Patents by Inventor Frederic DARIOS

Frederic DARIOS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF GANGLIOSIDES METABOLISM FOR THE TREATMENT OF MOTOR NEURON DISEASES
    Publication number: 20220062254
    Abstract: The present invention relates to inhibitors of gangliosides metabolism for treating motor neuron diseases, in particular hereditary spastic paraplegias.
    Type: Application
    Filed: June 22, 2021
    Publication date: March 3, 2022
    Inventors: Frédéric DARIOS, Giovanni STEVANIN, Fanny MOCHEL, Julien BRANCHU, Maxime BOUTRY
  • Inhibitors of gangliosides metabolism for the treatment of motor neuron diseases
    Patent number: 11065238
    Abstract: The present invention relates to inhibitors of gangliosides metabolism for treating motor neuron diseases, in particular hereditary spastic paraplegias.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: July 20, 2021
    Assignees: ICM (INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE), SORBONNE UNIVERSITE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, APHP (ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS), ÉCOLE PRATIQUE DES HAUTES ÉTUDES
    Inventors: Frédéric Darios, Giovanni Stevanin, Fanny Mochel, Julien Branchu, Maxime Boutry
  • INHIBITORS OF GANGLIOSIDES METABOLISM FOR THE TREATMENT OF MOTOR NEURON DISEASES
    Publication number: 20190350913
    Abstract: The present invention relates to inhibitors of gangliosides metabolism for treating motor neuron diseases, in particular hereditary spastic paraplegias.
    Type: Application
    Filed: November 3, 2017
    Publication date: November 21, 2019
    Inventors: Frédéric DARIOS, Giovanni STEVANIN, Fanny MOCHEL, Julien BRANCHU, Maxime BOUTRY
  • COMPLEXING SYSTEM
    Publication number: 20110038892
    Abstract: The invention relates to a complexing system comprising two polypeptide helices derived from a SNAP protein; one polypeptide helix derived from syntaxin; one polypeptide helix derived from synaptobrevin or a homolog thereof; and one or more cargo moieties attached to the polypeptide helices, wherein the four polypeptide helices can form a stable SNARE complex. The invention also relates to a method of producing the complexing system and the use of the complexing system.
    Type: Application
    Filed: August 11, 2010
    Publication date: February 17, 2011
    Applicants: MEDICAL RESEARCH COUNCIL, ROYAL HOLOLOWAY AND BEDFORD NEW COLLEGE
    Inventors: Bazbek DAVLETOV, Frederic DARIOS, Enrico FERRARI, Mikhail SOLOVIEV