Patents by Inventor Gerhard Hempel

Gerhard Hempel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 21-bromo-4-pregnene-3,20-dione derivatives
    Patent number: 5332847
    Abstract: A process is disclosed for the preparation of 21-bromo-4-pregnene-3,20-dione derivatives of general Formula I ##STR1## wherein R.sub.1 is a hydrogen atom, a hydroxy group or an alkanoyl group of up to 6 carbon atoms,R.sub.2 symbolizes a hydrogen atom or a methyl group, or whereinR.sub.1 and R.sub.2 jointly mean an isopropylidenedioxy group,whereinR.sub.3 is a hydrogen atom, a fluorine atom or a methyl group,V is a methylene group or ethylene group,X is a hydrogen atom, a fluorine atom or a chlorine atom, andY is a methylene group, a hydroxymethylene group or a carbonyl group.
    Type: Grant
    Filed: June 15, 1992
    Date of Patent: July 26, 1994
    Assignee: Schering Aktiengesellschaft
    Inventor: Gerhard Hempel, deceased
  • Process for production of 6.alpha.,9.alpha.-difluoro-11.beta.,17.alpha.-dihydroxy-16.alpha.-methyl -4-pregnene-3,20-dione and its derivatives
    Patent number: 4898693
    Abstract: 6.alpha.,9.alpha.-difluoro-11.beta.,17.alpha.-dihydroxy-16.alpha.-methyl-4- pregnene-3,20-dione and its derivatives of general formula I ##STR1## wherein symbolizes a single bond or a double bond, andX is H, Br, I or alkanoyloxy with 1-8 carbon atoms, are prepared by a novel process from 3.beta.,17.alpha.-dihydroxy-16.alpha.-methyl-5-pregnen-20-one. The resultant pregnene derivatives are useful as intermediates in the production of flumethasone.
    Type: Grant
    Filed: November 30, 1987
    Date of Patent: February 6, 1990
    Assignee: Schering Aktiengesellschaft
    Inventors: Gerhard Hempel, Mario Kennecke, Bernhard Krieger, Rainer Phillippson, Hermann Triem, Alfred Weber