Patents by Inventor Fumiki Harano

Fumiki Harano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9597266
    Abstract: An object of the present invention is to provide a composition for external application that is applied to a part of the skin to more effectively elicit the useful effects of an adenine compound such as adenine, adenosine, and a phosphoric ester of adenosine, and that has long-lasting effects and enhanced skin-moisturizing effects. A gel composition for external application containing an adenine compound such as adenine, adenosine, and a phosphoric ester of adenosine is prepared by using agar as a gelling agent. The gel composition is further prepared in the form of a sheet-like adhesive patch. The gel composition in the form of a sheet-like adhesive patch is kept immersed in an aqueous solution containing the adenine compound.
    Type: Grant
    Filed: August 4, 2008
    Date of Patent: March 21, 2017
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Misato Nakajo, Fumiki Harano, Kosaburo Wakamatsu, Kazuhiro Yagyu
  • Patent number: 9125928
    Abstract: An object of the present invention is to provide an agent for suppressing the formation of skin cells induced by exposure to light such as ultraviolet light. The object is achieved by using a purine nucleic acid for suppressing the formation of abnormal skin cells caused by exposure to light.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: September 8, 2015
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Mitsuaki Kawamura, Shigeo Shinohara, Fumiki Harano, Akihiro Aoki, Eri Ueno
  • Patent number: 9084904
    Abstract: A composition for external use capable of more efficiently deriving the effect of purine substances (and/or salts thereof) including (A) sugar; and (B) at least one member selected from the group consisting of purine substances and salts thereof.
    Type: Grant
    Filed: January 8, 2009
    Date of Patent: July 21, 2015
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Kosaburo Wakamatsu, Shigeo Shinohara, Masahiko Tanaka, Fumiki Harano, Akihiro Aoki, Osamu Takasu
  • Patent number: 8492353
    Abstract: The present invention provides an antiaging composition capable of efficiently retarding skin aging skin aging, particularly, alleviating skin pigmentation. The present invention also provides a method for potentiating the antiaging action of ascorbic acids. The invention provides an antiaging composition containing at least one member selected from the group consisting of ascorbic acid, a derivative of ascorbic acid, and a salt thereof (A), and a purine nucleic acid-related substance (B). The invention provides a method for potentiating the antiaging action of such component (A) by the combined use of at least one member selected from the group consisting of ascorbic acid, a derivative of ascorbic acid, and a salt thereof (A), with a purine nucleic acid-related substance (B).
    Type: Grant
    Filed: August 1, 2003
    Date of Patent: July 23, 2013
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Kosaburo Wakamatsu, Fumiki Harano, Takashige Koba, Shigeo Shinohara
  • Publication number: 20130090301
    Abstract: An object of the present invention is to provide an agent for suppressing the formation of skin cells induced by exposure to light such as ultraviolet light. The object is achieved by using a purine nucleic acid for suppressing the formation of abnormal skin cells caused by exposure to light.
    Type: Application
    Filed: June 24, 2011
    Publication date: April 11, 2013
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Mitsuaki Kawamura, Shigeo Shinohara, Fumiki Harano, Akihiro Aoki, Eri Ueno
  • Patent number: 8409594
    Abstract: The present invention aims to provide solid compositions comprising an oil-in-water emulsion that have sufficient hardness and good feel when used, and can sufficiently exhibit the physiological functions of an electrolyte. A solid composition is obtained by preparing an oil-in-water emulsion by combining a solid oil (A), a liquid oil (B), a surfactant (C), a polyhydric alcohol (D), an electrolyte (E), and water (F).
    Type: Grant
    Filed: December 27, 2005
    Date of Patent: April 2, 2013
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Shigeo Shinohara, Fumiki Harano, Shinji Tsujimoto, Isamu Saeki
  • Publication number: 20110224163
    Abstract: An object of the present invention is to provide a composition for external application that is applied to a part of the skin to more effectively elicit the useful effects of an adenine compound such as adenine, adenosine, and a phosphoric ester of adenosine, and that has long-lasting effects and enhanced skin-moisturizing effects. A gel composition for external application containing an adenine compound such as adenine, adenosine, and a phosphoric ester of adenosine is prepared by using agar as a gelling agent. The gel composition is further prepared in the form of a sheet-like adhesive patch. The gel composition in the form of a sheet-like adhesive patch is kept immersed in an aqueous solution containing the adenine compound.
    Type: Application
    Filed: August 4, 2008
    Publication date: September 15, 2011
    Inventors: Misato Nakajo, Fumiki Harano, Kosaburo Wakamatsu, Kazuhiro Yagyu
  • Patent number: 7994153
    Abstract: The present invention provides a composition that can effectively improve melasma and a composition that can effectively reduce skin dullness. The composition for improving melasma comprises a purine nucleic acid-related substance and a pharmaceutically or cosmetically acceptable carrier, and exhibits an excellent melasma improving effect due to the action of the purine nucleic acid-related substance contained. The composition for reducing skin dullness comprises a purine nucleic acid-related substance and a pharmaceutically or cosmetically acceptable carrier, and exhibits an excellent effect of reducing skin dullness due to the action of the purine nucleic acid-related substance contained.
    Type: Grant
    Filed: May 19, 2003
    Date of Patent: August 9, 2011
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Hideo Tanaka, Masahiko Tanaka, Yasuo Furuta, Kosaburo Wakamatsu, Junko Kamimura, Fumiki Harano, Mitsuaki Kawamura, Shigekatsu Kawabata, Shigeo Shinohara, Noboru Yoshino
  • Publication number: 20100279972
    Abstract: A composition for external use capable of more efficiently deriving the effect of purine substances (and/or salts thereof) including (A) sugar; and (B) at least one member selected from the group consisting of purine substances and salts thereof.
    Type: Application
    Filed: January 8, 2009
    Publication date: November 4, 2010
    Inventors: Kosaburo Wakamatsu, Shigeo Shinohara, Masahiko Tanaka, Fumiki Harano, Akihiro Aoki, Osamu Takasu
  • Patent number: 7820636
    Abstract: An object of the invention is to provide a substance that activates saccharide uptake in epidermal cells and is thus expected to be effective in promoting skin cell neogenesis and metabolism. The invention provides a promoter for saccharide uptake in epidermal keratinocytes which comprises a purine base or a salt thereof as an active ingredient. The present invention further provides a method of promoting saccharide uptake in epidermal keratinocytes, comprising applying a purine base or a salt thereof to the skin.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: October 26, 2010
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Hiromichi Okuda, Chie Morimoto, Kenji Kameda, Fumiki Harano
  • Patent number: 7553101
    Abstract: Provided is a bar-like cosmetic delivering container which is internally sealed and suppresses the cosmetic from forming a play due to negative pressure and prevents the lipstick from contacting the inner surface of a lid sleeve body. The bar-like cosmetic delivering container adapted to project and retract the cosmetic by relative rotation between a receiving sleeve body and an outer sleeve body, wherein a lid sleeve body is provided with a sealing sleeve body adapted to fit on the outer sleeve body, thereby sealing the interior of the container. This ensures that even when the lid sleeve body is opened to release the sealing sleeve body, the receiving sleeve body alone is not internally subjected to negative pressure, preventing the lipstick from floating up or forming a play.
    Type: Grant
    Filed: February 17, 2005
    Date of Patent: June 30, 2009
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Fumiki Harano, Yoshiyuki Murata
  • Publication number: 20080260878
    Abstract: A composition for the prevention or alleviation of pigmentation which can produce the higher effect of preventing or alleviating pigmentation. The composition for the prevention or alleviation of pigmentation comprises a combination of (A) at least one member selected from the group consisting of adenosine 5?-monophosphate and salts thereof with (B) at least one member selected from the group consisting of arbutin, ellagic acid, 4-alkylresorcinols, linoleic acid, tranexamic acid, salts of these, Chamomilla recuita extract, and Ubiquinone.
    Type: Application
    Filed: September 21, 2005
    Publication date: October 23, 2008
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Fumiki Harano, Shigeo Shinohara, Masahiko Tanaka
  • Publication number: 20080095567
    Abstract: Provided is a bar-like cosmetic delivering container which is internally sealed and suppresses the cosmetic from forming a play due to negative pressure and prevents the lipstick from contacting the inner surface of a lid sleeve body. The bar-like cosmetic delivering container adapted to project and retract the cosmetic by relative rotation between a receiving sleeve body and an outer sleeve body, wherein a lid sleeve body is provided with a sealing sleeve body adapted to fit on the outer sleeve body, thereby sealing the interior of the container. This ensures that even when the lid sleeve body is opened to release the sealing sleeve body, the receiving sleeve body alone is not internally subjected to negative pressure, preventing the lipstick from floating up or forming a play.
    Type: Application
    Filed: February 17, 2005
    Publication date: April 24, 2008
    Inventors: Fumiki Harano, Yoshiyuki Murata
  • Publication number: 20070280979
    Abstract: The present invention aims to provide solid compositions comprising an oil-in-water emulsion that have sufficient hardness and good feel when used, and can sufficiently exhibit the physiological functions of an electrolyte. A solid composition is obtained by preparing an oil-in-water emulsion by combining a solid oil (A), a liquid oil (B), a surfactant (C), a polyhydric alcohol (D), an electrolyte (E), and water (F).
    Type: Application
    Filed: December 12, 2005
    Publication date: December 6, 2007
    Inventors: Shigeo Shinohara, Fumiki Harano, Shinji Tsujimoto, Isamu Saeki
  • Publication number: 20050250710
    Abstract: The present invention provides an antiaging composition capable of efficiently retarding skin-aging, particularly, alleviating skin pigmentation. The present invention also provides a method for potentiating the antiaging action of ascorbic acids. The invention provides an antiaging composition containing at least one member selected from the group consisting of ascorbic acid, a derivative of ascorbic acid, and a salt thereof (A), and a purine nucleic acid-related substance (B). The invention provides a method for potentiating the antiaging action of such component (A) by the combined use of at least one member selected from the group consisting of ascorbic acid, a derivative of ascorbic acid, and a salt thereof (A), with a purine nucleic acid-related substance (B).
    Type: Application
    Filed: August 1, 2003
    Publication date: November 10, 2005
    Applicant: KOSABURO WAKAMATSU FUMIKI HARANO
    Inventors: Kosaburo Wakamatsu, Fumiki Harano, Takashige Koba, Shigeo Shinohara
  • Publication number: 20050220827
    Abstract: The present invention provides a composition that can effectively improve melasma and a composition that can effectively reduce skin dullness. The composition for improving melasma comprises a purine nucleic acid-related substance and a pharmaceutically or cosmetically acceptable carrier, and exhibits an excellent melasma improving effect due to the action of the purine nucleic acid-related substance contained. The composition for reducing skin dullness comprises a purine nucleic acid-related substance and a pharmaceutically or cosmetically acceptable carrier, and exhibits an excellent effect of reducing skin dullness due to the action of the purine nucleic acid-related substance contained.
    Type: Application
    Filed: May 19, 2003
    Publication date: October 6, 2005
    Inventors: Hideo Tanaka, Masahiko Tanaka, Yasuo Furuta, Kosaburo Wakamatsu, Junko Kamimura, Fumiki Harano, Mitsuaki Kawamura, Shigekatsu Kawabata, Shigeo Shinohara, Noboru Yoshino
  • Publication number: 20040116373
    Abstract: An object of the invention is to provide a substance that activates saccharide uptake in epidermal cells and is thus expected to be effective in promoting skin cell neogenesis and metabolism. The invention provides a promoter for saccharide uptake in epidermal keratinocytes which comprises a purine base or a salt thereof as an active ingredient. The present invention further provides a method of promoting saccharide uptake in epidermal keratinocytes, comprising applying a purine base or a salt thereof to the skin.
    Type: Application
    Filed: October 14, 2003
    Publication date: June 17, 2004
    Inventors: Hiromichi Okuda, Chie Morimoto, Kenji Kameda, Fumiki Harano