Patents by Inventor Gerd Ascher

Gerd Ascher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6063917
    Abstract: A process for the production of a compound of formula ##STR1## wherein R.sup.a denotes hydrogen or silyl;R.sup.b denotes a group of formula --OR.sup.e, whereinR.sup.e denotes hydrogen or alkyl; andR.sup.c and R.sup.d together denote a bond;in free form or in salt form,which process comprises the step of spitting, in the presence of ozone, the double bond in position 3 of the ring structure of a compound of formula III ##STR2## wherein R.sub.2 and R.sub.3 are the same or different and independently of each other denote hydrogen or an organic group, and X.sup.- denotes the anion of an inorganic or organic acid and optionally silylating the amine group in position 7 of the ring system.
    Type: Grant
    Filed: September 30, 1998
    Date of Patent: May 16, 2000
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventors: Gerd Ascher, Johannes Ludescher, Hubert Sturm, Josef Wieser
  • Patent number: 6034237
    Abstract: 3-Imino-cephalosporin derivatives of formula II ##STR1## wherein Y denotes alkyl, aryl or heterocyclyl; and R.sup.a and R.sup.d denote hydrogen or a silyl group; in free form or in salt form, and methods of preparation.
    Type: Grant
    Filed: September 30, 1998
    Date of Patent: March 7, 2000
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventors: Gerd Ascher, Johannes Ludescher, Hubert Sturm, Josef Wieser
  • Patent number: 5856474
    Abstract: Cephalosporin derivatives of formula ##STR1## wherein R.sub.1 signifies hydrogen or a silyl protecting group, processes for their production and their use as intermediate products.
    Type: Grant
    Filed: October 23, 1996
    Date of Patent: January 5, 1999
    Assignee: Biochemie Gesellschaft, m.b.H.
    Inventors: Gerd Ascher, Johannes Ludescher, Hubert Sturm, Josef Wieser
  • Patent number: 5585485
    Abstract: A cephalosporin intermediate of the formula ##STR1## where R.sub.3 is carboxyl, carboxylate, or a carboxylic acid ester group and,R.sub.8 and R.sub.9 are each independently hydrogen, halogen,(C.sub.1-4) alkyl, hydroxy, carboxamido,(C.sub.1-4) alkoxycarbonyl, amino,mono- (C.sub.1-4) alkylamino, di- (C.sub.1-4) alkylamino, ortogether are a 5 or 6-membered carbocyclic ring or an alkali metal, alkaline earth metal, or acid addition salt thereof. Valuable cephalosporin antibiotics can be produced from the cephalosporin intermediate products of formula I.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 17, 1996
    Assignee: Biochemie Gesellschaft m.b.h.
    Inventors: Gerd Ascher, Hubert Sturm, Heinrich Thaler, Werner Veit
  • Patent number: 5401841
    Abstract: The invention relates to a new, economical and simple process for the production of 3-vinylcephalosporin compounds of formula ##STR1## wherein R.sub.1 and R.sub.2 may be the same or different and denote hydrogen or an organic radical.
    Type: Grant
    Filed: May 28, 1993
    Date of Patent: March 28, 1995
    Assignee: Sandoz Ltd.
    Inventors: Gerd Ascher, Johannes Ludescher, Hubert Sturm
  • Patent number: 5138049
    Abstract: The invention relates to a nitrate of (6R,7R)-7-{[2-(2-amino-4-thiazolyl)]-2-oxoacetamido}-3-(1,2,3-thiadizol-5- yl)thiomethyl-3-cephem-4-carboxylic acid, a process for its production and its use.
    Type: Grant
    Filed: January 18, 1991
    Date of Patent: August 11, 1992
    Assignee: Biochemie
    Inventors: Gerd Ascher, Hubert Sturm
  • Patent number: 5003073
    Abstract: Process for the production of known 2-oximinoacetamido-3-cephem-4-carboxylic derivatives comprising acylation of 7-amino-3-cephem-4-carboxylic acid derivatives with novel 2-oximinoacetic acid thio esters, as well as such thioesters and their production.
    Type: Grant
    Filed: July 24, 1989
    Date of Patent: March 26, 1991
    Assignee: Sandoz Ltd.
    Inventor: Gerd Ascher
  • Patent number: 4767852
    Abstract: Process for the production of known 2-oximinoacetamido-3-cephem-4-carboxylic derivatives comprising acylation of 7-amino-3-cephem-4-carboxylic acid derivatives with novel 2-oximinoacetic acid thio esters, as well as such thioesters and their production.
    Type: Grant
    Filed: November 19, 1986
    Date of Patent: August 30, 1988
    Assignee: Biochemie
    Inventor: Gerd Ascher
  • Patent number: 4708825
    Abstract: The invention provides a novel method for producing phenylglycyl chloride hydrochlorides involving reaction of N-substituted phenylglycines with for example thionyl chloride and then gaseous hydrogen chloride, as well as certain novel starting materials for use in this process and certain end-products thereby produced.
    Type: Grant
    Filed: July 8, 1983
    Date of Patent: November 24, 1987
    Assignee: Biochemie
    Inventors: Gerd Ascher, Kurt Riedl
  • Patent number: 4322526
    Abstract: Novel Cephalosporin C derivatives, their production and their use in isolating Cephalosporin C from culture filtrates for subsequent conversion of 7-aminocephalosporanic acid.
    Type: Grant
    Filed: December 29, 1980
    Date of Patent: March 30, 1982
    Assignee: Sandoz Ltd.
    Inventor: Gerd Ascher
  • Patent number: 4267321
    Abstract: Novel Cephalosporin C derivatives, their production and their use in isolating Cephalosporin C from culture filtrates for subsequent conversion to 7-aminocephalosporanic acid.
    Type: Grant
    Filed: January 22, 1980
    Date of Patent: May 12, 1981
    Assignee: Sandoz Ltd.
    Inventor: Gerd Ascher
  • Patent number: 4057557
    Abstract: The invention provides novel 5-nitrothiazolylimidazoline derivatives, useful as chemotherapeutic agents.
    Type: Grant
    Filed: February 6, 1976
    Date of Patent: November 8, 1977
    Assignee: Sandoz Ltd.
    Inventors: Gerd Ascher, Hellmuth Reinshagen
  • Patent number: 4055646
    Abstract: This invention provides novel 5-nitrothiazolo-2-imidazoles which are useful as chemotherapeutical agents.
    Type: Grant
    Filed: February 6, 1976
    Date of Patent: October 25, 1977
    Assignee: Sandoz Ltd.
    Inventors: Gerd Ascher, Hellmuth Reinshagen