Patents by Inventor Gaoyuan Gavin Chen

Gaoyuan Gavin Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210322624
    Abstract: Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.
    Type: Application
    Filed: June 16, 2021
    Publication date: October 21, 2021
    Applicant: Ethicon, Inc.
    Inventors: Dennis D. Jamiolkowski, Christopher DeFelice, Sasa Andjelic, Brian M. Kelly, Marc Wisnudel, Daniel Steiger, Gaoyuan Gavin Chen
  • Patent number: 11136696
    Abstract: A novel process is disclosed for extruding an absorbable glycolide/lactide block copolymer into multifilament suture fibers. The block copolymer preferably consists of about 50/50 mole % of Glycolide/Lactide in the center segment and the overall composition of the copolymer is about 90/10 mole % Glycolide/Lactide. The novel extrusion process comprises the steps of maintaining the temperatures of at least two, preferably three or more, of the extrusion zones in the range of about 5-50° C. below the polymer melting point. The multifilament suture made with the invention process from the segmented, glycolide-rich, poly(glycolide-co-lactide) copolymers of A-B-A type, where the B-segment is an amorphous prepolymer of glycolide and lactide in the molar ratio of about 50/50 glycolide/lactide, exhibit exceptionally high breaking strength retention (BSR) at 42 days post-implantation.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: October 5, 2021
    Assignee: Ethicon, Inc.
    Inventors: Gaoyuan Gavin Chen, Joseph Richard Vliet, Jr., Dominick Egidio
  • Patent number: 11058792
    Abstract: Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: July 13, 2021
    Assignee: Ethicon, Inc.
    Inventors: Dennis D. Jamiolkowski, Christopher DeFelice, Sasa Andjelic, Brian M. Kelly, Marc Wisnudel, Daniel Steiger, Gaoyuan Gavin Chen
  • Publication number: 20200149194
    Abstract: A novel process is disclosed for extruding an absorbable glycolide/lactide block copolymer into multifilament suture fibers. The block copolymer preferably consists of about 50/50 mole % of Glycolide/Lactide in the center segment and the overall composition of the copolymer is about 90/10 mole % Glycolide/Lactide. The novel extrusion process comprises the steps of maintaining the temperatures of at least two, preferably three or more, of the extrusion zones in the range of about 5-50° C. below the polymer melting point. The multifilament suture made with the invention process from the segmented, glycolide-rich, poly(glycolide-co-lactide) copolymers of A-B-A type, where the B-segment is an amorphous prepolymer of glycolide and lactide in the molar ratio of about 50/50 glycolide/lactide, exhibit exceptionally high breaking strength retention (BSR) at 42 days post-implantation.
    Type: Application
    Filed: November 8, 2018
    Publication date: May 14, 2020
    Inventors: Gaoyuan Gavin Chen, Joseph Richard Vliet, JR., Dominick Egidio
  • Publication number: 20200000958
    Abstract: Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.
    Type: Application
    Filed: June 28, 2018
    Publication date: January 2, 2020
    Inventors: Dennis D. Jamiolkowski, Christopher DeFelice, Sasa Andjelic, Brian M. Kelly, Marc Wisnudel, Daniel Steiger, Gaoyuan Gavin Chen
  • Patent number: 9949823
    Abstract: Novel bioabsorbable, universal kits used to form nasal implants are disclosed. The implants are useful in rhinoplasty and nasal reconstruction surgical procedures. The kit devices have a universal configuration and can be converted by the surgeon in the field into one or more individual nasal implant devices having different configurations and applications. The kits may have outlines of nasal implants thereon.
    Type: Grant
    Filed: May 5, 2015
    Date of Patent: April 24, 2018
    Assignee: Ethicon, Inc
    Inventors: Krasimira Hristov, Gaoyuan Gavin Chen, Mark T. Mooney, James A. Matrunich, Jianxin Guo, Emil Richard Skula
  • Patent number: 9636207
    Abstract: An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries.
    Type: Grant
    Filed: March 30, 2011
    Date of Patent: May 2, 2017
    Assignee: Ethicon, Inc.
    Inventors: Robert A. Rousseau, David C. Lindh, Sr., John R. Jacobs, Ilya S. Koyfman, Gaoyuan Gavin Chen, Donald G. Hill
  • Publication number: 20150230917
    Abstract: Novel bioabsorbable, universal kits used to form nasal implants are disclosed. The implants are useful in rhinoplasty and nasal reconstruction surgical procedures. The kit devices have a universal configuration and can be converted by the surgeon in the field into one or more individual nasal implant devices having different configurations and applications. The kits may have outlines of nasal implants thereon.
    Type: Application
    Filed: May 5, 2015
    Publication date: August 20, 2015
    Inventors: Krasimira Hristov, Gaoyuan Gavin Chen, Mark T. Mooney, James A. Matrunich, Jianxin Guo, Emil Richard Skula
  • Publication number: 20130317540
    Abstract: Novel bioabsorbable, universal kits used to form nasal implants are disclosed. The implants are useful in rhinoplasty and nasal reconstruction surgical procedures. The kit devices have a universal configuration and can be converted by the surgeon in the field into one or more individual nasal implant devices having different configurations and applications. The kits may have outlines of nasal implants thereon.
    Type: Application
    Filed: May 22, 2012
    Publication date: November 28, 2013
    Inventors: Krasimira Hristov, Gaoyuan Gavin Chen, Mark T. Mooney, James A. Matrunich, Jianxin Guo, Emil Richard Skula
  • Patent number: 8591534
    Abstract: An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: November 26, 2013
    Assignee: Ethicon, Inc.
    Inventors: Robert A. Rousseau, David C. Lindh, Sr., John R. Jacobs, Ilya S. Koyfman, Gaoyuan Gavin Chen, Donald G. Hill
  • Patent number: 8388633
    Abstract: An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries.
    Type: Grant
    Filed: March 30, 2011
    Date of Patent: March 5, 2013
    Assignee: Ethicon, Inc.
    Inventors: Robert A. Rousseau, David C. Lindh, Sr., John R. Jacobs, Ilya S. Koyfman, Gaoyuan Gavin Chen, Donald G. Hill
  • Publication number: 20110178608
    Abstract: An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries.
    Type: Application
    Filed: March 30, 2011
    Publication date: July 21, 2011
    Inventors: Robert A. Rousseau, David C. Lindh, SR., John R. Jacobs, Ilya S. Koyfman, Gaoyuan Gavin Chen, Donald G. Hill
  • Publication number: 20110172786
    Abstract: An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries.
    Type: Application
    Filed: March 30, 2011
    Publication date: July 14, 2011
    Inventors: Robert A. Rousseau, David C. Lindh, SR., John R. Jacobs, Ilya S. Koyfman, Gaoyuan Gavin Chen, Donald G. Hill
  • Patent number: 7875074
    Abstract: A preformed, seamless, three-dimensional, anatomically contoured prosthetic device for reinforcing breast tissue and supporting a breast implant includes a flat back wall, a concave front wall and a curved transitional region between the flat back wall and the front wall defining a smoothly curved bottom periphery. A concave receiving space is defined by the back wall and the front wall for at least partially receiving and supporting the breast implant therein. The three-dimensional prosthetic device is free of wrinkles, creases, folds or seams, which may have otherwise caused potential tissue irritation, bacteria hosting, infection and palpability problems.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: January 25, 2011
    Assignee: Ethicon, Inc.
    Inventors: Gaoyuan Gavin Chen, James Matrunich, Robert J. Tannhauser
  • Publication number: 20100312358
    Abstract: An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries.
    Type: Application
    Filed: August 18, 2010
    Publication date: December 9, 2010
    Inventors: Robert A. Rousseau, David C. Lindh, SR., John R. Jacobs, Ilya S. Koyfman, Gaoyuan Gavin Chen, Donald G. Hill
  • Patent number: 7828854
    Abstract: An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material is disclosed. The first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries.
    Type: Grant
    Filed: October 31, 2006
    Date of Patent: November 9, 2010
    Assignee: Ethicon, Inc.
    Inventors: Robert A. Rousseau, David C. Lindh, Sr., John R. Jacobs, Ilya S. Koyfman, Gaoyuan Gavin Chen, Donald G. Hill
  • Publication number: 20090082864
    Abstract: A preformed, seamless, three-dimensional, anatomically contoured prosthetic device for reinforcing breast tissue and supporting a breast implant includes a flat back wall, a concave front wall and a curved transitional region between the flat back wall and the front wall defining a smoothly curved bottom periphery. A concave receiving space is defined by the back wall and the front wall for at least partially receiving and supporting the breast implant therein. The three-dimensional prosthetic device is free of wrinkles, creases, folds or seams, which may have otherwise caused potential tissue irritation, bacteria hosting, infection and palpability problems.
    Type: Application
    Filed: September 19, 2008
    Publication date: March 26, 2009
    Inventors: Gaoyuan Gavin Chen, James Matrunich, Robert J. Tannhauser
  • Publication number: 20080147200
    Abstract: An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries.
    Type: Application
    Filed: October 31, 2006
    Publication date: June 19, 2008
    Inventors: Robert A. Rousseau, David C. Lindh, John R. Jacobs, Ilya S. Koyfman, Gaoyuan Gavin Chen, Donald G. Hill