Patents by Inventor Gary Blackburn

Gary Blackburn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microfluidic devices comprising biochannels
    Publication number: 20050009101
    Abstract: The present invention is directed to a variety of microfluidic devices with configurations including the use of biochannels or microchannels comprising arrays of capture binding ligands to capture target analytes in samples. The invention provides microfluidic cassettes or devices that can be used to effect a number of manipulations on a sample to ultimately result in target analyte detection or quantification.
    Type: Application
    Filed: July 7, 2004
    Publication date: January 13, 2005
    Inventor: Gary Blackburn
  • Binding acceleration techniques for the detection of analytes
    Publication number: 20050003399
    Abstract: The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow electronic detection of the ETM.
    Type: Application
    Filed: April 12, 2004
    Publication date: January 6, 2005
    Inventors: Gary Blackburn, Stephen Creager, Scott Fraser, Bruce Irvine, Thomas Meade, Stephen O'Connor, Robert Terbrueggen, Jost Vielmetter, Thomas Welch
  • Printed circuit boards with monolayers and capture ligands
    Patent number: 6761816
    Abstract: The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow electronic detection of the ETM.
    Type: Grant
    Filed: March 8, 2000
    Date of Patent: July 13, 2004
    Assignee: Clinical Micro Systems, Inc.
    Inventors: Gary Blackburn, Stephen E. Creager, Scott Fraser, Bruce D. Irvine, Thomas J. Meade, Stephen D. O'Connor, Robert H. Terbrueggen, Jost G. Vielmetter, Thomas W. Welch
  • Amplification of nucleic acids with electronic detection
    Patent number: 6686150
    Abstract: The invention relates to compositions and methods useful in the detection of nucleic acids using a variety of amplification techniques, including both signal amplification and target amplification. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the nucleic acid, either directly or indirectly, to allow electronic detection of the ETM using an electrode.
    Type: Grant
    Filed: July 20, 2000
    Date of Patent: February 3, 2004
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Gary Blackburn, Bruce D. Irvine, Jon Faiz Kayyem, Edward Lewis Sheldon, III, Robert H. Terbrueggen
  • Microfluidic devices comprising biochannels
    Publication number: 20030190608
    Abstract: The invention relates to a microfluidic device with microchannels that have separated regions which have a member of a specific binding pair member such as DNA or RNA bound to porous polymer, beads or structures fabricated into the microchannel. The microchannels of the invention are fabricated from plastic and are operatively associated with a fluid propelling component and detector.
    Type: Application
    Filed: May 17, 2001
    Publication date: October 9, 2003
    Inventor: Gary Blackburn
  • Nucleic acid reactions using labels with different redox potentials
    Publication number: 20030143556
    Abstract: The present invention is directed to methods and compositions for the use of electron transfer moieties with different redox potentials to electronically detect nucleic acids, particularly for the electrochemical sequencing of DNA.
    Type: Application
    Filed: April 30, 2002
    Publication date: July 31, 2003
    Inventors: Gary Blackburn, Jon Faiz Kayyem, Chunlin Tao, Changjun Yu
  • Devices and methods for biochip multiplexing
    Publication number: 20020177135
    Abstract: The invention is directed to devices that allow for simultaneous multiple biochip analysis. In particular, the devices are configured to hold multiple cartridges comprising biochips comprising arrays such as nucleic acid arrays, and allow for high throughput analysis of samples.
    Type: Application
    Filed: July 11, 2001
    Publication date: November 28, 2002
    Inventors: Hau H. Doung, Gary Blackburn, Jon F. Kayyem, Stephen D. O'Connor, Gary T. Olsen, Robert Pietri, Nathan Swami, Robert H. Terbrueggen
  • Systems for electrophoretic transport and detection of analytes
    Patent number: 6290839
    Abstract: The invention relates to compositions and methods useful in the electrophoretic transport of target analytes to a detection electrode comprising a self-assembled monolayer (SAM). Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow electronic detection of the ETM.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: September 18, 2001
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Jon Faiz Kayyem, Gary Blackburn, Stephen D. O'Connor
  • Binding acceleration techniques for the detection of analytes
    Patent number: 6264825
    Abstract: The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow electronic detection of the ETM.
    Type: Grant
    Filed: June 23, 1999
    Date of Patent: July 24, 2001
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Gary Blackburn, Stephen E. Creager, Scott Fraser, Bruce D. Irvine, Thomas J. Meade, Stephen D. O'Connor, Robert H. Terbrueggen, Jost G. Vielmetter, Thomas W. Welch