Patents by Inventor George M. Whitesides
George M. Whitesides has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10704537Abstract: A soft robot device includes at least a first thermoplastic layer and a second thermoplastic layer, wherein at least one layer is comprised of an extensible thermoplastic material; at least one layer is an inextensible layer; and at least one layer comprises a pneumatic network, wherein the pneumatic network is configured to be in fluidic contact with a pressurizing source, wherein the first and second thermoplastic layers are thermally bonded to each other.Type: GrantFiled: May 29, 2018Date of Patent: July 7, 2020Assignee: President and Fellows of Harvard CollegeInventors: Jason Ming Ting, Alok Suryavamsee Tayi, Bobak Mosadegh, George M. Whitesides
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Patent number: 10689044Abstract: A pneumatically powered, fully untethered mobile soft robot is described. Composites consisting of silicone elastomer, polyaramid fabric, and hollow glass microspheres were used to fabricate a sufficiently large soft robot to carry the miniature air compressors, battery, valves, and controller needed for autonomous operation. Fabrication techniques were developed to mold a 0.65 meter long soft body with modified Pneumatic network actuators capable of operating at the elevated pressures (up to 138 kPa) required to actuate the legs of the robot and hold payloads of up to 8 kg. The soft robot is safe to handle, and its silicone body is innately resilient to a variety of adverse environmental conditions including snow, puddles of water, direct (albeit limited) exposure to flames, and the crushing force of being run over by an automobile.Type: GrantFiled: June 30, 2015Date of Patent: June 23, 2020Assignee: President and Fellows of Harvard CollegeInventors: Michael T. Tolley, Robert F. Shepherd, Bobak Mosadegh, Robert J. Wood, George M. Whitesides
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Patent number: 10639801Abstract: An actuator includes a plurality of chambers comprised of an extensible material, the chambers having interior side walls and exterior walls, wherein at least a portion of the interior side wall is separated from an interior side wall of an adjacent chamber; and a strain limiting base; and a channel that fluidically interconnects the plurality of chambers, wherein the interior walls are configured to be more compliant than the exterior walls.Type: GrantFiled: August 20, 2014Date of Patent: May 5, 2020Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGEInventors: Bobak Mosadegh, Robert F. Shepherd, George M. Whitesides
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Patent number: 10584724Abstract: A soft actuator is described, including: a rotation center having a center of mass; a plurality of bucklable, elastic structural components each comprising a wall defining an axis along its longest dimension, the wall connected to the rotation center in a way that the axis is offset from the center of mass in a predetermined direction; and a plurality of cells each disposed between two adjacent bucklable, elastic structural components and configured for connection with a fluid inflation or deflation source; wherein upon the deflation of the cell, the bucklable, elastic structural components are configured to buckle in the predetermined direction. A soft actuating device including a plurality of the soft actuators and methods of actuation using the soft actuator or soft actuating device disclosed herein are also described.Type: GrantFiled: November 17, 2017Date of Patent: March 10, 2020Assignee: President and Fellows of Harvard CollegeInventors: Dian Yang, George M. Whitesides
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Patent number: 10576643Abstract: A soft robotic device with one or more sensors is described. The sensor may be embedded in the soft body of the soft robotic device, attached to the soft body of the soft robotic device, or otherwise linked to the soft body of the soft robotic device.Type: GrantFiled: August 21, 2015Date of Patent: March 3, 2020Assignee: President and Fellows of Harvard CollegeInventors: Joshua Aaron Lessing, George M. Whitesides, Ramses V. Martinez, Dian Yang, Bobak Mosadegh, Kevin C. Galloway, Firat Güder, Alok Suryavamsee Tayi
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Patent number: 10548745Abstract: A finger actuator, includes a plurality of fluidically interconnected inflatable chambers, wherein each chamber comprises outer walls having an embedded extensible layer selected to constrain radial expansion and freestanding inner walls; and an inextensible layer connected to the chambers at a base of the chambers, the inextensible layer comprising a flexible polymer and having an embedded inextensible layer that extends along the length of the finger actuator.Type: GrantFiled: June 26, 2017Date of Patent: February 4, 2020Assignee: President and Fellows of Harvard CollegeInventors: Bobak Mosadegh, Brandon Grant Gerberich, George M. Whitesides
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Patent number: 10465723Abstract: A soft robotic device includes a flexible body having a width, a length and a thickness, wherein the thickness is at least 1 mm, the flexible body having at least one channel disposed within the flexible body, the channel defined by upper, lower and side walls, wherein at least one wall is strain limiting; and a pressurizing inlet in fluid communication with the at least one channel, the at least one channel positioned and arranged such that the wall opposite the strain limiting wall preferentially expands when the soft robotic device is pressurized through the inlet.Type: GrantFiled: October 10, 2016Date of Patent: November 5, 2019Assignee: President and Fellows of Harvard CollegeInventors: Filip Ilievski, Xin Chen, Aaron D. Mazzeo, George M. Whitesides, Robert F. Shepherd, Ramses V. Martinez, Won Jae Choi, Sen Wai Kwok, Stephen A. Morin, Adam Stokes, Zhihong Nie
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Patent number: 10436768Abstract: The disclosed methods use a multi-phase system to separate samples according to the density of an analyte of interest. The method uses a multi-phase system that comprises two or more phase-separated solutions and a phase component such as a surfactant or polymer. The density of the analyte of interest differs from the densities of the rest of the sample. The density of the analyte of interest is substantially the same as one or more phases. Thus, when the sample is introduced to the multi-phase system, the analyte of interest migrates to the phase having the same density as the analyte of interest, passing through one or more phases sequentially.Type: GrantFiled: November 29, 2017Date of Patent: October 8, 2019Assignee: President and Fellows of Harvard CollegeInventors: Charles R. Mace, Ashok A. Kumar, Dyann F. Wirth, George M. Whitesides
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Patent number: 10418145Abstract: An elastically-deformable, conductive composite using elastomers and conductive fibers and simple fabrication procedures is provided. Conductive elastomeric composites offer low resistance to electrical current and are elastic over large (>25%) extensional strains. They can be easily interfaced/built into structures fabricated from elastomeric polymers.Type: GrantFiled: June 5, 2015Date of Patent: September 17, 2019Assignee: President and Fellows of Harvard CollegeInventors: Joshua Aaron Lessing, Stephen A. Morin, George M. Whitesides
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Patent number: 10406698Abstract: Apparatus, systems, and methods for providing modular soft robots are disclosed. In particular, the disclosed modular soft robot can include a flexible actuator having a plurality of molded flexible units. Each molded flexible unit can include a mechanical connector configured to provide a physical coupling to another molded flexible unit, and the plurality of molded flexible units are arranged to form an embedded fluidic channel. The modular soft robot can also include an inlet coupled to the embedded fluidic channel, where the inlet is configured to receive pressurized or depressurized fluid to inflate or deflate a portion of the flexible actuator, thereby causing an actuation of the flexible actuator.Type: GrantFiled: July 18, 2013Date of Patent: September 10, 2019Assignee: President and Fellows of Harvard CollegeInventors: Stephen A. Morin, Sen Wai Kwok, Robert F. Shepherd, George M. Whitesides
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Patent number: 10385886Abstract: A soft buckling linear actuator is described, including: a plurality of substantially parallel bucklable, elastic structural components each having its longest dimension along a first axis; and a plurality of secondary structural components each disposed between and bridging two adjacent bucklable, elastic structural components; wherein every two adjacent bucklable, elastic structural components and the secondary structural components in-between define a layer comprising a plurality of cells each capable of being connected with a fluid inflation or deflation source; the secondary structural components from two adjacent layers are not aligned along a second axis perpendicular to the first axis; and the secondary structural components are configured not to buckle, the bucklable, elastic structural components are configured to buckle along the second axis to generate a linear force, upon the inflation or deflation of the cells. Methods of actuation using the same are also described.Type: GrantFiled: September 13, 2017Date of Patent: August 20, 2019Assignee: President and Fellows of Harvard CollegeInventors: Dian Yang, George M. Whitesides
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Patent number: 10299779Abstract: A surgical device for displacement of organs within a body cavity for providing at least visual access to a selected site includes an expandable bladder, wherein the elasticity of the bladder varies across the surface of the bladder, said variation in elasticity selected to provide a predetermined, non-spherical shape when expanded; and a valve on the proximal end on the inflatable bladder for introduction of a pressurizing gas into the soft bladder.Type: GrantFiled: October 20, 2014Date of Patent: May 28, 2019Assignee: President and Fellows of Harvard CollegeInventors: Robert F. Shepherd, George M. Whitesides, Bobak Mosadegh
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Patent number: 10302586Abstract: A class of devices enabled by ionic conductors is highly stretchable, fully transparent to light of all colors, biocompatible or biodegradable, and capable of operation at frequencies beyond 10 kilohertz and voltages above 10 kilovolts. These devices enabled by ionic conductors can be used as large strain actuators, full-range loudspeakers, as strain or pressure sensors and as stretchable interconnects. The electromechanical transduction is achieved without electrochemical reaction. When large stretchability and high optical transmittance are required, the ionic conductors have lower sheet resistance than all existing electronic conductors.Type: GrantFiled: April 10, 2014Date of Patent: May 28, 2019Assignee: President and Fellows of Harvard CollegeInventors: Jeong Yun Sun, Christoph Matthias Keplinger, Zhigang Suo, George M. Whitesides
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Patent number: 10261223Abstract: Exemplary method and system for providing a diffractive configuration in an optical arrangement are provided. For example, a material can be provided with at least one patterned surface having a very high aspect ratio. The material can be connected with at least one portion of a waveguide arrangement using a pre-polymer adhesive composition. Further, the pre-polymer adhesive composition can be caused to polymerize so as to form the diffractive configuration which at least approximately replicates a structure or at least one feature of the patterned surface.Type: GrantFiled: January 30, 2015Date of Patent: April 16, 2019Assignees: Canon USA, Inc., The General Hospital CorporationInventors: Guillermo J Tearney, Dongkyun Kang, Mitsuhiro Ikuta, George M. Whitesides, Ramses V. Martinez
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Patent number: 10260533Abstract: A modular pneumatic robotic actuator, including a first elongated hollow structure and a second elongated hollow structure connected to each other at a moveable joint; an inflatable bladder comprised of an elastomeric material disposed at the said joint and immobilized between the first and second hollow structures, wherein the said inflatable bladder inflates preferentially away from the joint; and a restraining membrane comprised of an elastomeric material disposed over the bladder and connecting the first and second hollow structures, wherein the said restraining membrane is relaxed when the bladder is deflated.Type: GrantFiled: August 1, 2017Date of Patent: April 16, 2019Assignee: President and Fellows of Harvard CollegeInventors: Yanina Shevchenko, George M. Whitesides, Adam Stokes, Gabrielle Compton, Alex Nemiroski
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Publication number: 20190091858Abstract: Systems and methods for providing flexible robotic actuators are disclosed. Some embodiments of the disclosed subject matter include a soft robot capable of providing a radial deflection motions; a soft tentacle actuator capable of providing a variety of motions and providing transportation means for various types of materials; and a hybrid robotic system that retains desirable characteristics of both soft robots and hard robots. Some embodiments of the disclosed subject matter also include methods for operating the disclosed robotic systems.Type: ApplicationFiled: May 25, 2018Publication date: March 28, 2019Inventors: Stephen A. MORIN, Robert F. SHEPHERD, Adam STOKES, Filip ILIEVSKI, Ramses V. MARTINEZ, Jamie L. BRANCH, Carina R. FISH, Lihua JIN, Rui M.D. NUNES, Zhigang SUO, George M. WHITESIDES
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Patent number: 10233910Abstract: Some embodiments of the disclosed subject matter includes a laminated robotic actuator. The laminated robotic actuator includes a strain-limiting layer comprising a flexible, non-extensible material in the form of a sheet or thin film, a flexible inflatable layer in the form of a thin film or sheet in facing relationship with the strain-limiting layer, wherein the inflatable layer is selectively adhered to the strain-limiting layer, and wherein a portion of an un-adhered region between the strain-limiting layer and the inflatable layer defines a pressurizable channel, and at least one fluid inlet in fluid communication with the pressurizable channel. The first flexible non-extensible material has a stiffness that is greater than the stiffness of the second flexible elastomeric material and the flexible elastomer is non-extensible under actuation conditions.Type: GrantFiled: November 28, 2016Date of Patent: March 19, 2019Assignee: President and Fellows of Harvard CollegeInventors: Aaron D. Mazzeo, Stephen A. Morin, Robert F. Shepherd, George M. Whitesides, William B. Kalb
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Publication number: 20190072552Abstract: An assay device and method are described. The assay may involve immobilizing a binding partner (e.g., an antigen or antibody) for an analyte to be detected (e.g., an antibody or antigen) on a portion of a surface of a microfluidic chamber; passing a fluid sample over the surface and allowing the analyte to bind to the binding partner; allowing a metal colloid, e.g., a gold-conjugated antibody, to associate with the bound analyte; flowing a metal solution, e.g., a silver solution, over the surface such as to form an opaque metallic layer; and detecting the presence of said metallic layer, e.g., by visual inspection or by measuring light transmission through the layer, conductivity or resistance of the layer, or metal concentration in the metal solution after flowing the metal solution over the surface.Type: ApplicationFiled: September 20, 2018Publication date: March 7, 2019Applicant: President and Fellows of Harvard CollegeInventors: Samuel K. Sia, Vincent Linder, Babak Parviz, Adam Carlyn Siegel, George M. Whitesides
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Publication number: 20190030710Abstract: A soft robot having an integrated electrical component includes an expandable or collapsible body, the body comprising an inlet that is configured to communicate with a fluid source and a flexible strain limited layer secured to a portion of the expandable or collapsible body, wherein the strain limited layer includes at least one electrical component.Type: ApplicationFiled: May 7, 2018Publication date: January 31, 2019Inventors: Joshua Aaron LESSING, Ramses V. MARTINEZ, Alok Suryavamsee TAYI, Jason Ming TING, George M. WHITESIDES
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Publication number: 20190024644Abstract: A soft robot device includes at least a first thermoplastic layer and a second thermoplastic layer, wherein at least one layer is comprised of an extensible thermoplastic material; at least one layer is an inextensible layer; and at least one layer comprises a pneumatic network, wherein the pneumatic network is configured to be in fluidic contact with a pressurizing source, wherein the first and second thermoplastic layers are thermally bonded to each other.Type: ApplicationFiled: May 29, 2018Publication date: January 24, 2019Inventors: Jason Ming TING, Alok Suryavamsee TAYI, Bobak MOSADEGH, George M. WHITESIDES