Abstract: The present invention provides a transmitted light detection type measurement apparatus for skin fluorescence, which is configured to perform light irradiation and light detection on a reference sample and a measurement target. The apparatus includes a first light source, a second light source, a first optical detector and a second optical detector, a light source switching controller, and an operator.

Abstract: Provided is a reflection detection type measurement method for skin fluorescence. The method includes: irradiating excitation light on a measurement target; detecting a reflected light and a skin fluorescence generated from the measurement target due to the excitation light; irradiating light with a wavelength range of the skin fluorescence on the measurement target; detecting a reflected light generated from the measurement target due to the light with a wavelength range of the skin fluorescence; and calculating a skin fluorescence value of the measurement target by correcting a calculation based on the detected reflected light and skin fluorescence.

Abstract: The present invention relates to a filter switching device for a fluorescence endoscopic television camera system, and more particularly, to a filter switching device for a fluorescence endoscopic television camera system, which selectively transmits light to a detector sensor of a television camera according to the white light condition or the fluorescence condition to diagnose patients using a fluorescence endoscope. The present invention provides a filter switching device for a fluorescence endoscopic television camera system, which is configured to conveniently switch filters according to the rotational movement of the camera head, by inducing a change of magnetic forces according to the rotation of the camera head by magnetic substances disposed therein while maintaining a sealed structure inside the camera head connecting between a fluorescence endoscope and a television camera and thus allowing the frame of the camera head mounted with two types of filter to move upward and downward.

Abstract: The present invention relates to a device for observing a sentinel lymph node (SLN) in a human body. More particularly, the present invention relates to a device for observing an SLN by detecting near-infrared (NIR) fluorescence caused by a fluorescent material such as indocyanine green (ICG) at the SLN and a method for detecting NIR fluorescence at an SLN. Particularly, in the implementation of a composite image obtained by reproducing a fluorescent material such as ICG and NIR fluorescence emitted by excitation light together with a visible light image, it is possible to detect an SLN with high accuracy through a color contrast method and/or a temporal modulation method using an NIR fluorescence image signal and a visible reflection light image signal.

Abstract: The present invention provides a transmitted light detection type measurement apparatus for skin fluorescence, which is configured to perform light irradiation and light detection on a reference sample and a measurement target. The apparatus includes a first light source, a second light source, a first optical detector and a second optical detector, a light source switching controller, and an operator.

Abstract: The present invention provides a reflection detection type measurement apparatus for skin fluorescence, which is configured to perform light irradiation and light detection on a reference sample and a measurement target.

Abstract: Provided is a reflection detection type measurement apparatus for skin fluorescence. The apparatus includes: a first light source irradiating excitation light on a measurement target; a second light source irradiating light of a wavelength different from that of light from the first light source on the measurement target; a first optical detector detecting a reflected light generated from the measurement target due to the excitation light of the first light source; and a second optical detector detecting a skin fluorescence generated from the measurement target due to the excitation light of the first light source, and detecting a reflected light generated from the measurement target due to the excitation light of the second light source. The first optical detector is disposed in an area other than a total reflection area to which the excitation light of the first light source is reflected after irradiating to the measurement target.

Abstract: Provided is a reflection detection type measurement method for skin fluorescence. The method includes: irradiating excitation light on a measurement target; detecting a reflected light and a skin fluorescence generated from the measurement target due to the excitation light; irradiating light with a wavelength range of the skin fluorescence on the measurement target; detecting a reflected light generated from the measurement target due to the light with a wavelength range of the skin fluorescence; and calculating a skin fluorescence value of the measurement target by correcting a calculation based on the detected reflected light and skin fluorescence.

Abstract: The present invention relates to a device for observing a sentinel lymph node (SLN) in a human body. More particularly, the present invention relates to a device for observing an SLN by detecting near-infrared (NIR) fluorescence caused by a fluorescent material such as indocyanine green (ICG) at the SLN and a method for detecting NIR fluorescence at an SLN. Particularly, in the implementation of a composite image obtained by reproducing a fluorescent material such as ICG and NIR fluorescence emitted by excitation light together with a visible light image, it is possible to detect an SLN with high accuracy through a color contrast method and/or a temporal modulation method using an NIR fluorescence image signal and a visible reflection light image signal.

Abstract: The present invention provides a transmitted light detection type measurement apparatus for skin fluorescence, which is configured to perform light irradiation and light detection on a reference sample and a measurement target. The apparatus includes a first light source, a second light source, a first optical detector and a second optical detector, a light source switching controller, and an operator.

Abstract: The present invention relates to a filter switching device for a fluorescence endoscopic television camera system, and more particularly, to a filter switching device for a fluorescence endoscopic television camera system, which selectively transmits light to a detector sensor of a television camera according to the white light condition or the fluorescence condition to diagnose patients using a fluorescence endoscope. The present invention provides a filter switching device for a fluorescence endoscopic television camera system, which is configured to conveniently switch filters according to the rotational movement of the camera head, by inducing a change of magnetic forces according to the rotation of the camera head by magnetic substances disposed therein while maintaining a sealed structure inside the camera head connecting between a fluorescence endoscope and a television camera and thus allowing the frame of the camera head mounted with two types of filter to move upward and downward.

Abstract: Disclosed herein is a light source apparatus for photo-diagnosis and phototherapy. The light source apparatus includes a first light source, a second light source, a light-guide, an interference filter, and a compensation filter. The first light source is non-coherent, and the second light source is coherent. The light-guide delivers light emitted from the first light source and the second light source. The interference filter is disposed on an optical path of the first light source. The compensation filter is disposed between the first light source and the light-guide, and compensates for an output spectrum of the first light source and converts the output spectrum of the first light source into a predetermined reference output spectrum. Here, the light emitted from the second light source is reflected by the interference filter to be incident to the light-guide and the light from the first light source passes through the interference filter at the same time.

Abstract: The present invention provides a transmitted light detection type measurement apparatus for skin fluorescence, which is configured to perform light irradiation and light detection on a reference sample and a measurement target. The apparatus includes a first light source, a second light source, a first optical detector and a second optical detector, a light source switching controller, and an operator.

Abstract: The present invention provides a reflection detection type measurement apparatus for skin fluorescence, which is configured to perform light irradiation and light detection on a reference sample and a measurement target.

Abstract: The present invention provides a fluorescence detection and photodynamic therapy apparatus including: a combined light source unit 10 including a plurality of coherent and non-coherent light sources 11, 12 and 13 configured to irradiate light onto a to-be-observed object while performing continuous illumination; an optical imaging unit 20 configured to form an image of the to-be-observed object 70 and project the image to an image processing/controlling system 34; a multispectral imaging unit 30 including a one-chip multispectral sensor and the image processing/controlling system 34; a blocking filter 40 installed between the to-be-observed object 70 and the one-chip multispectral sensor 32, the blocking filter being configured to block some light reflected off from the to-be-observed object 70 while allowing some light and fluorescent light to pass therethrough; a computer system 50 configured to process, analyze, reproduce and store the image acquired from the multispectral imaging unit 30, and transfer the

Abstract: Disclosed is an improved fluorescent endoscope system having reduced factors that cause errors during diagnosis based on quantitative evaluation of fluorescent intensity for improved accuracy of fluorescent endoscopic diagnosis.

Abstract: The present invention relates, in general, to a fluorescence microscope and method of observing samples using the microscope and, more particularly, to a fluorescence microscope and method of observing samples using the microscope, which can reduce optical noise and obtain images with higher sensitivity, thus obtaining precise information about the density, quantity, location, etc. of a fluorophore, and which can simultaneously process separate images even when a plurality of fluorophores having different excitation and fluorescent wavelength ranges is distributed, thus easily obtaining information about the fluorophores. The fluorescence microscope of the present invention includes an objective lens, and first and third medium units. The first medium unit has a refractive index of n1 to accommodate one or more micro-objects including fluorophores and provide a path of excitation light to excite the fluorophores.

Abstract: This present invention relates to a fluorescence endoscope apparatus, developed for diagnosing various illnesses within a body, especially for diagnosing a tumor inflamed region; and an application method of the same. The purpose of this invention is to enhance the accuracy of the examination. The fluorescence light endoscope apparatus in accordance with the present invention is comprised of an endoscope probe; a multiple light source that provides illumination light or excitation light of short wavelength onto a diagnostic region; a color CCD camera and a high sensitive monochromatic CCD camera placed on the back of an endoscope ocular lens; a reference test sample; a computer; and a monitor.