Patents by Inventor Gary K. Steinberg

Gary K. Steinberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL NR1 ES-DERIVED NEURAL STEM CELLS HAVING A NORMAL KARYOTYPE AND USES THEREOF
    Publication number: 20230405054
    Abstract: Compositions and methods are provided relating to NR1 ES-derived neural stem cells. The cells are useful in methods of treatment for an adverse neurologic conditions, including without limitation stoke.
    Type: Application
    Filed: October 11, 2021
    Publication date: December 21, 2023
    Inventor: Gary K. Steinberg
  • Derivation of neural stem cells from embryonic stem cells
    Patent number: 8338176
    Abstract: Provided is a method for the derivation of neural stem cells (NSCs) from embryonic stem cells (ESCs) and the use of the NSCs for treatment of various neural disorders. The NSCs that are derived from the ESCs are tissue-specific multipotent NSCs with a stable growth rate, unlimited self-renewal capacity, and a predictable differentiation profile. Being both non-tumorigenic and engraftable, the NSCs of the present invention have utility in repopulation stroke-damaged tissue. The NSCs of the present invention may be differentiated to produce tyrosine-hydroxylase expressing neurons, which may be used as a source of dopaminergic neurons for subjects suffering from a condition characterized by dopaminergic dysfunction, such as Parkinson's disease.
    Type: Grant
    Filed: July 29, 2008
    Date of Patent: December 25, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Marcel M. Daadi, Gary K. Steinberg
  • ISCHEMIA-INDUCED NEOVASCULARIZATION IS ENHANCED BY hCNS-SC TRANSPLANTATION
    Publication number: 20100196328
    Abstract: The invention provides methods for inducing or enhancing neovascularization following ischemia by transplanting an effective amount of human central nervous system stem cells. The human central nervous system stem cells can be grown as neurospheres or in adherent culture. Also provided are methods for inducing the repair of ischemic tissue in a patient and methods for treating stroke in a patient suffering therefrom.
    Type: Application
    Filed: April 24, 2008
    Publication date: August 5, 2010
    Inventors: Tonya Bliss, Gary K. Steinberg
  • DERIVATION OF NEURAL STEM CELLS FROM EMBRYONIC STEM CELLS AND METHODS OF USE THEREOF
    Publication number: 20090035284
    Abstract: Provided is a method for the derivation of neural stem cells (NSCs) from embryonic stem cells (ESCs) and the use of the NSCs for treatment of various neural disorders. The NSCs that are derived from the ESCs are tissue-specific multipotent NSCs with a stable growth rate, unlimited self-renewal capacity, and a predictable differentiation profile. Being both non-tumorigenic and engraftable, the NSCs of the present invention have utility in repopulation stroke-damaged tissue. The NSCs of the present invention may be differentiated to produce tyrosine-hydroxylase expressing neurons, which may be used as a source of dopaminergic neurons for subjects suffering from a condition characterized by dopaminergic dysfunction, such as Parkinson's disease.
    Type: Application
    Filed: July 29, 2008
    Publication date: February 5, 2009
    Applicant: The Board of Trustees Of The Leland Stanford Junior University
    Inventors: Marcel M. Daadi, Gary K. Steinberg