Patents by Inventor Georg Thierbach

Georg Thierbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020072098
    Abstract: A process for the preparation of L-amino acids, in which the following steps are carried out,
    Type: Application
    Filed: December 8, 2000
    Publication date: June 13, 2002
    Inventors: Petra Ziegler, Lothar Eggeling, Hermann Sahm, Georg Thierbach, Walter Pfefferle
  • Publication number: 20020068335
    Abstract: The present invention provides processes for preparing D-pantothenic acid using Coryneform bacteria having an enhanced pfkA gene.
    Type: Application
    Filed: June 25, 2001
    Publication date: June 6, 2002
    Applicant: DEGUSSA AG
    Inventors: Georg Thierbach, Nicole Dusch
  • Publication number: 20020049305
    Abstract: An isolated polynucleotide comprising a polynucleotide sequence selected from the group consisting of
    Type: Application
    Filed: August 2, 2001
    Publication date: April 25, 2002
    Applicant: DEGUSSA AG
    Inventors: Brigitte Bathe, Bettina Moeckel, Walter Pfefferle, Klaus Huthmacher, Michael Binder, Dieter Greissinger, Georg Thierbach
  • Publication number: 20020048793
    Abstract: An isolated polynucleotide comprising a polynucleotide sequence selected from the group consisting of
    Type: Application
    Filed: August 2, 2001
    Publication date: April 25, 2002
    Applicant: DEGUSSA AG
    Inventors: Brigitte Bathe, Bettina Moeckel, Walter Pfefferle, Klaus Huthmacher, Christian Rueckert, Joern Kalinowski, Alfred Puehler, Michael Binder, Dieter Greissinger, Georg Thierbach
  • Publication number: 20020042104
    Abstract: The invention provides a process for preparing D-pantothenic acid by the fermentation of coryneform bacteria in which bacteria are used in which the nucleotide sequence (pck gene) coding for phosphoenolpyruvate carboxykinase (EC 4.1.1.
    Type: Application
    Filed: May 10, 2001
    Publication date: April 11, 2002
    Inventors: Nicole Dusch, Georg Thierbach
  • Patent number: 6184006
    Abstract: A method for the production of D-pantothenic acid by the fermentation of microorganisms of the family Enterobacteriacae producing D-pantothenic acid which is characterized in that strains are used which a) Contain the plasmid pFV31 and/or pFV202 and that b) A panD gene and optionally other nucleotide sequences coding for aspartate-1-decarboxylase are enhanced, especially overexpressed in these microorganisms, c) The pantothenic acid is enriched in the medium or in the cells of the microorganisms and d) The pantothenic acid formed is isolated.
    Type: Grant
    Filed: May 26, 1999
    Date of Patent: February 6, 2001
    Assignee: Degussa-Hüls Aktiengesellschaft
    Inventors: Mechthild Rieping, Georg Thierbach, Walter Pfefferle, Nicole Dusch, Jorn Kalinowski, Alfred Puhler
  • Patent number: 6177264
    Abstract: The invention discloses three polynucleotide sequences for the fermentative production of D-pantothenic acid. These polynucleotide sequences are genes named panB, encoding a ketopantoate hydroxymethyltransferase, panC, encoding pantothenate synthase, and ilvD, encoding dihydroxy-acid dehydratase. The genes panB and panC are found on the same operon, panBC, while the gene ilvD is found in a separate operon. These genes can be used separately or together to enhance the production of D-pantothenic acid in microorganisms, especially in Corynebacterium.
    Type: Grant
    Filed: May 26, 1999
    Date of Patent: January 23, 2001
    Assignees: Degussa-Huls Aktiengesellschaft, Forschunszentrum Julich GmbH
    Inventors: Lothar Eggeling, Georg Thierbach, Hermann Sahm
  • Patent number: 6171845
    Abstract: The invention relates to a process for the preparation and improvement of D-pantothenic acid-producing microorganisms by amplification of nucleotide sequences which code for ketopantoate reductase, in particular the panE gene, individually or in combination with one another, and optionally additionally of the ilvC gene, the microorganisms containing these nucleotide sequences, and a process for the preparation of D-pantothenic acid comprising fermentation of these microorganisms, concentration of pantothenic acid in the medium or in the cells of the microorganisms, and isolation of the D-pantothenic acid.
    Type: Grant
    Filed: October 12, 1999
    Date of Patent: January 9, 2001
    Assignee: Degussa-Huls AG
    Inventors: Frank Elischweski, Jorn Kalinowski, Alfred Puhler, Nicole Dusch, Jurgen Dohmen, Mike Farwick, Georg Thierbach
  • Patent number: 5175108
    Abstract: The present invention relates to new plasmids isolated from Corynebacterium glutamicum, plasmid pGA1 and pGA2, which are compatible with one another. In addition, the present invention relates to recombinant plasmids and to plasmid vectors (shuttle vectors) containing the new plasmids. The plasmids and plasmid vectors of the present invention are suitable for use with genetic engineering to improve bacteria strains.
    Type: Grant
    Filed: August 27, 1991
    Date of Patent: December 29, 1992
    Assignee: Degussa Aktiengesellschaft
    Inventors: Frank Bachmann, Hans J. Kutzner, Hans Sonnen, Georg Thierbach, Petra-Sabine Kautz, Alfred Puhler, Andreas Schaefer