Patents by Inventor Georg Schramm

Georg Schramm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9717691
    Abstract: The present invention relates to a medicament in the form of daily units, which contain an active ingredient combination consisting of a hormone combination with contraceptive action consisting of at least one oestrogen selected from the group consisting of estradiol and ethinyl estradiol and at least one gestagen selected from the group consisting of chlormadinone acetate, 3-?-OH-chlormadinone acetate, 3-?-OH-chlormadinone acetate, 3-?-acetoxy-chlormadinone acetate and 3-?-acetoxy-chlormadinone acetate, and at least one insulin sensitiser and which are combined to provide a dosage form with daily units which only contain an insulin sensitiser as the sole active ingredient, and to the use of this dosage form for preventing or treating pathological disorders caused by polycystic ovary syndrome (PCOS) and for simultaneous contraception.
    Type: Grant
    Filed: June 3, 2010
    Date of Patent: August 1, 2017
    Assignee: RICHTER GEDEON NYRT.
    Inventor: Georg Schramm
  • Patent number: 9278072
    Abstract: The present invention relates to a hormonal contraceptive including 21 to 25 hormone-containing daily units, which contain a combination of ethinyloestradiol in an amount of ?25 ?g and chlormadinone acetate in an amount of ?5 mg, and optionally 7 to 3 hormone-free daily units for oral administration to women.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: March 8, 2016
    Assignee: Richter Gedeon Nyrt.
    Inventors: Janine Klose, Johannes Bartholomäus, Klaus-Michael Wilsmann, Georg Schramm
  • Patent number: 9107840
    Abstract: The present invention relates to a hormonal contraceptive including at least 120 hormone-containing daily units, which contain 5 to 50 ?g of ethinyloestradiol and 1 to 5 mg of chlormadinone acetate, and optionally 7 to 3 hormone-free daily units for uninterrupted oral administration to women.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: August 18, 2015
    Assignee: Richter Gedeon Nyrt.
    Inventors: Georg Schramm, Rainer Henske
  • Publication number: 20140249117
    Abstract: The present invention relates to a medicament, the active ingredient combination of which consists of a retinoid selected from the group consisting of acitretin [9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid], etretinate [ethyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate], isotretinoin [3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid] and tretinoin [3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid] and of a hormone combination with contraceptive action of an oestrogen component and a gestagen component, and to a dosage form consisting of at least 28 daily units, of which the final 7-3 daily units contain only the retinoid as active ingredient and the other daily units also contain the hormone-containing active ingredient combination, and to the use thereof for treating acne, seborrhoea or psoriasis.
    Type: Application
    Filed: May 12, 2014
    Publication date: September 4, 2014
    Applicant: RICHTER GEDEON NYRT.
    Inventors: Georg SCHRAMM, Karl-Heinz OEDEKOVEN
  • Patent number: 8580771
    Abstract: A dosage form for hormonal contraception containing a given number of hormone-containing daily units and a given number of hormone-free daily units for daily, oral administration, where the hormone-containing daily units each contain at most the minimum effective daily amount of folic acid for women and the hormone-free daily units contain at least a multiple of this amount up to the maximum permissible amount of folic acid for women.
    Type: Grant
    Filed: October 6, 2005
    Date of Patent: November 12, 2013
    Assignee: Richter Gedeon Nyrt.
    Inventors: Georg Schramm, Eric-Paul Paques
  • Patent number: 8465763
    Abstract: The present invention relates to the use of 3?-hydroxychlormadinone acetate (17?-acetoxychloropregna-4,6-dien-3?-ol-20-one) and/or 3?-hydroxychlormadinone acetate (17?-acetoxychloropregna-4,6-dien-3?-ol-20-one) for producing a medicament for treating skin, preferably human skin by means of topical application, and to a pharmaceutical or cosmetic composition containing 3?-hydroxychlormadinone acetate and/or 3?-hydroxychlormadinone acetate.
    Type: Grant
    Filed: June 12, 2009
    Date of Patent: June 18, 2013
    Assignee: Richter Gedeon Nyrt.
    Inventors: Georg Schramm, Christa Kneip
  • Patent number: 8361995
    Abstract: The present invention relates to the use of at least one gestagen selected from the group consisting of chlormadinone acetate, 3?-hydroxy-6-chloro-17?-acetoxy-4,6-pregnadien-20-one (3?-hydroxy-chlormadinone acetate) and 3?-hydroxy-6-chloro-17?-acetoxy-4,6-pregnadien-20-one (3?-hydroxy-chlormadinone acetate) as gestagen component and optionally at least one oestrogen selected from the group consisting of ethinyl oestradiol, oestrone, oestriol as oestrogen component and oestradiol to produce a medicament for the treatment and/or prevention of melasma and optionally for simultaneous hormonal contraception or optionally for simultaneous hormone replacement for women.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: January 29, 2013
    Assignee: Richter Gedeon Nyrt.
    Inventor: Georg Schramm
  • Publication number: 20120053160
    Abstract: A dosage form for hormonal contraception containing a specific number of gestagen-containing daily units A and a specific number of gestagen-containing daily units B for uninterrupted, daily, oral administration of daily units A and then immediately subsequently of daily units B, wherein the daily units A in each case contain at most 200 ?g of folic acid and the daily units B contain >200 ?g up to the maximum permissible amount of folic acid for women.
    Type: Application
    Filed: November 7, 2011
    Publication date: March 1, 2012
    Applicant: Gruenenthal GmnH
    Inventors: Georg SCHRAMM, Eric-Paul PAQUES
  • Patent number: 8119620
    Abstract: A dosage form for hormonal contraception containing a specific number of gestagen-containing daily units A and a specific number of gestagen-containing daily units B for uninterrupted, daily, oral administration of daily units A and then immediately subsequently of daily units B, wherein the daily units A in each case contain at most 200 ?g of folic acid and the daily units B contain >200 ?g up to the maximum permissible amount of folic acid for women.
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: February 21, 2012
    Assignee: Gruenenthal GmbH
    Inventors: Georg Schramm, Eric-Paul Paques
  • Patent number: 8097604
    Abstract: The present invention relates to a medicament which contains as the active ingredient combination at least one gestagen with a contraceptive action as the sole hormone component and at least one insulin sensitizer, which medicament is in particular suitable for preventing or treating pathological disorders which are caused by polycystic ovary syndrome (PCOS).
    Type: Grant
    Filed: December 1, 2008
    Date of Patent: January 17, 2012
    Assignee: Gruenenthal GmbH
    Inventor: Georg Schramm
  • Publication number: 20110172197
    Abstract: A dosage form for hormonal contraception containing a given number of hormone-containing daily units and a given number of hormone-free daily units for daily, oral administration, where the hormone-containing daily units each contain at most the minimum effective daily amount of folic acid for women and the hormone-free daily units contain at least a multiple of this amount up to the maximum permissible amount of folic acid for women.
    Type: Application
    Filed: March 23, 2011
    Publication date: July 14, 2011
    Applicant: Grunenthal GmbH
    Inventors: Georg SCHRAMM, Eric-Paul PAQUES
  • Publication number: 20110015161
    Abstract: The present invention relates to a medicament in the form of daily units, which contain an active ingredient combination consisting of a hormone combination with contraceptive action consisting of at least one oestrogen selected from the group consisting of estradiol and ethinyl estradiol and at least one gestagen selected from the group consisting of chlormadinone acetate, 3-?-OH-chlormadinone acetate, 3-?-OH-chlormadinone acetate, 3-?-acetoxy-chlormadinone acetate and 3-?-acetoxy-chlormadinone acetate, and at least one insulin sensitiser and which are combined to provide a dosage form with daily units which only contain an insulin sensitiser as the sole active ingredient, and to the use of this dosage form for preventing or treating pathological disorders caused by polycystic ovary syndrome (PCOS) and for simultaneous contraception.
    Type: Application
    Filed: June 3, 2010
    Publication date: January 20, 2011
    Applicant: GRUENENTHAL GMBH
    Inventor: GEORG SCHRAMM
  • Publication number: 20100063014
    Abstract: The present invention relates to the use of at least one gestagen selected from the group consisting of chlormadinone acetate, 3?-hydroxy-6-chloro-17?-acetoxy-4,6-pregnadien-20-one (3?-hydroxy-chlormadinone acetate) and 3?-hydroxy-6-chloro-17?-acetoxy-4,6-pregnadien-20-one (3?-hydroxy-chlormadinone acetate) as gestagen component and optionally at least one oestrogen selected from the group consisting of ethinyl oestradiol, oestrone, oestriol as oestrogen component and oestradiol to produce a medicament for the treatment and/or prevention of melasma and optionally for simultaneous hormonal contraception or optionally for simultaneous hormone replacement for women.
    Type: Application
    Filed: September 3, 2009
    Publication date: March 11, 2010
    Applicant: GRÜNENTHAL GMBH
    Inventor: GEORG SCHRAMM
  • Publication number: 20090318395
    Abstract: The present invention relates to the use of 3?-hydroxychlormadinone acetate (17?-acetoxychloropregna-4,6-dien-3?-ol-20-one) and/or 3?-hydroxychlormadinone acetate (17?-acetoxychloropregna-4,6-dien-3?-ol-20-one) for producing a medicament for treating skin, preferably human skin by means of topical application, and to a pharmaceutical or cosmetic composition containing 3?-hydroxy-chlormadinone acetate and/or 3?-hydroxychlormadinone acetate.
    Type: Application
    Filed: June 12, 2009
    Publication date: December 24, 2009
    Applicant: GRUNENTHAL GMBH
    Inventors: GEORG SCHRAMM, CHRISTA KNEIP
  • Publication number: 20090312296
    Abstract: The present invention relates to a medicament, the active ingredient combination of which consists of a retinoid selected from the group consisting of acitretin [9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid], etretinate [ethyl 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate], isotretinoin [3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid] and tretinoin [3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid] and of a hormone combination with contraceptive action of an oestrogen component and a gestagen component, and to a dosage form consisting of at least 28 daily units, of which the final 7-3 daily units contain only the retinoid as active ingredient and the other daily units also contain the hormone-containing active ingredient combination, and to the use thereof for treating acne, seborrhoea or psoriasis.
    Type: Application
    Filed: June 12, 2009
    Publication date: December 17, 2009
    Applicant: GRUNENTHAL GMBH
    Inventors: GEORG SCHRAMM, KARL-HEINZ OEDEKOVEN
  • Publication number: 20090118245
    Abstract: The present invention relates to a medicament which contains as the active ingredient combination at least one gestagen with a contraceptive action as the sole hormone component and at least one insulin sensitiser, which medicament is in particular suitable for preventing or treating pathological disorders which are caused by polycystic ovary syndrome (PCOS).
    Type: Application
    Filed: December 1, 2008
    Publication date: May 7, 2009
    Applicant: GRUNENTHAL GMBH
    Inventor: GEORG SCHRAMM
  • Publication number: 20090023694
    Abstract: The present invention relates to an administration form for hormonal contraception consisting of a particular number of hormone-containing daily units, comprising a hormone combination consisting of at least one oestrogen selected from the group comprising ethinyl oestradiol (I) and oestradiol (II) as the oestrogen component, and at least one metabolite of chlormadinone acetate selected from the group comprising 3?-hydroxy-6-chloro-17?-acetoxy-4,6-pregnadien-20-one (3?-hydroxy-chlormadinone acetate), 3?-hydroxy-6-chloro-17?-acetoxy-4,6-pregnadien-2-one (3?-hydroxy-chlormadinone acetate), optionally mixed with chlormadinone acetate and/or 3?-hydroxy-17?-acetoxy-5?-pregnan-20-one and/or 3?-hydroxy-17?-acetoxy-5?-pregnan-20-one as the gestagen component for the uninterrupted, daily, oral administration of the hormone-containing daily units, optionally in combination with 7 to 3 hormone-free daily units.
    Type: Application
    Filed: July 8, 2008
    Publication date: January 22, 2009
    Applicant: GRUNENTHAL GMBH
    Inventors: Georg Schramm, Christa Kneip, Johannes Schneider
  • Publication number: 20080312200
    Abstract: The present invention relates to the use of a hormone combination of ethinyl oestradiol or oestradiol as oestrogen component and at least one metabolite of chlormadinone acetate selected from the group consisting of 3?-hydroxy-6-chloro-17?-acetoxy-4,6-pregnadien-20-one (3?-hydroxychlormadinone acetate), 3?-hydroxy-6-chloro-17?-acetoxy-4,6-pregnadien-20-one (3?-hydroxychlormadinone acetate), 3?-hydroxy-17?-acetoxy-5?-pregnan-20-one and 3?-hydroxy-17?-acetoxy-5?-pregnan-20-one, optionally mixed with chlormadinone acetate as gestagen component for producing a medicament at least for alleviating menstrual cycle-dependent mood swings and optionally for hormonal contraception in women.
    Type: Application
    Filed: July 8, 2008
    Publication date: December 18, 2008
    Applicant: Grunenthal GmbH
    Inventors: Georg Schramm, Christa Kneip
  • Publication number: 20080261934
    Abstract: A dosage form for hormonal contraception containing a specific number of gestagen-containing daily units A and a specific number of gestagen-containing daily units B for uninterrupted, daily, oral administration of daily units A and then immediately subsequently of daily units B, wherein the daily units A in each case contain at most 200 ?g of folic acid and the daily units B contain >200 ?g up to the maximum permissible amount of folic acid for women.
    Type: Application
    Filed: May 9, 2008
    Publication date: October 23, 2008
    Applicant: Gruenenthal GmbH
    Inventors: Georg SCHRAMM, Eric-Paul Paques
  • Publication number: 20060089338
    Abstract: A dosage form for hormonal contraception containing a given number of hormone-containing daily units and a given number of hormone-free daily units for daily, oral administration, where the hormone-containing daily units each contain at most the minimum effective daily amount of folic acid for women and the hormone-free daily units contain at least a multiple of this amount up to the maximum permissible amount of folic acid for women.
    Type: Application
    Filed: October 6, 2005
    Publication date: April 27, 2006
    Inventors: Georg Schramm, Eric-Paul Paques