Patents by Inventor Gerard A. Ateshian

Gerard A. Ateshian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210196509
    Abstract: The presently disclosed subject matter provides techniques for inducing collagen cross-linking in human tissue, such as cartilage, by inducing ionization of the water contained in the tissue to produce free radicals that induce chemical cross-linking in the human tissue. In an embodiment, a femtosecond laser operates at sufficiently low laser pulse energy to avoid optical breakdown of the tissue being treated. In an embodiment, the femtosecond laser operates in the infrared frequency range.
    Type: Application
    Filed: February 23, 2021
    Publication date: July 1, 2021
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Sinisa VUKELIC, Gerard A. ATESHIAN
  • Publication number: 20210187165
    Abstract: Treatment systems and methods are disclosed that may be used to strengthen cartilage. The disclosed subject matter includes description of this advantage and associated experimental results. The systems and methods employ ultrafast laser-based treatment to induce crosslinks into the collagen network of the tissue media without the addition of a chemical agent. The system and related methods may also be used for other purposes discussed herein.
    Type: Application
    Filed: December 15, 2020
    Publication date: June 24, 2021
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Sinisa VUKELIC, Gerard A. ATESHIAN, Chao WANG, Krista M. DURNEY
  • Patent number: 10722370
    Abstract: A customized allograft that is bendable and suitable for allo-grafting of an articular joint, including the thumb.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: July 28, 2020
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Melvin P. Rosenwasser, Gerard A. Ateshian, Clark T. Hung, Brian K. Jones
  • Publication number: 20190246907
    Abstract: The present application discloses methods, devices, and systems for generating spatially-resolved quantification of cross-linking in cartilage based on Raman scattering of excitation light. The examples presented demonstrate that the method provides a discriminating power sufficient to distinguish early onset of osteo-arthritis even before a patient is symptomatic.
    Type: Application
    Filed: June 10, 2017
    Publication date: August 15, 2019
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Sinisa VUKELIC, Gerard A. ATESHIAN
  • Publication number: 20190175349
    Abstract: A customized allograft that is bendable and suitable for allo-grafting of an articular joint, including the thumb.
    Type: Application
    Filed: February 21, 2019
    Publication date: June 13, 2019
    Inventors: Melvin P. Rosenwasser, Gerard A. Ateshian, Clark T. Hung, Brian K. Jones
  • Patent number: 10251751
    Abstract: A customized allograft that is bendable and suitable for allo-grafting of an articular joint, including the thumb.
    Type: Grant
    Filed: March 11, 2015
    Date of Patent: April 9, 2019
    Assignee: The Trustees of Columbia University In The City of New York
    Inventors: Melvin P. Rosenwasser, Gerard A. Ateshian, Clark T. Hung, Brian K. Jones
  • Publication number: 20170056181
    Abstract: A customized allograft that is bendable and suitable for allo-grafting of an articular joint, including the thumb.
    Type: Application
    Filed: March 11, 2015
    Publication date: March 2, 2017
    Inventors: Melvin P. Rosenwasser, Gerard A. Ateshian, Clark T. Hung, Brian K. Jones
  • Publication number: 20140091491
    Abstract: Implants for resurfacing or repairing one or more articular cartilage bearing surfaces of a biological organism include an engineered tissue and a biocompatible porous substrate secured to the engineered tissue for attaching the implant to a native bone of the biological organism. The engineered tissue includes a scaffold containing a biocompatible material, and a plurality of living chondrocytes supported by the scaffold. Methods for culturing chondrocytes for incorporation into a biocompatible implant are provided. A bioreactor for producing functional cartilaginous tissue from a cell-seeded scaffold and a system for producing functional cartilaginous tissue are also provided.
    Type: Application
    Filed: December 12, 2013
    Publication date: April 3, 2014
    Applicants: The Trustees of Columbia University in the City of New York, THE CURATORS OF THE UNIVERSITY OF MISSOURI
    Inventors: Clark T. Hung, Gerard A. Ateshian, Eric G. Lima, James L. Cook, Li Ming Bian
  • Patent number: 8608801
    Abstract: Implants for resurfacing or repairing one or more articular cartilage bearing surfaces of a biological organism include an engineered tissue and a biocompatible porous substrate secured to the engineered tissue for attaching the implant to a native bone of the biological organism. The engineered tissue includes a scaffold containing a biocompatible material, and a plurality of living chondrocytes supported by the scaffold. Methods for culturing chondrocytes for incorporation into a biocompatible implant are provided. A bioreactor for producing functional cartilaginous tissue from a cell-seeded scaffold and a system for producing functional cartilaginous tissue are also provided.
    Type: Grant
    Filed: July 6, 2009
    Date of Patent: December 17, 2013
    Assignees: The Trustees of Columbia University in the City of New York, The Curators of the University of Missouri
    Inventors: Clark T. Hung, Gerard A. Ateshian, Eric G. Lima, James L. Cook, Li Ming Bian
  • Publication number: 20100036492
    Abstract: Implants for resurfacing or repairing one or more articular cartilage bearing surfaces of a biological organism include an engineered tissue and a biocompatible porous substrate secured to the engineered tissue for attaching the implant to a native bone of the biological organism. The engineered tissue includes a scaffold containing a biocompatible material, and a plurality of living chondrocytes supported by the scaffold. Methods for culturing chondrocytes for incorporation into a biocompatible implant are provided. A bioreactor for producing functional cartilaginous tissue from a cell-seeded scaffold and a system for producing functional cartilaginous tissue are also provided.
    Type: Application
    Filed: July 6, 2009
    Publication date: February 11, 2010
    Applicants: THE CURATORS OF THE UNIVERSITY OF MISSOURI, The Trustees of Columbia University in the City of New York
    Inventors: Clark T. Hung, Gerard A. Ateshian, Eric G. Lima, James L. Cook, Li Ming Bian
  • Publication number: 20060036331
    Abstract: This invention pertains to materials and methods relating to the biological fixation of one tissue type to another different tissue type, i.e., the fixation of cartilage to bone. A scaffold apparatus for osteochondral tissue engineering is described. The apparatus comprises regions of varying matrices which provide a functional interface between multiple tissue types. Further, a method for preparing the scaffold apparatus is provided. Methods for treating osteochondral tissue injury and cartilage degeneration using the scaffold apparatus are also described. In addition, a method for evaluating cell-mediated and scaffold-related parameters of development and maintenance of multiple tissue zones in vitro is described.
    Type: Application
    Filed: March 4, 2005
    Publication date: February 16, 2006
    Inventors: Helen Lu, Jie Jiang, Clark Hung, X. Guo, Gerard Ateshian
  • Patent number: 6459948
    Abstract: A joint prosthesis for attachment to a bone of a patient, comprising an anchor with a head surface and a stem for attachment to an end of the bone, the head surface having an anatomically accurate shape.
    Type: Grant
    Filed: October 8, 1999
    Date of Patent: October 1, 2002
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Gerard A. Ateshian, Van C. Mow, Robert J. Pawluk, Melvin P. Rosenwasser
  • Patent number: 6126690
    Abstract: A joint prosthesis for attachment to a bone of a patient, comprising an anchor with a head surface and a stem for attachment to an end of the bone, the head surface having an anatomically accurate shape.
    Type: Grant
    Filed: July 3, 1996
    Date of Patent: October 3, 2000
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Gerard A. Ateshian, Van C. Mow, Robert J. Pawluk, Melvin P. Rosenwasser