Patents by Inventor Garry M. Steil

Garry M. Steil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190053742
    Abstract: A system and method for controlling and monitoring a diabetes-management system through the use of a model that predicts or estimates future dynamic states of glucose and insulin from variables such as insulin delivery or exogenous glucose appearance as well as inherent physiological parameters. The model predictive estimator can be used as an insulin bolus advisor to give an apriori estimate of postprandial glucose for a given insulin delivery profile administered with a known meal to optimize insulin delivery; as a supervisor to monitor the operation of the diabetes-management system; and as a model predictive controller to optimize the automated delivery of insulin into a user's body to achieve a desired blood glucose profile or concentration. Open loop, closed-loop, and semi-closed loop embodiments of the invention utilize a mathematical metabolic model that includes a Minimal Model, a Pump Delivery to Plasma Insulin Model, and a Meal Appearance Rate Model.
    Type: Application
    Filed: October 9, 2018
    Publication date: February 21, 2019
    Inventors: GARRY M. STEIL, SAMI S. KANDERIAN, JR., MARTIN T. CANTWELL, UDO HOSS
  • Patent number: 10154804
    Abstract: A system and method for controlling and monitoring a diabetes-management system through the use of a model that predicts or estimates future dynamic states of glucose and insulin from variables such as insulin delivery or exogenous glucose appearance as well as inherent physiological parameters. The model predictive estimator can be used as an insulin bolus advisor to give an apriori estimate of postprandial glucose for a given insulin delivery profile administered with a known meal to optimize insulin delivery; as a supervisor to monitor the operation of the diabetes-management system; and as a model predictive controller to optimize the automated delivery of insulin into a user's body to achieve a desired blood glucose profile or concentration. Open loop, closed-loop, and semi-closed loop embodiments of the invention utilize a mathematical metabolic model that includes a Minimal Model, a Pump Delivery to Plasma Insulin Model, and a Meal Appearance Rate Model.
    Type: Grant
    Filed: January 31, 2007
    Date of Patent: December 18, 2018
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Garry M. Steil, Sami S. Kanderian, Jr., Martin T. Cantwell
  • Patent number: 10080529
    Abstract: Apparatuses and methods for medical monitoring physiological characteristics values such as blood glucose levels for the treatment of diabetes, are presented. The apparatuses and methods provide dynamic glucose monitoring functions that perform predictive analysis to anticipate harmful conditions, such as glucose crash and hyperglycemic incidents for a patient. The dynamic functions can also be used to maximize athletic performance and warn of inadequate nocturnal basal rate. Other aspects include advanced alarm and reminder functions, as well as advanced data presentation tools to further facilitate convenient and efficient management of various physiological conditions.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: September 25, 2018
    Assignee: Medtronic MiniMed, Inc.
    Inventors: James Kelly Fox, Garry M. Steil, Kerstin Rebrin, Mark C. Estes, Frank Saidara
  • Patent number: 9968742
    Abstract: Embodiments of the invention provide a dual insertion set for supplying a fluid to a body of a patient and for monitoring a body characteristic of the patient. Typical embodiments of the invention include a base, an infusion portion coupled to a first piercing member and a sensor portion coupled to a second piercing member. The infusion portion includes a cannula coupled to the first piercing member for supplying the fluid to a placement site. The sensor portion includes a sensor coupled to and extending from the base having at least one sensor electrode formed on a substrate and is coupled to the second piercing member in a manner that allows the sensor to be inserted at the placement site. The base is arranged to secure the dual insertion set to skin of the patient.
    Type: Grant
    Filed: August 29, 2007
    Date of Patent: May 15, 2018
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Nannette M. Van Antwerp, Rajiv Shah, Bradley J. Enegren, Richard Lemos, Jr., Ly Phou, Garry M. Steil, Gayane R. Voskanyan
  • Publication number: 20170325736
    Abstract: Disclosed are a method and/or system for determining a suggested change in a recommended therapy for a patient based, at least in part, on sensor measurements, and generating an alert to an attendant in a hospital environment upon detection of the suggested change. In another embodiment, a method and/or system is directed to automatically determining a maximum interval to alert an attendant following receipt of a measurement at an operator interface. In yet another embodiment, a method and/or system is directed to blood-glucose sensor calibration.
    Type: Application
    Filed: June 1, 2017
    Publication date: November 16, 2017
    Inventors: Martin Cantwell, H. Bud Clark, Garry M. Steil
  • Patent number: 9795738
    Abstract: An algorithm and method of making intelligent therapy recommendations for insulin pump parameters is described. The pump parameters include basal rates, carbohydrate-to-insulin ratios (CIR), and insulin sensitivity factors (ISF). A determination of whether a therapy recommendation should be made is based on comparing an updated recommended change with a threshold. The updated recommended change to the pump parameter is made based on a previous recommended change to the pump parameter and the difference between a current blood glucose value and a targeted blood glucose level. The algorithm and method confirms the therapy recommendation is within safety parameters before displaying the therapy recommendation.
    Type: Grant
    Filed: May 10, 2015
    Date of Patent: October 24, 2017
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Garry M. Steil, Antonios Panteleon
  • Patent number: 9687194
    Abstract: Disclosed are a method and/or system for determining a suggested change in a recommended therapy for a patient based, at least in part, on sensor measurements, and generating an alert to an attendant in a hospital environment upon detection of the suggested change. In another embodiment, a method and/or system is directed to automatically determining a maximum interval to alert an attendant following receipt of a measurement at an operator interface. In yet another embodiment, a method and/or system is directed to blood-glucose sensor calibration.
    Type: Grant
    Filed: June 17, 2009
    Date of Patent: June 27, 2017
    Assignee: Medtronic Minimed, Inc.
    Inventors: Martin Cantwell, H. Bud Clark, Garry M. Steil
  • Patent number: 9440025
    Abstract: An infusion system, which may be a closed loop infusion system or “semi-closed-loop” system, uses state variable feedback to control the rate that fluid is infused into the body of a user. The closed loop infusion system includes a sensor system, a controller, and a delivery system. The “semi-closed-loop” system further includes prompts that are displayed or sounded or otherwise provide indications to the user prior to fluid delivery. The sensor system includes a sensor for monitoring a condition of the user. The sensor produces a sensor signal, which is representative of the condition of the user. The delivery system infuses a fluid into the user at a rate dictated by the commands from the controller. The system may use three state variables, subcutaneous insulin concentration, plasma insulin concentration, and insulin effect, and corresponding gains, to calculate an additional amount of fluid to be infused as a bolus and to be removed from the basal delivery of the fluid.
    Type: Grant
    Filed: May 13, 2014
    Date of Patent: September 13, 2016
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Sami S. Kanderian, Jr., Garry M. Steil
  • Patent number: 9320471
    Abstract: An infusion system is for infusing a fluid into the body of a patient. The infusion system includes at least one sensor for monitoring blood glucose concentration of the patient and an infusion device for delivering fluid to the patient. The sensor produces at least one sensor signal input. The infusion device uses the at least one sensor signal input and a derivative predicted algorithm to determine future blood glucose levels. The infusion device delivers fluid to the patient when future blood glucose levels are in a patient's target range. The infusion device is capable of suspending and resuming fluid delivery based on future blood glucose levels and a patient's low shutoff threshold. The infusion device suspends fluid delivery when future blood glucose levels falls below the low shutoff threshold. The infusion device resumes fluid delivery when a future blood glucose level is above the low shutoff threshold.
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: April 26, 2016
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Andrew C. Hayes, John J. Mastrototaro, Sheldon B. Moberg, John C. Mueller, Jr., H. Bud Clark, Mike Charles Vallet Tolle, Gary L. Williams, Bihong Wu, Garry M. Steil
  • Publication number: 20150238694
    Abstract: An algorithm and method of making intelligent therapy recommendations for insulin pump parameters is described. The pump parameters include basal rates, carbohydrate-to-insulin ratios (CIR), and insulin sensitivity factors (ISF). A determination of whether a therapy recommendation should be made is based on comparing an updated recommended change with a threshold. The updated recommended change to the pump parameter is made based on a previous recommended change to the pump parameter and the difference between a current blood glucose value and a targeted blood glucose level. The algorithm and method confirms the therapy recommendation is within safety parameters before displaying the therapy recommendation.
    Type: Application
    Filed: May 10, 2015
    Publication date: August 27, 2015
    Inventors: Garry M. Steil, Antonios Panteleon
  • Publication number: 20150190100
    Abstract: Apparatuses and methods for medical monitoring physiological characteristics values such as blood glucose levels for the treatment of diabetes, are presented. The apparatuses and methods provide dynamic glucose monitoring functions that perform predictive analysis to anticipate harmful conditions, such as glucose crash and hyperglycemic incidents for a patient. The dynamic functions can also be used to maximize athletic performance and warn of inadequate nocturnal basal rate. Other aspects include advanced alarm and reminder functions, as well as advanced data presentation tools to further facilitate convenient and efficient management of various physiological conditions.
    Type: Application
    Filed: January 16, 2015
    Publication date: July 9, 2015
    Inventors: James Kelly Fox, Garry M. Steil, Kerstin Rebrin, Mark C. Estes, Frank Saidara
  • Patent number: 9056165
    Abstract: An algorithm and method of making intelligent therapy recommendations for insulin pump parameters is described. The pump parameters include basal rates, carbohydrate-to-insulin ratios (CIR), and insulin sensitivity factors (ISF). A determination of whether a therapy recommendation should be made is based on comparing an updated recommended change with a threshold. The updated recommended change to the pump parameter is made based on a previous recommended change to the pump parameter and the difference between a current blood glucose value and a targeted blood glucose level. The algorithm and method confirms the therapy recommendation is within safety parameters before displaying the therapy recommendation.
    Type: Grant
    Filed: September 6, 2006
    Date of Patent: June 16, 2015
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Garry M. Steil, Antonios Panteleon
  • Publication number: 20140303552
    Abstract: An infusion system, which may be a closed loop infusion system or “semi-closed-loop” system, uses state variable feedback to control the rate that fluid is infused into the body of a user. The closed loop infusion system includes a sensor system, a controller, and a delivery system. The “semi-closed-loop” system further includes prompts that are displayed or sounded or otherwise provide indications to the user prior to fluid delivery. The sensor system includes a sensor for monitoring a condition of the user. The sensor produces a sensor signal, which is representative of the condition of the user. The delivery system infuses a fluid into the user at a rate dictated by the commands from the controller. The system may use three state variables, subcutaneous insulin concentration, plasma insulin concentration, and insulin effect, and corresponding gains, to calculate an additional amount of fluid to be infused as a bolus and to be removed from the basal delivery of the fluid.
    Type: Application
    Filed: May 13, 2014
    Publication date: October 9, 2014
    Applicant: MEDTRONIC MINIMED, INC.
    Inventors: SAMI S. KANDERIAN, JR., GARRY M. STEIL
  • Patent number: 8777924
    Abstract: An infusion system, which may be a closed loop, or “semi-closed-loop”, infusion system, uses state variable feedback to control the rate at which fluid is infused into a user's body. The closed loop system includes a sensor system, a controller, and a delivery system. The “semi-closed-loop” system further includes prompts that provide indications to the user prior to fluid delivery. The sensor system includes a sensor for monitoring a condition of the user and produces a sensor signal which is representative of the user's condition. The delivery system infuses a fluid into the user at a rate dictated by the commands from the controller. The system may use three state variables, e.g., subcutaneous insulin concentration, plasma insulin concentration, and insulin effect, and corresponding gains, to calculate an additional amount of fluid to be infused with a bolus and to be removed from the basal delivery of the fluid.
    Type: Grant
    Filed: December 3, 2012
    Date of Patent: July 15, 2014
    Assignee: Medtronic Minimed, Inc.
    Inventors: Sami S. Kanderian, Jr., Garry M. Steil
  • Patent number: 8771222
    Abstract: An infusion system, which may be a closed loop infusion system or “semi-closed-loop” system, uses state variable feedback to control the rate that fluid is infused into the body of a user. The closed loop infusion system includes a sensor system, a controller, and a delivery system. The “semi-closed-loop” system further includes prompts that are displayed or sounded or otherwise provide indications to the user prior to fluid delivery. The sensor system includes a sensor for monitoring a condition of the user. The sensor produces a sensor signal, which is representative of the condition of the user. The delivery system infuses a fluid into the user at a rate dictated by the commands from the controller. The system may use three state variables, subcutaneous insulin concentration, plasma insulin concentration, and insulin effect, and corresponding gains, to calculate an additional amount of fluid to be infused as a bolus and to be removed from the basal delivery of the fluid.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: July 8, 2014
    Assignee: Medtronic Minimed, Inc.
    Inventors: Sami S. Kanderian, Jr., Garry M. Steil
  • Patent number: 8348886
    Abstract: An infusion system, which may be a closed loop infusion system or “semi-closed-loop” system, uses state variable feedback to control the rate that fluid is infused into the body of a user. The closed loop infusion system includes a sensor system, a controller, and a delivery system. The “semi-closed-loop” system further includes prompts that are displayed or sounded or otherwise provide indications to the user prior to fluid delivery. The sensor system includes a sensor for monitoring a condition of the user. The sensor produces a sensor signal, which is representative of the condition of the user. The delivery system infuses a fluid into the user at a rate dictated by the commands from the controller. The system may use three state variables, subcutaneous insulin concentration, plasma insulin concentration, and insulin effect, and corresponding gains, to calculate an additional amount of fluid to be infused as a bolus and to be removed from the basal delivery of the fluid.
    Type: Grant
    Filed: May 1, 2009
    Date of Patent: January 8, 2013
    Assignee: Medtronic Minimed, Inc.
    Inventors: Sami S. Kanderian, Jr., Garry M. Steil
  • Patent number: 8348923
    Abstract: An infusion system, which may be a closed loop, or “semi-closed-loop”, infusion system, uses state variable feedback to control the rate at which fluid is infused into a user's body. The closed loop system includes a sensor system, a controller, and a delivery system. The “semi-closed-loop” system further includes prompts that provide indications to the user prior to fluid delivery. The sensor system includes a sensor for monitoring a condition of the user and produces a sensor signal which is representative of the user's condition. The delivery system infuses a fluid into the user at a rate dictated by the commands from the controller. The system may use three state variables, e.g., subcutaneous insulin concentration, plasma insulin concentration, and insulin effect, and corresponding gains, to calculate an additional amount of fluid to be infused with a bolus and to be removed from the basal delivery of the fluid.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: January 8, 2013
    Assignee: Medtronic Minimed, Inc.
    Inventors: Sami S. Kanderian, Jr., Garry M. Steil
  • Publication number: 20120259278
    Abstract: An infusion system is for infusing a fluid into the body of a patient. The infusion system includes at least one sensor for monitoring blood glucose concentration of the patient and an infusion device for delivering fluid to the patient. The sensor produces at least one sensor signal input. The infusion device uses the at least one sensor signal input and a derivative predicted algorithm to determine future blood glucose levels. The infusion device delivers fluid to the patient when future blood glucose levels are in a patient's target range. The infusion device is capable of suspending and resuming fluid delivery based on future blood glucose levels and a patient's low shutoff threshold. The infusion device suspends fluid delivery when future blood glucose levels falls below the low shutoff threshold. The infusion device resumes fluid delivery when a future blood glucose level is above the low shutoff threshold.
    Type: Application
    Filed: June 21, 2012
    Publication date: October 11, 2012
    Applicant: MEDTRONIC MINIMED, INC.
    Inventors: Andrew C. Hayes, John J. Mastrototaro, Sheldon B. Moberg, John C. Mueller, JR., H. Bud Clark, Mike Charles Vallet Tolle, Gary L. Williams, Bihong Wu, Garry M. Steil
  • Patent number: 8226556
    Abstract: An infusion system is for infusing a fluid into the body of a patient. The infusion system includes at least one sensor for monitoring blood glucose concentration of the patient and an infusion device for delivering fluid to the patient. The sensor produces at least one sensor signal input. The infusion device uses the at least one sensor signal input and a derivative predicted algorithm to determine future blood glucose levels. The infusion device delivers fluid to the patient when future blood glucose levels are in a patient's target range. The infusion device is capable of suspending and resuming fluid delivery based on future blood glucose levels and a patient's low shutoff threshold. The infusion device suspends fluid delivery when future blood glucose levels falls below the low shutoff threshold. The infusion device resumes fluid delivery when a future blood glucose level is above the low shutoff threshold.
    Type: Grant
    Filed: May 6, 2009
    Date of Patent: July 24, 2012
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Andrew C. Hayes, John J. Mastrototaro, Sheldon B. Moberg, John C. Mueller, Jr., H. Bud Clark, Mike Charles Vallet Tolle, Gary L. Williams, Bihong Wu, Garry M. Steil
  • Publication number: 20110282321
    Abstract: A system and method for controlling and monitoring a diabetes-management system through the use of a model that predicts or estimates future dynamic states of glucose and insulin from variables such as insulin delivery or exogenous glucose appearance as well as inherent physiological parameters. The model predictive estimator can be used as an insulin bolus advisor to give an apriori estimate of postprandial glucose for a given insulin delivery profile administered with a known meal to optimize insulin delivery; as a supervisor to monitor the operation of the diabetes-management system; and as a model predictive controller to optimize the automated delivery of insulin into a user's body to achieve a desired blood glucose profile or concentration. Open loop, closed-loop, and semi-closed loop embodiments of the invention utilize a mathematical metabolic model that includes a Minimal Model, a Pump Delivery to Plasma Insulin Model, and a Meal Appearance Rate Model.
    Type: Application
    Filed: June 27, 2011
    Publication date: November 17, 2011
    Applicant: MEDTRONIC MINIMED, INC.
    Inventors: GARRY M. STEIL, Sami S. Kanderian, JR., Martin T. Cantwell, Udo Hoss