Abstract: A wellbore screen includes a base pipe including a wall, an inner bore surface and an outer surface, an opening formed through the base pipe wall and a filter cartridge mounted in the opening. In one aspect, the wellbore screen includes an impermeable layer relative to the opening and the impermeable layer may be selected to be substantially impermeable when in a closed position in the opening to passage of fluids through the opening and, the impermeable layer is at least one of (i) selectively openable to permit fluid flow through the opening and (ii) selectively closeable when triggered to close the opening. In another aspect, the opening may include a tapering diameter from one end to the other and the filter cartridge may include an outer diameter formed to reversibly and substantially correspondingly taper relative to the opening to permit a taper lock fit in the opening.

Abstract: A wellbore tubular including: an inner tubular wall; an opening through the inner tubular wall; an outer tubular wall positioned about the inner tubular, the outer tubular wall including an opening therethrough; a chamber between the inner tubular wall and the outer tubular wall; and a chemical treatment material in the chamber and positioned between the opening of the inner tubular wall and the opening of the outer tubular wall. The wellbore tubular may be used in downhole fluid treatment process.

Abstract: A fuel delivery system is disclosed which includes a purge device which comprises a compressor (30) which includes a tank (32) for supplying compressed air to a line (34) which is connected to a fuel line (24). The compressed air is supplied to a point between a fuel tank (22) and a pump (26) to push fuel back into the tank (22) or through the pump (26) then through an injector (20) and back through a return line (28) to the tank so that the fuel line is completely purged of fuel.

Abstract: A wellbore screen includes a base pipe including a wall, an inner bore surface and an outer surface, an opening formed through the base pipe wall and a filter cartridge mounted in the opening. In one aspect, the wellbore screen includes an impermeable layer relative to the opening and the impermeable layer may be selected to be substantially impermeable when in a closed position in the opening to passage of fluids through the opening and, the impermeable layer is at least one of (i) selectively openable to permit fluid flow through the opening and (ii) selectively closeable when triggered to close the opening. In another aspect, the opening may include a tapering diameter from one end to the other and the filter cartridge may include an outer diameter formed to reversibly and substantially correspondingly taper relative to the opening to permit a taper lock fit in the opening.

Abstract: A fuel delivery system for an engine is disclosed which includes an injector (20) and a housing (3) for supporting a fuel injector (20). A regulator (202, 313) is provided for regulating the pressure of fluid in the housing to maintain the pressure at about supply pressure, and the pressure downstream of the regulator at a low pressure so that fuel which passes the regulator is able to evaporate. The evaporated fuel is supplied to a heater (250) to heat the fuel, and the vapour is supplied to a vapour injector (260) for injection into the engine. The passage of the liquid petroleum gas fuel through the housing (3) cools the injector (20) to maintain the fuel in a liquid state, and therefore prevent boiling of the vapour within the injector.

Abstract: A method of measuring an analyte concentration in body fluid. The method includes the use of an analyte measuring device that has an analyte sensing element with a sharpened distal end and further has an indicating electrode covered by an absorbent layer. Also, an electric power, data processing and display device is adapted to mate to and activate the analyte sensing element by applying electric power to it and adapted to receive the raw analyte measurement and to compute and display a refined analyte measurement from the raw analyte measurement. The analyte sensing element is introduced into the animal body, thereby placing the absorbent layer into contact with the body fluid. The absorbent layer becomes saturated with body fluid and the analyte sensing element is removed from the body and is activated to form a raw analyte measurement. Which is used to form and display a refined analyte measurement.

Abstract: A class of [1,8] naphthyridine analogues which are substituted in the 4-position by a substituted phenyl ring. These compounds are ligands for GABAA receptors and useful in the therapy of deleterious mental states such as anxiety.

Abstract: A class of substituted pyrazolo[1,5-d][1,2,4]triazine derivatives, possessing an optionally substituted cycloalkyl, phenyl or heteroaryl substituent at the 7-position, an alkyl group at the 4-position, and a substituted alkoxy moiety at the 2-position, are selective ligands for GABAA receptors, in particular having high affinity for the ?2 and/or ?3 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of disorders of the central nervous system, including anxiety and convulsions.

Abstract: A class of substituted 1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing a fluoro-substituted phenyl ring at the 3-position and a heteroaryl-methoxy moiety at the 6-position, are selective ligands for GABAA receptors, in particular having high affinity for the &agr;2 and/or &agr;3 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of disorders of the central nervous system, including anxiety and convulsions.

Abstract: A class of [1,8] naphthyridine analogues which are substituted in the 4-position by a substituted phenyl ring. These compounds are ligands for GABAA receptors and useful in the therapy of deleterious mental states such as anxiety.

Abstract: A method of measuring an analyte concentration in body fluid. The method includes the use of an analyte measuring device that has an analyte sensing element with a sharpened distal end and further has an indicating electrode covered by an absorbent layer. Also, an electric power, data processing and display device is adapted to mate to and activate the analyte sensing element by applying electric power to it and adapted to receive the raw analyte measurement and to compute and display a refined analyte measurement from the raw analyte measurement. The analyte sensing element is introduced into the animal body, thereby placing the absorbent layer into contact with the body fluid. The absorbent layer becomes saturated with body fluid and the analyte sensing element is removed from the body and is activated to form a raw analyte measurement. Which is used to form and display a refined analyte measurement.

Abstract: A class of substituted 1,2,4-triazolo[4,3b]pyridazine derivatives, possessing a fluoro-substituted phenyl ring at the 3-position and a heteroaryl-methoxy moiety at the 6-position, are selective ligands for GABAA receptors, in particular having high affinity for the &agr;2 and/or &agr;3 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of disorders of the central nervous system, including anxiety and convulsions.

Abstract: 1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing a fluoro-substituted phenyl ring at the 3-position and a heteroaryl-alkoxy moiety at the 6-position, are selective ligands for GABAA receptors, in particular having high affinity for the &agr;2 and/or &agr;3 subunit thereof, are useful in the treatment of anxiety and convulsions.

Abstract: A class of substituted pyrazolo[1,5-d][1,2,4]triazine derivatives, possessing an optionally substituted cycloalkyl, phenyl or heteroaryl substituent at the 7-position, an alkyl group at the 4-position, and a substituted alkoxy moiety at the 2-position, are selective ligands for GABAA receptors, in particular having high affinity for the &agr;2 and/or &agr;3 subunit thereof, and are accordingly of benefit in the treatment and/or prevention of disorders of the central nervous system, including anxiety and convulsions.

Abstract: Compounds according to Formula (I): or a salt or prodrug thereof, have good affinity as ligands for the alpha2 and/or alpha3 subunit of the human GABAA receptor and are useful for treatment of disorders of the central nervous system, including anxiety and convulsions.

Abstract: Substituted triazolo-pyridazine derivative compounds represented by wherein the variables are disclosed herein are selective ligands for GABA-A receptors, particularly for the &agr;2 and/or &agr;3 subunits.

Abstract: Compounds having formula I, or pharmaceutically acceptable salts or prodrugs thereof: ##STR1## are selective agonists of the 5-HT.sub.1D.alpha. receptor and are useful in the treatment of migraine and associated conditions.

Abstract: A class of substituted azetidine, pyrrolidine and piperidine derivatives are selective agonists of 5-HT.sub.1 -like receptors, being potent agonists of the human 5-HT.sub.1D.alpha. receptor subtype whilst possessing at least a 10-fold selective affinity for the 5-HT.sub.1D.alpha. receptor subtype relative to the 5-HT.sub.1D.beta. subtype; they are therefore useful in the treatment and/or prevention of clinical conditions, in particular migraine and associated disorders, for which a subtype-selective agonist of 5-HT.sub.1D receptors is indicated, whilst eliciting fewer side-effects, notably adverse cardiovascular events, than those associated with non-subtype-selective 5-HT.sub.1D receptor agonists.

Abstract: An electrochromic device for use in the field of optical lenses. The device includes a substrate having an expanse and an edge region. A first electrode layer is coated on the expanse and extends substantially across the expanse and into the edge region. An electrochromic layer is coated on the first electrode so that the first electrode layer physically isolates the electrochromic layer from the substrate. A second electrode layer is coated on the electrochromic layer, so that the electrochromic layer physically isolates the second electrode layer from the first electrode layer. A first contact is electrically connected to the first electrode layer. An isolative barrier is coated on the first electrode layer in the edge region. A second contact is electrically connected to the second electrode layer. Alternatively, an isolative channel is formed in the second electrode layer to electrically isolate the first electrode layer from the second electrode layer.

Abstract: An erasable optical data storage medium has a polymer dual recording layer including an expansion layer bonded to a retention layer, each of the layers dyed to selectively absorb light in respective narrow wavelength bands. The retention layer has a glass transition temperature substantially above the glass transition temperature of the expansion layer, and is capable of undergoing substantial viscoelastic shear deformation while below its glass transition temperature. A first laser beam heats the expansion layer causing it to expand and cause viscoelastic deformation in the retention layer while the retention layer is below its glass transition temperature. A second laser beam is used to heat the retention layer above its glass transition temperature and relax the deformation, erasing the medium.