Patents by Inventor Gerard Kaiko

Gerard Kaiko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND USES OF INFLAMMATORY BOWEL DISEASE BIOMARKERS
    Publication number: 20230313305
    Abstract: Among the various aspects of the present disclosure is the provision of methods of diagnosing and treating inflammatory bowel disease (IBD) including ulcerative colitis (UC) or Crohn's disease (CD). In particular, the present disclosure provides in part a panel of IBD biomarkers useful in diagnosing and making treatment decisions. In addition, the present disclosure provides methods of treating IBD with a plasminogen activator inhibitor-1(PAI-1) inhibitor or tissue plasminogen activator (tPA).
    Type: Application
    Filed: March 16, 2023
    Publication date: October 5, 2023
    Inventors: Thaddeus Stappenbeck, Gerard Kaiko, Ta-Chiang Liu
  • Compositions comprising desaminotyrosine and uses thereof to enhance type I interferon stimulation
    Patent number: 11058653
    Abstract: The disclosure provides compositions comprising desaminotyrosine and methods of use thereof in enhancing type I interferon stimulation, epithelial proliferation, and treatment of inflammatory bowel disease.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: July 13, 2021
    Assignee: Washington University
    Inventors: Thaddeus Stappenbeck, Ashley Steed, Gerard Kaiko, George Christophi
  • METHODS AND USES OF INFLAMMATORY BOWEL DISEASE BIOMARKERS
    Publication number: 20200165677
    Abstract: Among the various aspects of the present disclosure is the provision of methods of diagnosing and treating inflammatory bowel disease (IBD) including ulcerative colitis (UC) or Crohn's disease (CD). In particular, the present disclosure provides in part a panel of IBD biomarkers useful in diagnosing and making treatment decisions. In addition, the present disclosure provides methods of treating IBD with a plasminogen activator inhibitor-1 (PAI-1) inhibitor or tissue plasminogen activator (tPA).
    Type: Application
    Filed: July 18, 2018
    Publication date: May 28, 2020
    Inventors: Thaddeus Stappenbeck, Gerard Kaiko, Ta-Chiang Liu
  • COMPOSITIONS COMPRISING DESAMINOTYROSINE AND USES THEREOF TO ENHANCE TYPE I INTERFERON STIMULATION
    Publication number: 20190274983
    Abstract: The disclosure provides compositions comprising desaminotyrosine and methods of use thereof in enhancing type I interferon stimulation, epithelial proliferation, and treatment of inflammatory bowel disease.
    Type: Application
    Filed: October 26, 2017
    Publication date: September 12, 2019
    Applicant: Washington University
    Inventors: Thaddeus Stappenbeck, Ashley Steed, Gerard Kaiko, George Christophi