Patents by Inventor George Tidmarsh

George Tidmarsh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160074465
    Abstract: The present disclosure relates to the use of angiotensin II in therapeutic methods for the treatment of hypotension, especially catecholamine-resistant hypotension.
    Type: Application
    Filed: July 8, 2015
    Publication date: March 17, 2016
    Inventor: George Tidmarsh
  • Patent number: 9205098
    Abstract: Methods for the treatment of cancer are described. In particular, methods for treatment of cancer comprising administration of glufosfamide alone or in combination with another anticancer agent are disclosed.
    Type: Grant
    Filed: October 23, 2012
    Date of Patent: December 8, 2015
    Assignee: Threshold Pharmaceuticals
    Inventor: George Tidmarsh
  • Publication number: 20140329747
    Abstract: The present disclosure relates to the use of angiotensin II in therapeutic methods for the treatment of renal failure, especially renal failure associated with cirrhosis.
    Type: Application
    Filed: April 28, 2014
    Publication date: November 6, 2014
    Applicant: La Jolla Pharmaceutical Company
    Inventor: George Tidmarsh
  • Publication number: 20130011476
    Abstract: Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. The compositions comprise a famotidine core having a reduced or minimal surface area surrounded by a layer of ibuprofen. In some embodiments, the ibuprofen is in direct physical contact with the famotidine.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 10, 2013
    Inventors: Jerry Xu, George Tidmarsh
  • Publication number: 20130011475
    Abstract: Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. The compositions comprise a famotidine core having a reduced or minimal surface area surrounded by a layer of ibuprofen. In some embodiments, the ibuprofen is in direct physical contact with the famotidine.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 10, 2013
    Inventors: Jerry Xu, George Tidmarsh
  • Patent number: 8318683
    Abstract: Methods for the treatment of cancer are described. In particular, methods for treatment of cancer comprising administration of glufosfamide alone or in combination with another anticancer agent are disclosed.
    Type: Grant
    Filed: February 4, 2005
    Date of Patent: November 27, 2012
    Assignee: Threshold Pharmaceuticals, Inc.
    Inventor: George Tidmarsh
  • Publication number: 20120156292
    Abstract: Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. The compositions comprise a famotidine core having a reduced or minimal surface area surrounded by a layer of ibuprofen. In some embodiments, the ibuprofen is in direct physical contact with the famotidine.
    Type: Application
    Filed: February 23, 2012
    Publication date: June 21, 2012
    Inventors: Jerry Xu, George Tidmarsh
  • Publication number: 20120156291
    Abstract: Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. The compositions comprise a famotidine core having a reduced or minimal surface area surrounded by a layer of ibuprofen. In some embodiments, the ibuprofen is in direct physical contact with the famotidine.
    Type: Application
    Filed: February 23, 2012
    Publication date: June 21, 2012
    Inventors: Jerry Xu, George Tidmarsh
  • Publication number: 20110311637
    Abstract: A method for administration of ibuprofen to a subject in need of ibuprofen treatment is provided, in which an oral dosage form comprising a therapeutically effective amount of ibuprofen and a therapeutically effective amount of famotidine is administered three times per day.
    Type: Application
    Filed: August 25, 2011
    Publication date: December 22, 2011
    Inventors: George Tidmarsh, Barry L. Golombik, Puneet Sharma
  • Publication number: 20110311636
    Abstract: A method for administration of ibuprofen to a subject in need of ibuprofen treatment is provided, in which an oral dosage form comprising a therapeutically effective amount of ibuprofen and a therapeutically effective amount of famotidine is administered three times per day.
    Type: Application
    Filed: August 25, 2011
    Publication date: December 22, 2011
    Inventors: George Tidmarsh, Barry L. Golombik, Puneet Sharma
  • Publication number: 20110313009
    Abstract: The present invention generally relates to unit dosage forms of naproxen and H2-receptor antagonists, comprising an immediate-release formulation of naproxen; an immediate-release formulation of an H2-receptor antagonist, and a delayed-burst release formulation of an H2-receptor antagonist.
    Type: Application
    Filed: July 17, 2009
    Publication date: December 22, 2011
    Inventors: George Tidmarsh, Leah Appel
  • Patent number: 8067033
    Abstract: Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. The compositions comprise a famotidine core having a reduced or minimal surface area surrounded by a layer of ibuprofen. In some embodiments, the ibuprofen is in direct physical contact with the famotidine.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: November 29, 2011
    Assignee: Horizon Pharma USA, Inc.
    Inventors: Jerry Xu, George Tidmarsh
  • Patent number: 8067451
    Abstract: A method for administration of ibuprofen to a subject in need of ibuprofen treatment is provided, in which an oral dosage form comprising a therapeutically effective amount of ibuprofen and a therapeutically effective amount of famotidine is administered three times per day.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: November 29, 2011
    Assignee: Horizon Pharma USA, Inc.
    Inventors: George Tidmarsh, Barry L. Golombik, Puneet Sharma
  • Publication number: 20110182909
    Abstract: Glufosfamide administered in combination with other chemotherapeutic agents is useful in cancer treatment.
    Type: Application
    Filed: December 22, 2005
    Publication date: July 28, 2011
    Applicant: Threshold Pharmaceuticals, Inc.
    Inventor: George Tidmarsh
  • Publication number: 20100297224
    Abstract: The present invention generally relates to pharmaceutical unit dosage forms of NSAIDs and H2-receptor antagonists, in which the H2-receptor antagonist is formulated so as to be released in a sustained manner over a predetermined period of time so as to maintain gastric pH above a desired level for a duration of time. The NSAID may then be formulated for immediate release. The pharmaceutical unit dosage forms may be administered to subjects susceptible to the development of NSAID induced gastric and/or duodenal ulcers, as the sustained release H2-receptor antagonist is formulated so as to maintain the gastric environment above the pH levels where NSAID-induced ulceration typically occurs.
    Type: Application
    Filed: August 29, 2007
    Publication date: November 25, 2010
    Applicant: Horizon Therapeutics, Inc.
    Inventors: George Tidmarsh, Barry L. Golombik
  • Publication number: 20090264484
    Abstract: A method for administration of ibuprofen to a subject in need of ibuprofen treatment is provided, in which an oral dosage form comprising a therapeutically effective amount of ibuprofen and a therapeutically effective amount of famotidine is administered three times per day.
    Type: Application
    Filed: June 24, 2009
    Publication date: October 22, 2009
    Applicant: Horizon Therapeutics, Inc.
    Inventors: George Tidmarsh, Barry L. Golombik, Puneet Sharma
  • Publication number: 20090247480
    Abstract: Methods for the treatment of cancer are described. In particular, methods for treatment of cancer comprising administration of glufosfamide alone or in combination with another anticancer agent are disclosed.
    Type: Application
    Filed: February 4, 2005
    Publication date: October 1, 2009
    Inventor: George Tidmarsh
  • Patent number: 7560230
    Abstract: The level of one or more glucose transporters in a sample containing cancer cells is measured and compared to a reference value to determine whether the cancer is susceptible to treatment with an anti-cancer agent comprising glucose or glucose analog that is transported into the cancer by a glucose transporter.
    Type: Grant
    Filed: March 4, 2004
    Date of Patent: July 14, 2009
    Assignee: Threshold Pharmaceuticals, Inc.
    Inventor: George Tidmarsh
  • Publication number: 20090142393
    Abstract: Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. The compositions comprise a famotidine core having a reduced or minimal surface area surrounded by a layer of ibuprofen. In some embodiments, the ibuprofen is in direct physical contact with the famotidine.
    Type: Application
    Filed: November 26, 2008
    Publication date: June 4, 2009
    Applicant: Horizon Therapeutics, Inc.
    Inventors: Jerry Xu, George Tidmarsh
  • Publication number: 20080063706
    Abstract: A method for administration of ibuprofen to a subject in need of ibuprofen treatment is provided, in which an oral dosage form comprising a therapeutically effective amount of ibuprofen and a therapeutically effective amount of famotidine is administered three times per day.
    Type: Application
    Filed: July 17, 2007
    Publication date: March 13, 2008
    Applicant: Horizon Therapeutics, Inc.
    Inventors: George Tidmarsh, Barry Golombik, Puneet Sharma