberrations through pre-distortion based electronic processing techniques in conjunction with design optimization of the optical train with low weight, low volume, low complexity, and low cost.

Abstract: Methods, apparatus, and systems for performing an ophthalmic diagnostic test are disclosed. In one aspect, a head-wearable device for administering an ophthalmic test to a subject can comprise a head-wearable frame for mounting the device onto the subject's head, and a light seal configured for coupling to the frame so as to isolate at least one eye of the subject from ambient light when the device is worn by the subject.

Abstract: Methods, apparatus, and systems for performing an ophthalmic diagnostic test are disclosed. In one aspect, a head-wearable device for administering an ophthalmic test to a subject can comprise a head-wearable frame for mounting the device onto the subject's head, and a light seal configured for coupling to the frame so as to isolate at least one eye of the subject from ambient light when the device is worn by the subject.

Abstract: Methods, apparatus, and systems for performing an ophthalmic diagnostic test are disclosed. In one aspect, a head-wearable device for administering an ophthalmic test to a subject can comprise a head-wearable frame for mounting the device onto the subject's head, and a light seal configured for coupling to the frame so as to isolate at least one eye of the subject from ambient light when the device is worn by the subject.

Abstract: Visual impairment, or vision impairment, refers to the vision loss of an individual to such a degree as to require additional support for one or more aspects of their life. Such a significant limitation of visual capability may result from disease, trauma, congenital, and/or degenerative conditions that cannot be corrected by conventional means, such as refractive correction, such as eyeglasses or contact lenses, medication, or surgery. According to embodiments of the invention a method of augmenting a user's sight is provided comprising obtaining an image of a scene using a camera carried by the individual, transmitting the obtained image to a processor, selecting an algorithm of a plurality of spectral, spatial, and temporal image modification algorithms to be applied to the image by the processor, modifying the image using the algorithm substantially in real time, and displaying the modified image on a display device worn by the individual.

Abstract: Within applications for Near-to-Eye (NR2I) displays, irrespective of whether they are for short-term, long-term, low vision, augmented reality, etc., there is a conflicting tradeoff between user comfort, ease of attachment, minimizing intrusiveness and aesthetics which must be concurrently balanced with and are often in conflict with providing an optical vision system within the NR2I display that provides the user with a wide field of view and high image resolution whilst also offering a large exit pupil for eye placement with sufficient eye clearance. Embodiments of the invention address these issues and provide a high performance optical system through the design of the optical eyepiece design to overcome these limitations within a bioptic configuration with laterally disposed displays.

Abstract: For users exploiting near-to-eye (NR2I) displays for augmented reality and/or correction of low vision then the user is typically going to wear the immersive or non-immersive NR2I displays for specific tasks, for specific visual environments, etc. and hence there is an issue of repeatedly attaching and removing the NR2I display. Further, in the majority of applications irrespective of whether for short-term, long-term, low vision, augmented reality, etc. there is a conflicting tradeoff between user comfort, ease of attachment, minimizing intrusiveness and aesthetics. Accordingly, a means of pivotably attaching and supporting a NR2I display is provided wherein the pivotable mounts may be permanently attached, attached, or demountably attached to a frame which may include for some user's prescription lenses.

Abstract: Near-to-eye displays allow a user to be presented with images that are either augmented to address defects or aberrations within their vision or provide additional information. However, an acquired image typically contains content at different depths and absent depth information image processing applied to the acquired image may discount or apply an image modification that reduces visibility of an object. Accordingly, it would be beneficial for such near-to-eye displays to exploit depth information within the image processing and/or generate depth maps allowing images presented to the user to account for depth. It would be further beneficial for such enhancements to be compatible with the evolving low weight, low volume, low complexity, and low cost near-to-eye display systems. It would be further beneficial to provide a user with other non-visual stimuli based upon depth information within the image.

Abstract: A head worn display can be designed with an integrated camera for obtaining an image of a scene, transmitting the obtained image to a processor, modification of the image in substantially real time by the processor, and displaying the modified image on a display device worn by the individual. According to embodiments of the invention various methods are provided for adjusting the position of the displayed video in the horizontal left/right, vertical up/down, and horizontal in/out, and angular up/down dimensions relative to the individual's eyes.

Abstract: Disclosed are methods for developing authorized chemical palettes for formulating products with reduced adverse environmental and/or health concerns, and advising the public to a greater extent regarding the ingredients of products formulated using these palettes. Also disclosed are computer systems to implement such methods.