Patents by Inventor Gabriele Fontana

Gabriele Fontana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9556099
    Abstract: Disclosed is a compound having the formula a) or b); a: R=CH3; b: R=CH2CH3, and its use in the prevention and/or treatment of Alzheimer's disease.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: January 31, 2017
    Assignee: INDENA S.P.A.
    Inventors: Paolo Morazzoni, Antonella Riva, Gabriele Fontana
  • Patent number: 9393280
    Abstract: The invention provides formulations containing sanguinarine, chelerythrine or chelidonine or their salts or extracts containing them, mixed with suitable vehicles and/or excipients, for the treatment of common skin warts and verrucas, anal and vulvar warts and psoriatic plaques.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: July 19, 2016
    Assignee: INDENA S.P.A.
    Inventors: Ezio Bombardelli, Gabriele Fontana, Paolo Morazzoni, Antonella Riva, Massimo Ronchi
  • Publication number: 20160115111
    Abstract: Disclosed is a compound having the formula a) or b); a: R=CH3; b: R=CH2CH3, and its use in the prevention and/or treatment of Alzheimer's disease.
    Type: Application
    Filed: June 17, 2014
    Publication date: April 28, 2016
    Inventors: Paolo Morazzoni, Antonella Riva, Gabriele Fontana
  • Patent number: 8940338
    Abstract: Formulations containing sanguinarine or chelerythrine or the salts thereof or extracts containing them in admixture with suitable carriers and/or excipients for the treatment and/or prevention of mucositis.
    Type: Grant
    Filed: January 8, 2009
    Date of Patent: January 27, 2015
    Assignee: Indena S.p.A.
    Inventors: Ezio Bombardelli, Gabriele Fontana
  • Patent number: 8772251
    Abstract: The invention concerns the use of glucomoringin and of its des-thio-glucoside having the following formulae (I, II): for the preparation of a medicament for the treatment of myeloma.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: July 8, 2014
    Assignee: Indena S.p.A.
    Inventors: Paolo Morazzoni, Carla Manzotti, Gabriele Fontana, Antonella Riva, Renato Iori
  • Patent number: 8624051
    Abstract: This invention relates to a “one pot” process for the preparation of isoserine derivatives in high diastereoselective way. The process according to the invention includes the steps of reacting a protected glycidic acid with imines to yield isoserines protected both at the —OH and at the —COOH groups, deprotection of the obtained intermediates to isoserines or isoserine 1-4C— alkyl esters. Pure threo derivatives as the main isomer are obtained.
    Type: Grant
    Filed: April 13, 2011
    Date of Patent: January 7, 2014
    Assignee: Indena S.p.A.
    Inventors: Gabriele Fontana, Maria Luisa Gelmi, Federico Gassa
  • Patent number: 8496975
    Abstract: The present invention relates to compositions comprising benzophenanthridine alkaloids, benzofuran compounds and catechin polyphenols, which are useful in the treatment and prevention of infections of the oral cavity.
    Type: Grant
    Filed: April 6, 2009
    Date of Patent: July 30, 2013
    Assignee: Indena S.p.A.
    Inventors: Ezio Bombardelli, Gabriele Fontana, Andrea Giori, Paolo Morazzoni, Antonella Riva, Massimo Ronchi
  • Publication number: 20130090493
    Abstract: This invention relates to a “one pot” process for the preparation of isoserine derivatives in high diastereoselective way. The process according to the invention includes the steps of reacting a protected glycidic acid with imines to yield isoserines protected both at the —OH and at the —COOH groups, deprotection of the obtained intermediates to isoserines or isoserine 1-4C— alkyl esters. Pure threo derivatives as the main isomer are obtained.
    Type: Application
    Filed: April 13, 2011
    Publication date: April 11, 2013
    Applicant: INDENA S.P.A
    Inventors: Gabriele Fontana, Maria Luisa Gelmi, Federico Gassa
  • Patent number: 8337903
    Abstract: The use of benzophenanthridine alkaloids and the salts thereof for the preparation of medicaments for the treatment of tumors is disclosed.
    Type: Grant
    Filed: February 16, 2009
    Date of Patent: December 25, 2012
    Assignee: Indena S.p.A.
    Inventors: Ezio Bombardelli, Gabriele Fontana, Paolo Morazzoni, Antonella Riva
  • Patent number: 8318957
    Abstract: A process for the preparation of 10-deacetyl-bis-7,10-trichloroacetylbaccatin III (VI) said process comprising: reacting 10-deacetylbaccatin III with a trichloroacetic acid activated derivative to obtain a reaction mixture, and performing an isolation step on said reaction mixture obtain purified 10-deacetyl-bis-7,10-trichloroacetylbaccatin III (VI) having a content, of corresponding 7- or 10 mono-trichloroacetyl derivatives lower than 0.1% as determined by HPLC.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: November 27, 2012
    Assignee: Indena S.p.A.
    Inventors: Bruno Gabetta, Andrea Gambini, Ezio Bombardelli, Gabriele Fontana
  • Publication number: 20120263810
    Abstract: The invention provides formulations containing sanguinarine, chelerythrine or chelidonine or their salts or extracts containing them, mixed with suitable vehicles and/or excipients, for the treatment of common skin warts and verrucas, anal and vulvar warts and psoriatic plaques.
    Type: Application
    Filed: June 22, 2012
    Publication date: October 18, 2012
    Applicant: INDENA S.P.A
    Inventors: Ezio Bombardelli, Gabriele Fontana, Paolo Morazzoni, Antonella Riva, Massimo Ronchi
  • Patent number: 8247005
    Abstract: The invention relates to a process for cosmetic treatment, including the reduction of superficial and deep wrinkles, using ferutinine from Ferula spp extracts.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: August 21, 2012
    Assignee: Indena S.p.A.
    Inventors: Ezio Bombarrdelli, Gabriele Fontana, Aldo Cristoni, Enrico Mercalli
  • Patent number: 8226994
    Abstract: The invention provides formulations containing sanguinarine, chelerythrine or chelidonine or their salts or extracts containing them, mixed with suitable vehicles and/or excipients, for the treatment of common skin warts and verrucas, anal and vulvar warts and psoriatic plaques.
    Type: Grant
    Filed: March 9, 2009
    Date of Patent: July 24, 2012
    Assignee: Indena S.p.A.
    Inventors: Ezio Bombardelli, Gabriele Fontana, Paolo Morazzoni, Antonella Riva, Massimo Ronchi
  • Patent number: 8217053
    Abstract: Novel camptothecin derivatives having antitumor activity, the processes for the preparation thereof, the use thereof as antitumor drugs and pharmaceutical compositions containing them.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: July 10, 2012
    Assignee: Indena S.p.A.
    Inventors: Gabriele Fontana, Ezio Bombardelli, Carla Manzotti, Arturo Battaglia, Maria Grazia Allegri, legal representative, Cristian Samori′
  • Patent number: 8193210
    Abstract: Novel camptothecin derivatives having antitumor activity, the processes for the preparation thereof, the use thereof as antitumor drugs and pharmaceutical compositions containing them.
    Type: Grant
    Filed: July 16, 2007
    Date of Patent: June 5, 2012
    Assignee: Indena S.p.A.
    Inventors: Gabriele Fontana, Ezio Bombardelli, Carla Manzotti, Arturo Battaglia, Maria Grazia Allegri, legal representative, Cristian Samori
  • Publication number: 20120095094
    Abstract: The invention relates to a process for cosmetic treatment, including the reduction of superficial and deep wrinkles, using ferutinine from Ferula spp extracts.
    Type: Application
    Filed: December 13, 2011
    Publication date: April 19, 2012
    Applicant: INDENA S.P.A.
    Inventors: Ezio BOMBARDELLI, Gabriele Fontana, Aldo Cristoni, Enrico Mercalli
  • Patent number: 8101215
    Abstract: The invention relates to a process for cosmetic treatment, including the reduction of superficial and deep wrinkles, using ferutinine from Ferula spp extracts.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: January 24, 2012
    Assignee: Indena S.p.A.
    Inventors: Ezio Bombarrdelli, Gabriele Fontana, Aldo Cristoni, Enrico Mercalli
  • Patent number: 8076351
    Abstract: Novel camptothecin derivatives having antitumor activity, the processes for the preparation thereof, the use thereof as antitumor drugs and pharmaceutical compositions containing them.
    Type: Grant
    Filed: July 12, 2007
    Date of Patent: December 13, 2011
    Assignee: Indena S.p.A.
    Inventors: Gabriele Fontana, Ezio Bombardelli, Carla Manzotti, Arturo Battaglia, Maria Grazia Allegri, legal representative, Cristian Samori
  • Publication number: 20110104313
    Abstract: The present invention relates to compositions comprising benzofuran compounds and benzophenanthridine alkaloids, which possess anti-inflammatory, antibacterial and antifungal activity useful in the treatment of vaginal infections and the resulting inflammatory states.
    Type: Application
    Filed: April 6, 2009
    Publication date: May 5, 2011
    Applicant: INDENA S.P.A
    Inventors: Ezio Bombardelli, Gabriele Fontana, Andrea Giori, Paolo Morazzoni, Antonella Riva, Massimo Ronchi
  • Publication number: 20110091392
    Abstract: The present invention relates to compositions comprising benzophenanthridine alkaloids, benzofuran compounds and catechin polyphenols, which are useful in the treatment and prevention of infections of the oral cavity.
    Type: Application
    Filed: April 6, 2009
    Publication date: April 21, 2011
    Applicant: INDENA S.P.A
    Inventors: Ezio Bombardelli, Gabriele Fontana, Andrea Giori, Paolo Morazzoni, Antonella Riva, Massimo Ronchi