Abstract: An NMR magnet system uses a Stirling cooler having a cold head that extends into a housing of the system to cool a cold shield surrounding a cryogen vessel. The system may have a damper located between the cooler and the cold shield to reduce a transmission of vibration from the cooler to a magnet coil immersed in the cryogen. The damper may be passive, or may be part of an active damping system that uses an acceleration sensor to drive an active damper that compensates for cooler vibration. A compensation apparatus may use a stored characteristic of a signal distortion caused by the vibration and, in response to a trigger signal from the cooler, apply compensation to an excitation signal provided to a sample by an NMR probe in a bore of the magnet coil, or to an FID signal from the sample that is detected by the probe.

Abstract: An NMR magnet system uses a Stirling cooler having a cold head that extends into a housing of the system to cool a cold shield surrounding a cryogen vessel. The system may have a damper located between the cooler and the cold shield to reduce a transmission of vibration from the cooler to a magnet coil immersed in the cryogen. The damper may be passive, or may be part of an active damping system that uses an acceleration sensor to drive an active damper that compensates for cooler vibration. A compensation apparatus may use a stored characteristic of a signal distortion caused by the vibration and, in response to a trigger signal from the cooler, apply compensation to an excitation signal provided to a sample by an NMR probe in a bore of the magnet coil, or to an FID signal from the sample that is detected by the probe.

Abstract: The ionization chamber consists of a plurality of ports to accept multiple identical devices or varying devices. Ports may be arranged at various positions on the ionization chamber and at various angles with respect to the sampling orifice leading into the vacuum chamber of the mass spectrometer. A plurality of sprayers may operate in a time modulated manner and thereby the simultaneous multiplexed analysis of a multitude of samples is facilitated.

Abstract: A magnet arrangement comprising a superconducting magnet coil system (M) for producing a magnetic field in the direction of a z axis in a working volume (AV) disposed on the z axis about z=0, wherein the superconducting magnet coil system (M) comprises a radially inner partial coil system (C1) and a radially outer partial coil system (C2) which is coaxial thereto, and with a field forming device (P) of magnetic material disposed in a preferably cylindrically symmetrical fashion about the z axis, located radially between the radially inner and the radially outer partial coil system (C1, C2), and being coaxial with respect to the two partial coil systems (C1, C2), wherein the radially inner partial coil system (C1) produces a homogeneous field in the working volume (AV) and the radially outer partial coil system (C2) produces an inhomogeneous field in the working volume (AV) is characterized in that the radially outer partial coil system (C2) produces, together with the magnetic field forming device (P),

Abstract: The ionization chamber consists of a plurality of ports to accept multiple identical devices or varying devices. Ports may be arranged at various positions on the ionization chamber and at various angles with respect to the sampling orifice leading into the vacuum chamber of the mass spectrometer. A plurality of sprayers may operate in a time modulated manner and thereby the simultaneous multiplexed analysis of a multitude of samples is facilitated.

Abstract: The ionization chamber consists of a plurality of ports to accept multiple identical devices or varying devices. Ports may be arranged at various positions on the ionization chamber and at various angles with respect to the sampling orifice leading into the vacuum chamber of the mass spectrometer. A plurality of sprayers may operate in a time modulated manner and thereby the simultaneous multiplexed analysis of a multitude of samples is facilitated.

Abstract: A magnet arrangement comprising a superconducting magnet coil system (M) for producing a magnetic field in the direction of a z axis in a working volume (AV) disposed on the z axis about z=0, wherein the superconducting magnet coil system (M) comprises a radially inner partial coil system (C1) and a radially outer partial coil system (C2) which is coaxial thereto, and with a field forming device (P) of magnetic material disposed in a preferably cylindrically symmetrical fashion about the z axis, located radially between the radially inner and the radially outer partial coil system (C1, C2), and being coaxial with respect to the two partial coil systems (C1, C2), wherein the radially inner partial coil system (C1) produces a homogeneous field in the working volume (AV) and the radially outer partial coil system (C2) produces an inhomogeneous field in the working volume (AV) is characterized in that the radially outer partial coil system (C2) produces, together with the magnetic field forming device (P),

Abstract: In a time-of-flight mass spectrometer with an ion reflector located after the ion source and before the ion detector, to compensate for different starting energies of ions of equal masses, in the ion flight path inside or after the ion reflector at least one electrode is provided for, to which a pulsed high voltage is applied in such a way that within a predetermined narrow range of ion masses, time-of-flight errors for ions of equal masses due to different formation locations or times in the ion source are compensated for at the ion detector. In this way, apart from an energy compensation, also time-of-flight errors of the ions under investigation can simultaneously be compensated for.

Abstract: An RF receiver coil configuration for NMR spectrometers has at least two largely mutually orthogonal RF receiver coil systems of which at least one is made from superconducting material and is at least partially cooled to a cryogenic temperature lying far below room temperature, with each RF receiver coil system comprising at least one single coil arranged symmetrically about a sample the RF receiver coil systems having differing radial separations from the sample. The inner RF receiver coil system is made from a material having differing physical characteristics in dependence on the actual operating temperature than the material of the outer RF receiver coil system, with the materials and the geometries of the RF receiver coil systems being chosen to minimize the influence of the susceptibility of the RF receiver coil system on the homogeneity of the magnetic field in the vicinity of the sample.

Abstract: The invention relates to a device and a method for mass-spectrometric analysis of substance samples which have been separated by capillary electrophoresis, particularly proteins, proteoglycanes or other protein conjugates, with ionization of the substance samples by a particularly substance-saving form of electrospraying. A method of "microspraying" is used which permits a flow of spray liquid of only several tens of nanoliters per minute in stable spray operation. The invention consists in a loose coupling of the spray capillary to the electrophoresis capillary in a liquid environment.