Patents by Inventor Gerald H. Franz

Gerald H. Franz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6469228
    Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein (or a portion of a transposase protein), The isolated transposable elements or the isolated DNA sequences being characterized by the ability to hybridize to the DNA sequence of Minos 1 under stringent hybridization conditions. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable are useful in methods for the stable introduction of a DNA sequence of interest into a eukaryotic cell. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the Tc-1 family of transposable elements.
    Type: Grant
    Filed: May 9, 1994
    Date of Patent: October 22, 2002
    Assignee: Minos Biosystems
    Inventors: Charalambos Savakis, Gerald H. Franz, Athanasios Loukeris
  • Publication number: 20020026650
    Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein (or a portion of a transposase protein). The isolated transposable elements or the isolated DNA sequences being characterized by the ability to hybridize to the DNA sequence of Minos 1 under stringent hybridization conditions. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable are useful in methods for the stable introduction of a DNA sequence of interest into a eukaryotic cell. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the Tc-1 family of transposable elements.
    Type: Application
    Filed: May 9, 1994
    Publication date: February 28, 2002
    Inventors: CHARALAMBOS SAVAKIS, GERALD H. FRANZ, ATHANASIOS LOUKERIS
  • Patent number: 6225121
    Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein (or a portion of a transposase protein). The isolated transposable elements or the isolated DNA sequences being characterized by the ability to hybridize to the DNA sequence of Minos-1. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable are useful in methods for the stable introduction of a DNA sequence of interest into a cell. The invention further relates to transgenic animals, gene tagging and insertional mutagenesis produced by such methods. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the Tc-1 family of transposable elements.
    Type: Grant
    Filed: April 27, 1998
    Date of Patent: May 1, 2001
    Assignee: Institute of Molecular Biology and Biotechnology/FORTH
    Inventors: Charalambos Savakis, Gerald H. Franz, Athanasios Loukeris, Apostolos G. Klinakis
  • Patent number: 6159717
    Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein (or a portion of a transposase protein). The isolated transposable elements or the isolated DNA sequences being characterized by the ability to hybridize to the DNA sequence of Minos-1. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable are useful in methods for the stable introduction of a DNA sequence of interest into a cell. The invention further relates to transgenic animals produced by such methods. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the Tc-1 family of transposable elements.
    Type: Grant
    Filed: November 18, 1998
    Date of Patent: December 12, 2000
    Assignee: Institute for Molecular Biology and Biotechnology/Forth
    Inventors: Charalambos Savakis, Gerald H. Franz
  • Patent number: 5840865
    Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein (or a portion of a transposase protein). The isolated transposable elements or the isolated DNA sequences being characterized by the ability to hybridize to the DNA sequence of Minos-1. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable are useful in methods for the stable introduction of a DNA sequence of interest into a cell. The invention further relates to transgenic animals produced by such methods. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the Tc-1 family of transposable elements.
    Type: Grant
    Filed: September 20, 1995
    Date of Patent: November 24, 1998
    Assignee: Institute of Molecular Biology and Biotechnology/FORTH
    Inventors: Charalambos Savakis, Gerald H. Franz, Athanasios Loukeris
  • Patent number: 5348874
    Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein (or a portion of a transposase protein). The isolated transposable elements or the isolated DNA sequences being characterized by the ability to hybridize to the DNA sequence of Minos 1 under stringent hybridization conditions. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable are useful in methods for the stable introduction of a DNA sequence of interest into a eukaryotic cell. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the Tc-1 family of transposable elements.
    Type: Grant
    Filed: September 14, 1992
    Date of Patent: September 20, 1994
    Assignee: Institute for Molecular Biology and Biotechnology/FORTH
    Inventors: Charalambos Savakis, Gerald H. Franz, Athanasios Loukeris