Patents by Inventor George Verlaan

George Verlaan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200253239
    Abstract: The invention relates to the field of protein-dense liquid nutritional compositions for use in the treatment and/or prevention of a condition linked to loss of muscle mass and/or strength. Provided is a heat-treated liquid high-protein composition comprising at least 10 g of protein per 100 ml of the composition, wherein at least 40 wt. % of the protein is micellar casein and at least 10 wt. % of the protein is hydrolysed whey protein having a degree of hydrolysation of at least 5%, and wherein the weight ratio of micellar casein to hydrolysed whey protein is in the range of 40:60 to 90:10, for use in any one or more of the following: a) preventing or reducing coagulation in the upper gastro-intestinal tract; b) increasing the rate of gastric emptying; c) enhancing protein digestion; d) increasing the blood serum concentration of free essential amino acids, preferably leucine, in a subject.
    Type: Application
    Filed: April 29, 2020
    Publication date: August 13, 2020
    Inventors: Pauline Elisabeth Antoinette SMULDERS, Renate Antonia GANZEVLES, George VERLAAN, Marieke Henriƫtte SCHOEMAKER
  • Patent number: 10045999
    Abstract: The invention relates to the use of an anabolic amino acid derivative stimulus acting in combination with vitamin D for the manufacture of a medicament or nutritional composition for the prevention and/or treatment of a loss of any one of muscle mass, muscle strength, muscle function, and physical function, or any combination thereof, in a mammal.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: August 14, 2018
    Assignee: N. V. Nutricia
    Inventors: Marion-Eve Adeline Jourdan, Yvette Charlotte Luiking, George Verlaan, Sovianne Ter Borg
  • Patent number: 9961932
    Abstract: The invention pertains to the use of a composition comprising per serving between 50-300 kcal; between 10 g and 35 g proteinaceous matter; and at least 2.5 microgram vitamin D, for the manufacture of a nutritional product for (a) the treatment or prevention of muscle mass decrease, (b) stimulation of muscle mass increase; or (d) stimulating muscle mass preservation, in obese or overweight adults of at least 40 years of age participating in a weight loss program. The inventors surprisingly found that nutritional supplementation with a low-caloric composition rich in protein, particularly whey protein and leucine, compared to an iso-caloric control supplement without protein, synergistically leads to preservation of muscle mass during a weight loss program involving a hypocaloric diet and a resistance exercise program in overweight/obese older adult.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: May 8, 2018
    Assignee: N.V. Nutricia
    Inventors: Peter Johan Marie Weijs, Johan De Vogel, George Verlaan, Marion Jourdan
  • Publication number: 20160128372
    Abstract: The invention pertains to the use of a composition comprising per serving between 50-300 kcal; between 10 g and 35 g proteinaceous matter; and at least 2.5 microgram vitamin D, for the manufacture of a nutritional product for (a) the treatment or prevention of muscle mass decrease, (b) stimulation of muscle mass increase; or (d) stimulating muscle mass preservation, in obese or overweight adults of at least 40 years of age participating in a weight loss program. The inventors surprisingly found that nutritional supplementation with a low-caloric composition rich in protein, particularly whey protein and leucine, compared to an iso-caloric control supplement without protein, synergistically leads to preservation of muscle mass during a weight loss program involving a hypocaloric diet and a resistance exercise program in overweight/obese older adult.
    Type: Application
    Filed: June 10, 2013
    Publication date: May 12, 2016
    Applicant: N.V. Nutricia
    Inventors: Peter Johan Marie WEIJS, Johan DE VOGEL, George VERLAAN, Marion JOURDAN
  • Publication number: 20150290223
    Abstract: The invention relates to the use of an anabolic amino acid derivative stimulus acting in combination with vitamin D for the manufacture of a medicament or nutritional composition for the prevention and/or treatment of a loss of any one of muscle mass, muscle strength, muscle function, and physical function, or any combination thereof, in a mammal.
    Type: Application
    Filed: June 25, 2015
    Publication date: October 15, 2015
    Inventors: Marion-Eve Adeline Jourdan, Yvette Charlotte Luiking, George Verlaan, Sovianne Ter Borg
  • Patent number: 8846759
    Abstract: The present invention relates to the use of a low-caloric high-protein nutritional composition for use in the prevention or treatment of a disease or condition in a mammal, which involves muscle decline, as well as to specific low-caloric high-protein nutritional compositions for stimulating muscle protein synthesis in a mammal.
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: September 30, 2014
    Assignee: N.V. Nutricia
    Inventors: Yvette Charlotte Luiking, George Verlaan, Marion Jourdan
  • Patent number: 8835396
    Abstract: This invention discloses a method and compositions for treatment or prevention of pulmonary hypertension in a mammal. Representative mammals include humans and horses. The invention further relates to supplements especially beneficial in preventing or stopping the progression of pulmonary hypertension. The supplements include ribose and folate. Additional nutrients include omega-3 fatty acids and gamma-linolenic acid.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: September 16, 2014
    Assignee: Bioenergy, Inc.
    Inventors: George Verlaan, John A. St. Cyr
  • Publication number: 20130210780
    Abstract: The invention relates to the use of an anabolic amino acid derivative stimulus acting in combination with vitamin D for the manufacture of a medicament or nutritional composition for the prevention and/or treatment of a loss of any one of muscle mass, muscle strength, muscle function, and physical function, or any combination thereof, in a mammal.
    Type: Application
    Filed: July 6, 2011
    Publication date: August 15, 2013
    Applicant: N. V. NUTRICIA
    Inventors: Marion-Eve Adeline Jourdan, Yvette Charlotte Luiking, George Verlaan, Sovianne Ter Borg
  • Publication number: 20130203658
    Abstract: The present invention relates to the use of a low-caloric high-protein nutritional composition for use in the prevention or treatment of a disease or condition in a mammal, which involves muscle decline, as well as to specific low-caloric high-protein nutritional compositions for stimulating muscle protein synthesis in a mammal.
    Type: Application
    Filed: December 23, 2010
    Publication date: August 8, 2013
    Applicant: N. V. Nutricia
    Inventors: Yvette Charlotte Luiking, George Verlaan, Marion Jourdan
  • Publication number: 20090082249
    Abstract: The present invention relates to a nutritional product for HIV patients that are not on Highly Active Antiretroviral Therapy. More specifically the invention relates to a nutritional composition comprising oligosaccharides. This invention also relates to the manufacture of a nutritional supplement for use in HIV patients.
    Type: Application
    Filed: April 19, 2006
    Publication date: March 26, 2009
    Applicant: N.V. Nutricia
    Inventors: Johan Garssen, Eric Alexander Franciscus van Tol, Johannes Wilhelmus Christina Jben, George Verlaan
  • Publication number: 20080193589
    Abstract: The invention relates to a fluid that can be used for preventing or treating hypohydration and the secondary consequences thereof. The fluid comprises one or more carbohydrates and minerals and is further is characterized by a low osmolarity. The invention further relates to the use of such a fluid for medical, dietetic and other applications.
    Type: Application
    Filed: April 18, 2008
    Publication date: August 14, 2008
    Applicant: N. V. Nutricia
    Inventors: George VERLAAN, Robert Johan Joseph Hageman, Rudolf Leonardus Lodewijk Smeets
  • Publication number: 20080171720
    Abstract: The present invention relates to a nutritional product for HIV patients. More specifically the invention relates to a nutritional composition that provides carefully selected nutritional ingredients including oligosaccharides and cysteine and/or a source of cysteine specifically supporting HIV patients with nutritionally related symptoms. This invention also relates to the manufacture of a nutritional supplement for use in HIV patients.
    Type: Application
    Filed: April 19, 2006
    Publication date: July 17, 2008
    Inventors: Johan Garssen, Eric Alexander Franciscus Van Tol, Johannes Wilhelmus Christina Sijben, George Verlaan
  • Publication number: 20080161398
    Abstract: The invention relates to a formulation in the form of a pharmaceutical composition, a food product, a feed product or a dietary supplement, comprising leucine and protein in specific amounts. Consumption of a formulation according to the invention has a very positive effect on the generation of muscle tissue and is therefore particularly useful for organisms wherein an anabolic response is desired.
    Type: Application
    Filed: October 16, 2007
    Publication date: July 3, 2008
    Applicant: Nutricia N.V.
    Inventors: George Verlaan, Rudolf Leonardus Lodewijk Smeets, Robert Reese Wolfe
  • Publication number: 20080146514
    Abstract: This invention discloses a method and compositions for treatment or prevention of pulmonary hypertension in a mammal. Representative mammals include humans and horses. The invention further relates to supplements especially beneficial in preventing or stopping the progression of pulmonary hypertension. The supplements include ribose and folate. Additional nutrients include omega-3 fatty acids and gamma linoleic acid.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 19, 2008
    Inventors: George Verlaan, John A. St. Cyr
  • Publication number: 20080146579
    Abstract: The invention pertains to a method and compositions for treatment or prevention of chronic pulmonary dysfunction in a patient.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 19, 2008
    Inventors: Erwin Peke MEIJER, George Verlaan, Maarteen Anne Hoijer
  • Patent number: 7375089
    Abstract: The invention relates to a fluid that can be used for preventing or treating hypohydration and the secondary consequences thereof. The fluid comprises one or more carbohydrates and minerals and is further characterized by a low osmolarity. The invention further relates to the use of such a fluid for medical, dietetic and other applications.
    Type: Grant
    Filed: October 30, 2003
    Date of Patent: May 20, 2008
    Assignee: N.V. Nutricia
    Inventors: George Verlaan, Robert Johan Joseph Hageman, Rudolf Leonardus Lodewijk Smeets
  • Patent number: 7288570
    Abstract: The invention relates to a formulation in the form of a pharmaceutical composition, a food product, a feed product or a dietary supplement, comprising leucine and protein in specific amounts. Consumption of a formulation according to the invention has a very positive effect on the generation of muscle tissue and is therefore particularly useful for organisms wherein an anabolic response is desired.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: October 30, 2007
    Assignee: Nutricia N.V.
    Inventors: George Verlaan, Rudolf Leonardus Lodewijk Smeets, Robert Reese Wolfe
  • Patent number: 7214386
    Abstract: The present invention relates to a method for the prevention and/or treatment of overweight in mammals. More particularly the invention is concerned with such a method comprising the enteral administration to a mammal of a preparation comprising an effective amount of a combination of dill or an isolate thereof and one or more components capable of stimulating in vivo lipolysis. Suitable examples of components capable of stimulating in vivo lipolysis include methylxanthines, adrenergic amines, Paullinia cupana or an isolate thereof, Zingziber officinale or an isolate thereof, Camellia sinensis or an isolate thereof, Ilex paraguayiensis or an isolate thereof. Another aspect of the invention relates to a solid or semi-solid unit dosage, preferably selected from the group consisting of tablets, pills, microparticles, microspheres, suppositories, capsules, caplets and the like, that is suitable for enteral unitary administration to human subjects and other mammals comprising: a.
    Type: Grant
    Filed: March 11, 2003
    Date of Patent: May 8, 2007
    Assignee: N.V. Nutricia
    Inventors: Rene John Raggers, George Verlaan
  • Publication number: 20050287204
    Abstract: There is provided a nutritional or pharmaceutical composition comprising a protein fraction containing L-serine and an energy metabolism precursor wherein the composition is free of glycine or if glycine is present within the composition, the weight ratio of L-serine: glycine after hydrolysis of the composition is of more than 2.7:1, which composition provides an effective creatine response within mammals muscle and methylation reaction capacity of organisms.
    Type: Application
    Filed: June 19, 2003
    Publication date: December 29, 2005
    Inventors: Robert Hageman, George Verlaan
  • Publication number: 20040122097
    Abstract: The invention relates to a formulation in the form of a pharmaceutical composition, a food product, a feed product or a dietary supplement, comprising leucine and protein in specific amounts. Consumption of a formulation according to the invention has a very positive effect on the generation of muscle tissue and is therefore particularly useful for organisms wherein an anabolic response is desired.
    Type: Application
    Filed: December 20, 2002
    Publication date: June 24, 2004
    Applicant: Nutricia N.V.
    Inventors: George Verlaan, Rudolf Leonardus Lodewijk Smeets, Robert Reese Wolfe