Patents by Inventor Gaetano Barile

Gaetano Barile has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rage-related methods for treating and preventing diabetic retinopathy
    Publication number: 20080207499
    Abstract: This invention provides a method for treating diabetic retinopathy in a subject afflicted therewith, comprising administering to the subject's eyes a therapeutically effective amount of soluble RAGE or a derivative thereof, thereby treating diabetic retinopathy in the subject. This invention further provides a method for inhibiting the onset of diabetic retinopathy in a subject afflicted therewith, comprising administering a prophylactically effective amount of soluble RAGE or a derivative thereof to the subject's eyes, thereby inhibiting the onset of diabetic retinopathy in the subject.
    Type: Application
    Filed: June 28, 2006
    Publication date: August 28, 2008
    Inventors: Gaetano Barile, Ann Marie Schmidt
  • Methods for treating and preventing diabetic retinopathy
    Publication number: 20070098709
    Abstract: This invention provides a method for treating diabetic retinopathy in a subject afflicted therewith, comprising administering to the subject's eyes a therapeutically effective amount of an agent that modulates the binding between AGE and RAGE in the subject's eyes, wherein the agent is not soluble RAGE or a derivative thereof, thereby treating diabetic retinopathy in the subject. This invention further provides a method for inhibiting the onset of diabetic retinopathy in a subject comprising administering to the subject's eyes a prophylactically effective amount of an agent that modulates the binding between AGE and RAGE in the subject's eyes, wherein the agent is not soluble RAGE or a derivative thereof, thereby inhibiting the onset of diabetic retinopathy.
    Type: Application
    Filed: June 28, 2006
    Publication date: May 3, 2007
    Inventors: Gaetano Barile, Ann Schmidt