Abstract: A method includes applying one or more electrodes to the skin or skin surface of a subject, applying a voltage or current signal to the skin surface via one or more of the electrodes, and modulating the signal to maintain treatment efficacy, or so that the power output can be charge balanced, or both. An agent can be applied to the skin surface during a treatment period defined after the voltage or current signal is applied. Permeability of the skin to one or more components of the agent is enhanced or increased during the treatment period, responsive to the modulated power output. A device for performing the method is also provided.

Abstract: Topical compositions, packaging systems and methods for improving the appearance of skin or at least one sign of aging in skin are described.

Abstract: Compositions for topical use and having a melanin synthesis-inhibiting activity that include an amount of a botanical extract of at least one of Aspalathus Linearis, Matricaria, Saxifraga, Astragalus, Taraxacum officinale/mongolicum, Ferula varia/foetida, Carthamus tinctorius, Sophora flavescentis, or Chrysanthemum morifolium effective to reduce melanin synthesis are described. Methods for inhibiting melanin synthesis and for skin whitening are also described.

Abstract: Topical compositions, packaging systems and methods for improving the appearance of skin or at least one sign of aging in skin are described.

Abstract: Compositions for topical use and having a melanin synthesis-inhibiting activity that include an amount of a botanical extract of at least one of Aspalathus Linearis, Matricaria, Saxifraga, Astragalus, Taraxacum officinale/mongolicum, Ferula varia/foetida, Carthamus tinctorius, Sophora flavescentis, or Chrysanthemum morifolium effective to reduce melanin synthesis are described. Methods for inhibiting melanin synthesis and for skin whitening are also described.

Abstract: A topical composition includes an alcohol-extracted Salvia hispanica seed extract in a glycol carrier in an amount effective for inhibiting melanin content in an individual. The extract may be extracted in a C1-C4 ethanol and re-suspended in a glycol carrier with one or more permeation enhancers. The topical composition may further include a Punica granatum extract. Methods for making and using the composition for whitening skin in an individual are also described.

Abstract: A topical composition includes an alcohol-extracted Salvia hispanica seed extract in a glycol carrier in an amount effective for inhibiting melanin content in an individual. The extract may be extracted in a C1-C4 ethanol and re-suspended in a glycol carrier with one or more permeation enhancers. The topical composition may further include a Punica granatum extract. Methods for making and using the composition for whitening skin in an individual are also described.

Abstract: A topical composition includes an alcohol-extracted Salvia hispanica seed extract in a glycol carrier in an amount effective for inhibiting melanin content in an individual. The extract may be extracted in a C1-C4 ethanol and resuspended in a glycol carrier with one or more permeation enhancers. The topical composition may further include a Punica granatum extract. Methods for making and using the composition for whitening skin in an individual are also described.

Abstract: A topical cosmetic composition for skin whitening or skin lightening is described. The composition includes an aqueous extract of Caesalpinia spinosa, also known as Tara, in an amount effective to reduce melanin production. The composition may also include an extract of Centella asiatica, also known as Gotu Kola. A method for using the compositions is also described.

Abstract: A topical cosmetic composition for increasing skin whitening or lightening is described. The composition includes a pomegranate extract in an amount effective to reduce melanin composition. The pomegranate extract may be standardized to about 20% punicalagin. The composition may also include an extract from the genus larix, such as Larix sibirica. The larix sibirica may be standardized to 80% taxifolin. A method for using the compositions is described.

Abstract: A topical composition includes an alcohol-extracted Salvia hispanica seed extract in a glycol carrier in an amount effective for inhibiting melanin content in an individual. The extract may be extracted in a C1-C4 ethanol and resuspended in a glycol carrier with one or more permeation enhancers. The topical composition may further include a Punica granatum extract. Methods for making and using the composition for whitening skin in an individual are also described.

Abstract: A topical cosmetic composition for increasing skin whitening or lightening is described. The composition includes a pomegranate extract in an amount effective to reduce melanin composition. The pomegranate extract may be standardized to about 20% punicalagin. The composition may also include an extract from the genus larix, such as Larix sibirica. The larix sibirica may be standardized to 80% taxifolin. A method for using the compositions is described.

Abstract: A topical cosmetic composition for increasing skin whitening or lightening is described. The composition includes a pomegranate extract in an amount effective to reduce melanin composition. The pomegranate extract may be standardized to about 20% punicalagin. The composition may also include an extract from the genus larix, such as Larix sibirica. The larix sibirica may be standardized to 80% taxifolin. A method for using the compositions is described.

Abstract: A topical cosmetic composition for increasing skin whitening or lightening is described. The composition includes a pomegranate extract in an amount effective to reduce melanin composition. The pomegranate extract may be standardized to about 20% punicalagin. The composition may also include an extract from the genus larix, such as Larix sibirica. The larix sibirica may be standardized to 80% taxifolin. A method for using the compositions is described.