Patents by Inventor George Tsu-Chih Chiu

George Tsu-Chih Chiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210238541
    Abstract: The present disclosure relates to a novel method for rapid preparation of three dimensional (3D) spheroids/organoids, and the 3D spheroids/organoids prepared by the novel method.
    Type: Application
    Filed: December 1, 2020
    Publication date: August 5, 2021
    Applicant: Purdue Research Foundation
    Inventors: Bumsoo Han, George Tsu-Chih Chiu, Cih Cheng
  • Publication number: 20210231646
    Abstract: A ?PAD may include a substrate comprising a substrate. The ?PAD may further include a non-polar material printed on a surface of the substrate such that a portion the surface is exposed. The exposed portion may include a receiving area, a plurality of test areas, and a plurality of channels disposed between the receiving area and the test areas. The ?PAD may further include colorimetric sensors respectively positioned in the test areas. The channel regions may be configured to receive an analyte solution from the receiving area and direct the analyte solution to the colorimetric sensors. A system may perform image processing on captured images of the ?PAD to provide multiplexed analysis of analyte solutions applied to the ?PAD.
    Type: Application
    Filed: January 28, 2021
    Publication date: July 29, 2021
    Applicant: Purdue Research Foundation
    Inventors: Lia Antoaneta Stanciu-Gregory, Jan P. Allebach, George Tsu-Chih Chiu, Lixby S. Diaz, Min Zhao
  • Patent number: 11060998
    Abstract: This present disclosure relates to sensors capable of sensing mass, stiffness, and chemical or biological substances. More specifically, this disclosure provides the design and implementation of a piecewise-linear resonator realized via diode- and integrated circuit-based feedback electronics and a quartz crystal resonator. The proposed system is fabricated and characterized, and the creation and selective placement of the bifurcation points of the overall electromechanical system is demonstrated by tuning the circuit gains. The demonstrated circuit operates around at least 1 MHz.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: July 13, 2021
    Assignee: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, George Tsu-Chih Chiu, Nikhil Bajaj
  • Patent number: 11027484
    Abstract: Three-dimensional (3D) printed fluoropolymer-based energetic compositions are made using 3D printing methods. The 3D printed fluoropolymer-based energetic compositions comprise a fluoropolymer and a reactive metal or metal oxide. The total weight percentage of the fluoropolymer and the reactive metal or metal oxide is 70-100% of the 3D printed fluoropolymer-based energetic composition, and the weight percentage of the reactive metal or metal oxide is 5-85 wt % of the total weight of the 3D printed fluoropolymer-based energetic material. The 3D printed fluoropolymer-based energetic material has a thickness of at least 200 ?m.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: June 8, 2021
    Assignee: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, George Tsu-Chih Chiu, Ibrahim Emre Gunduz, Trevor John Fleck, Allison Kelly Murray, Steven Forrest Son
  • Patent number: 10948489
    Abstract: A method of detecting a substance, wherein the method includes functionalizing a plurality of sensors, wherein the functionalizing the plurality of sensors comprises depositing a first material using a piezoelectrically actuated pipette system, wherein the first material includes a polymer, a receptor, and a solvent, wherein the solvent comprises dimethylformamide. The method further includes evaporating a solution of the first material wherein a residue after the evaporation comprises a functionalized chemical. Additionally, the method includes introducing a control material to a first set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system. Further, the method includes introducing a test material to a second set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system, wherein the test material comprises an analyte.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: March 16, 2021
    Assignee: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, Eric A. Nauman, Mackenzie Tweardy, Michael Wadas, Allison Kelly Murray, George Tsu-Chih Chiu, Nikhil Bajaj
  • Publication number: 20210046701
    Abstract: This disclosure generally relates to methods and apparatus for 3D printing of highly viscous materials, especially to high amplitude ultrasonic vibration facilitated lower temperature 3D printing of highly viscous materials with a viscosity of at least 1000 Pa·s.
    Type: Application
    Filed: November 3, 2020
    Publication date: February 18, 2021
    Applicant: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, Ibrahim Emre Gunduz, Steven Forrest Son, George Tsu-Chih Chiu
  • Publication number: 20210041387
    Abstract: The present disclosure relates to a novel composite film configured for CO2 sensing, and the method of making and using the novel composite film. The novel composite film comprises a carbon nanotube film and a CO2 absorbing layer deposited on the carbon nanotube film, wherein the CO2 absorbing layer comprises a mixture of a branched polyethylenimine, a polyethylene glycol, and poly[1-(4-vinylbenzyl)-3-methylimidazolium tetrafluoroborate] of formula I: wherein n ranges from 10-300.
    Type: Application
    Filed: August 6, 2020
    Publication date: February 11, 2021
    Applicant: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, George Tsu-Chih Chiu, Bryan W Boudouris, Nikhil Bajaj, Allison Kelly Murray, Zachary A Siefker, Xikang Zhao
  • Publication number: 20200398479
    Abstract: The present disclosure relates to three-dimensional (3D) printed fluoropolymer-based energetic compositions and 3D printing methods for making the 3D printed fluoropolymer-based energetic compositions.
    Type: Application
    Filed: September 2, 2020
    Publication date: December 24, 2020
    Applicant: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, George Tsu-Chih Chiu, Ibrahim E. Gunduz, Trevor J. Fleck, Allison K. Murray, Steven F. Son
  • Patent number: 10870234
    Abstract: This disclosure generally relates to methods and apparatus for 3D printing of highly viscous materials, especially to high amplitude ultrasonic vibration facilitated lower temperature 3D printing of highly viscous materials with a viscosity of at least 1000 Pa·s.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: December 22, 2020
    Assignee: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, Ibrahim Emre Gunduz, Steven Forrest Son, George Tsu-Chih Chiu
  • Publication number: 20200222898
    Abstract: Multi-well collapsible basket arrays and methods for their use with high throughput culture and histology analysis of spheroids and organoids. Such a collapsible basket array includes a collapsible cellular array structure having multiple cells and connectors that interconnect adjacent pairs of the cells to cause the collapsible cellular array structure to collapse from an expanded configuration to a collapsed configuration in which the connectors are partially wrapped around perimeters or circumferences of the cells, whereby the collapsible cellular array structure is expandable to acquire an expanded configuration capable of individually aligning the cells thereof with wells of a well plate. The collapsible basket array further includes inserts individually mountable to the cells of the collapsible cellular array structure, with each insert including a permeable basket with pores sized to retain spheroids or organoids within the basket.
    Type: Application
    Filed: January 13, 2020
    Publication date: July 16, 2020
    Inventors: Bumsoo Han, George Tsu-Chih Chiu, Thomas Heinrich Siegmund, Michael Linnes, Yument Wu, Matthew Tyler Short
  • Publication number: 20200064310
    Abstract: This present disclosure relates to sensors capable of sensing mass, stiffness, and chemical or biological substances. More specifically, this disclosure provides the design and implementation of a piecewise-linear resonator realized via diode- and integrated circuit-based feedback electronics and a quartz crystal resonator. The proposed system is fabricated and characterized, and the creation and selective placement of the bifurcation points of the overall electromechanical system is demonstrated by tuning the circuit gains. The demonstrated circuit operates around at least 1 MHz.
    Type: Application
    Filed: December 4, 2018
    Publication date: February 27, 2020
    Applicant: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, George Tsu-Chih Chiu, Nikhil Bajaj
  • Publication number: 20190283319
    Abstract: This disclosure generally relates to methods and apparatus for 3D printing of highly viscous materials, especially to high amplitude ultrasonic vibration facilitated lower temperature 3D printing of highly viscous materials with a viscosity of at least 1000 Pa·s.
    Type: Application
    Filed: November 7, 2017
    Publication date: September 19, 2019
    Applicant: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, Ibrahim Emre Gunduz, Steven Forrest Son, George Tsu-Chih Chiu
  • Publication number: 20190030789
    Abstract: The present disclosure relates to three-dimensional (3D) printed fluoropolymer-based energetic compositions and 3D printing methods for making the 3D printed fluoropolymer-based energetic compositions.
    Type: Application
    Filed: March 14, 2018
    Publication date: January 31, 2019
    Applicant: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, George Tsu-Chih Chiu, Ibrahim E. Gunduz, Trevor J. Fleck, Allison K. Murray, Steven F. Son
  • Publication number: 20190025296
    Abstract: A method of detecting a substance, wherein the method includes functionalizing a plurality of sensors, wherein the functionalizing the plurality of sensors comprises depositing a first material using a piezoelectrically actuated pipette system, wherein the first material includes a polymer, a receptor, and a solvent, wherein the solvent comprises dimethylformamide. The method further includes evaporating a solution of the first material wherein a residue after the evaporation comprises a functionalized chemical. Additionally, the method includes introducing a control material to a first set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system. Further, the method includes introducing a test material to a second set of sensors of the plurality of sensors using the piezoelectrically actuated pipette system, wherein the test material comprises an analyte.
    Type: Application
    Filed: July 19, 2018
    Publication date: January 24, 2019
    Applicant: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, Eric A. Nauman, Mackenzie Tweardy, Michael Wadas, Allison Kelly Murray, George Tsu-Chih Chiu, Nikhil Bajaj
  • Patent number: 10072969
    Abstract: A device and method for sensing including a sensor having a functional surface layer located to interact with a material to be sensed, the sensor having an output that produces a signal responsive one or more of inertia, stiffness, acceleration, pressure, radiation, chemical compounds, and biological compounds; and further including electronics including: an input coupled to the sensor to receive a first signal therefrom; and a non-linearity provider that applies one or more non-linear operations to the input signal to generate a non-linear second signal.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: September 11, 2018
    Assignee: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, George Tsu-Chih Chiu, Nikhil Bajaj, Andrew Burke Sabater
  • Publication number: 20180180466
    Abstract: A device and method for sensing including a sensor having a functional surface layer located to interact with a material to be sensed, the sensor having an output that produces a signal responsive one or more of inertia, stiffness, acceleration, pressure, radiation, chemical compounds, and biological compounds; and further including electronics including: an input coupled to the sensor to receive a first signal therefrom; and a non-linearity provider that applies one or more non-linear operations to the input signal to generate a non-linear second signal.
    Type: Application
    Filed: February 7, 2018
    Publication date: June 28, 2018
    Applicant: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, George Tsu-Chih Chiu, Nikhil Bajaj, Andrew Burke Sabater
  • Patent number: 9927287
    Abstract: A device and method for sensing including a sensor having a functional surface layer located to interact with a material to be sensed, the sensor having an output that produces a signal responsive one or more of inertia, stiffness, acceleration, pressure, radiation, chemical compounds, and biological compounds; and further including electronics including: an input coupled to the sensor to receive a first signal therefrom; and a non-linearity provider that applies one or more non-linear operations to the input signal to generate a non-linear second signal.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: March 27, 2018
    Assignee: Purdue Research Foundation
    Inventors: Jeffrey Frederick Rhoads, George Tsu-Chih Chiu, Nikhil Bajaj, Andrew Burke Sabater
  • Publication number: 20160290855
    Abstract: A device and method for sensing including a sensor having a functional surface layer located to interact with a material to be sensed, the sensor having an output that produces a signal responsive one or more of inertia, stiffness, acceleration, pressure, radiation, chemical compounds, and biological compounds; and further including electronics including: an input coupled to the sensor to receive a first signal therefrom; and a non-linearity provider that applies one or more non-linear operations to the input signal to generate a non-linear second signal.
    Type: Application
    Filed: December 17, 2015
    Publication date: October 6, 2016
    Inventors: Jeffrey Frederick Rhoads, George Tsu-Chih Chiu, Nikhil Bajaj, Andrew Burke Sabater
  • Patent number: 9014578
    Abstract: Control parameters of a printing device are optimized using a process model to reduce a process tone reproduction curve (TRC) error between a process TRC and a desired TRC. Tone-corrected halftone levels for the printing device are generated using a sensor model to reduce a printing device TRC error between a TRC of the printing device and the desired TRC, based on color patches printed by the printing device using the control parameters as have been optimized, as measured by one or more sensors of the printing device.
    Type: Grant
    Filed: August 15, 2010
    Date of Patent: April 21, 2015
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: YanFu Kuo, Chao-Lung Yang, George Tsu-Chih Chiu, Yuehwern Yih, Jan Allebach, Dennis Alan Abramsohn
  • Publication number: 20130114965
    Abstract: Control para met of a printing device are optimized using a process model to reduce a process tone reproduction curve (TRC) error between a process TRC and a desired TRC. Tone-corrected halftone levels for the printing device are generated using a sensor model to reduce a printing device TRC error between a TRC of the printing device and the desired TRC, based on color patches printed by the printing device using the control parameters as have been optimized, as measured by one or more sensors of the printing device.
    Type: Application
    Filed: August 15, 2010
    Publication date: May 9, 2013
    Inventors: YanFu Kuo, Chao-Lung Yang, George Tsu-Chih Chiu, Yuehwern Yih, Jan Allebach, Dennis Alan Abramsohn