Abstract: The present disclosure relates to antibodies and antibody conjugates having one or more site-specific mutations in the CH2 domain of the heavy chain. The antibody variants disclosed herein can have improved characteristics (e.g., thermal stability, antibody yields, antibody titers, cell-killing) relative to a parent or wild type antibody, including aglycosylated parent or wild type antibodies. Pharmaceutical compositions, diagnostic compositions and kits comprising the same, as well as methods of using these compositions and kits for therapeutic and diagnostic purposes, are also described.

Abstract: The present application discloses a dredging system for a pre-paved gravel foundation bed surface in open sea deep water, including a dredging mechanism, which includes a dredging suction head, a power component and a dredging pipeline, wherein the dredging suction head is connected with the dredging pipeline; the dredging pipeline is communicated with the power component; the dredging suction head includes at least one ridge surface suction port and at least one furrow suction port; the openings of all the furrow suction ports are lower than those of all the ridge surface suction ports; a lifting mechanism, which is connected with the dredging suction head and is used for lifting the dredging suction head to the gravel foundation bed surface; a moving mechanism, which is connected with the lifting mechanism and is used for driving the dredging suction head to move within a dredging range of the gravel foundation bed surface.

Abstract: The present disclosure relates to antibody conjugates with binding specificity for folate receptor alpha (FOLR1) and its isoforms and homologs, and compositions comprising the antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibody conjugates and compositions as well as methods of using the antibody conjugates and compositions, such as in therapeutic and diagnostic methods.

Abstract: In an approach to threshold setting for pie charts, a computing device displays one or more pie charts. The computing device receives an instruction to enter Threshold-Setting Mode. The computing device displays one or more threshold-setting flags associated with one or more pie chart slices and one or more indicators associated with the one or more pie chart slices. The computing device receives an instruction to set a threshold associated with a slice. The computing device updates a percentage displayed on an indicator associated with the threshold. The computing device displays the threshold as a virtual slice.

Abstract: The invention provides methods for producing a protein in a cell free protein synthesis system such that the protein does not contain an asparagine (Asn or N) residue at serine (Ser or S) positions. Also provided are compositions and nucleic acid templates for use in the methods described herein.

Abstract: Provided herein are antibodies comprising multiple non-natural amino acid residues at site-specific positions, compositions comprising the antibodies, methods of their production and methods of their use. The antibodies are useful for methods of treatment and prevention, methods of detection and methods of diagnosis.

Abstract: Provided herein are antibodies comprising non-natural amino acid residues at site-specific positions, compositions comprising the antibodies, methods of their production and methods of their use. The antibodies are useful for methods of treatment and prevention, methods of detection and methods of diagnosis.

Abstract: Provided herein are modified Fc proteins comprising non-natural amino acid residues at site-specific positions, conjugates of the modified Fc proteins for therapy or diagnosis, compositions comprising the modified Fc proteins and conjugates thereof, methods of their production and methods of their use. The modified Fc proteins and conjugates are useful for methods of treatment and prevention, methods of detection and methods of diagnosis.

Abstract: Provided herein are antibodies comprising multiple non-natural amino acid residues at site-specific positions, compositions comprising the antibodies, methods of their production and methods of their use. The antibodies are useful for methods of treatment and prevention, methods of detection and methods of diagnosis.

Abstract: Provided herein are antibodies comprising non-natural amino acid residues at site-specific positions, compositions comprising the antibodies, methods of their production and methods of their use. The antibodies are useful for methods of treatment and prevention, methods of detection and methods of diagnosis.

Abstract: Provided herein are modified Fc proteins comprising non-natural amino acid residues at site-specific positions, conjugates of the modified Fc proteins for therapy or diagnosis, compositions comprising the modified Fc proteins and conjugates thereof, methods of their production and methods of their use. The modified Fc proteins and conjugates are useful for methods of treatment and prevention, methods of detection and methods of diagnosis.

Abstract: In an approach to threshold setting for pie charts, a computing device displays one or more pie charts. The computing device receives an instruction to enter Threshold-Setting Mode. The computing device displays one or more threshold-setting flags associated with one or more pie chart slices and one or more indicators associated with the one or more pie chart slices. The computing device receives an instruction to set a threshold associated with a slice. The computing device updates a percentage displayed on an indicator associated with the threshold. The computing device displays the threshold as a virtual slice.

Abstract: A motherboard assembly able to use a PCI slot either to expand system function or for the installation of additional memory includes a motherboard and a storage device. The motherboard includes a PCI expansion slot, a platform controller hub (PCH), and a power circuit. The PCI expansion slot includes a protrusion, four idle pins and first signal pins connected to the PCH, and first power pins connected to the power circuit. A control chip, a number of storage chips connected to the control chip, and a power unit are arranged on the storage device. A non-central notch is included in an edge connector arranged on a bottom edge of the storage device and the edge connector allows for power pins connected to the power unit and signal pins connected to the control chip.

Abstract: An exemplary electronic device includes a mother board, a power source, and a power extending board detachably connected between the power source and the motherboard. The power source includes a golden finger interface. The power extending board includes a receiving socket, a first conversion circuit, and a first connector. The golden finger interface is plugged into the receiving socket. The first conversion circuit is connected to the receiving socket, converts first and second voltages from the power source into third and fourth voltages, and outputs the first, third, and fourth voltages to the motherboard.

Abstract: A storage expansion system includes an expansion apparatus and a serial advanced technology attachment dual in-line memory module (SATA DIMM) device. A memory slot, a SATA port, a SATA signal expansion member, and a voltage converter are arranged on the expansion apparatus. The memory slot includes first power pins, first ground pins, and first signal pins connected to the SATA signal expansion member. A first edge connector is arranged on a side of the expansion apparatus. The first edge connector includes second power pins and second ground pins. The first and second power pins are connected to the voltage converter. A second edge connector is arranged on a bottom side of the SATA DIMM device. The second edge connector includes third power pins connected to a control chip and storage chips, third ground pins, and second signal pins connected to the control chip.

Abstract: In an approach to threshold setting for pie charts, a computing device displays one or more pie charts. The computing device receives an instruction to enter Threshold-Setting Mode. The computing device displays one or more threshold-setting flags associated with one or more pie chart slices and one or more indicators associated with the one or more pie chart slices. The computing device receives an instruction to set a threshold associated with a slice. The computing device updates a percentage displayed on an indicator associated with the threshold. The computing device displays the threshold as a virtual slice.

Abstract: In an approach to threshold setting for pie charts, a computing device displays one or more pie charts. The computing device receives an instruction to enter Threshold-Setting Mode. The computing device displays one or more threshold-setting flags associated with one or more pie chart slices and one or more indicators associated with the one or more pie chart slices. The computing device receives an instruction to set a threshold associated with a slice. The computing device updates a percentage displayed on an indicator associated with the threshold. The computing device displays the threshold as a virtual slice.

Abstract: A positioning apparatus for installing a server unit on a rack includes a frame fixed to the server unit, an operation member slidably installed to the frame, a pivot member sandwiched between the frame and the operation member, and a resilient member connected between the frame and the operation member. A rear end of the pivot member is rotatably connected to the frame, and a latching piece protrudes out from a front end of the pivot member. The pivot member defines a guiding slot. The frame defines a through slot aligning with the latching piece. The operation member includes a sliding pole protruding from the operation member and extending through the guiding slot. The resilient member biases the operation member to move, the sliding pole slides in the guiding slot to rotate the pivot member, and the latching piece extends through the through slot to latch onto the rack.

Abstract: A mounting apparatus for an expansion card includes a bracket, a circuit board mounted in the bracket, and a latching member. The bracket includes a bottom wall, a supporting wall perpendicularly mounted on the bottom wall, and a first end wall and a second end wall extending from two opposite ends of the supporting wall along the same direction. The circuit board includes a connector. The latching member includes a first hook and a mounting piece. The latching member is slidably installed to the first end wall. The mounting piece is exposed out of the bottom wall of the bracket. The expansion card is inserted into the connector of the circuit board, a front end of the expansion card is mounted to the second end wall, and a rear end of the expansion card is latched to the first hook of the latching member.

Abstract: An electronic device enclosure includes a casing, an air duct mounted in the casing, and a latching member. The air duct includes a receiving bracket formed on the air duct for receiving an uninterruptible power supply module. The latching member is covered on the receiving bracket to position the uninterruptible power supply module. A first side of the latching member is rotatably connected to the receiving bracket, and a second side of the latching member is detachably latched to the receiving bracket.