Patents by Inventor Gi Hoon NAM

Gi Hoon NAM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR INDUCING RESOLUTIVE MACROPHAGE AND USES THEROF
    Publication number: 20240050523
    Abstract: The present invention generally relates to an extracellular vesicle (EV) comprising a subunit of a heterodimeric transcription factor, an EV polypeptide, and a monomeric cis-cleaving intein and a method of using the EV.
    Type: Application
    Filed: August 9, 2023
    Publication date: February 15, 2024
    Inventors: Gi-Hoon NAM, Gi Beom KIM, Jae Hyun KIM, Yeji LEE, Jiyoung GOO, Seongeun CHO, Cherlhyun JEONG, In-San KIM
  • METHOD FOR TREATING CANCER AND INFLAMMATORY DISEASES USING STEM CELL- DERIVED EXTRACELLULAR VESICLES COMPRISING SIRP
    Publication number: 20240024418
    Abstract: The present invention generally relates to a stem cell-derived extracellular vesicle (EV) comprising a signal regulatory protein (SIRP) and a method for preventing or treating cancer and/or inflammatory disease, condition, or symptom by using the stem cell-derived EV.
    Type: Application
    Filed: July 24, 2023
    Publication date: January 25, 2024
    Inventors: Gi-Hoon NAM, Gi Beom KIM, Seohyun KIM, Yoon Kyoung KIM, Jae Hyun KIM, Seonghyun KIM
  • SURFACE-ENGINEERED EXTRACELLULAR VESICLES AND THERAPEUTIC USES THEREOF
    Publication number: 20230381226
    Abstract: The present invention provides surface-engineered extracelluar vesicles, compositions comprising the surface-engineered extracelluar vesicles, methods for preparing the surface-engineered extracelluar vesicles, and methods for using the surface-engineered extracelluar vesicles or the compositions.
    Type: Application
    Filed: May 24, 2023
    Publication date: November 30, 2023
    Inventors: In San KIM, Seungyoon PARK, Gi-Hoon NAM, Inkyu LEE
  • NOVEL RECOMBINANT EXOSOME AND USE THEREOF
    Publication number: 20230226215
    Abstract: The present invention provides a recombinant exosome comprising a membrane-bound EGF protein on the surface of the recombinant exosome and provides a use of the recombinant exosome.
    Type: Application
    Filed: September 30, 2022
    Publication date: July 20, 2023
    Inventors: In-San KIM, Gi-Hoon NAM, Yeon-Sun HONG, Seong Eon CHO
  • PD-1-DECORATED NANOCAGES AND USES THEREOF
    Publication number: 20220409550
    Abstract: Provided are a programmed cell death protein 1 (PD-1)-decorated nanocage and use thereof. The PD-1-decorated nanocage (PdNC) of the present disclosure may block PD-1 and programmed cell death-ligand (PD-L) signaling and may induce anti-tumor immunity activation at two immune checkpoints of tumor microenvironment (TME) (effector phase) and tumor-draining lymph node (TDLN) (innate phase), thereby increasing the adaptability of PD-1 and PD-L blockade-based therapy. Accordingly, it may be applied to various kinds of cancer therapies.
    Type: Application
    Filed: June 17, 2022
    Publication date: December 29, 2022
    Applicants: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: In-San KIM, Eun Jung LEE, Gi-hoon NAM, Gi-beom KIM, Hyo-Dong SUNG
  • Nanocage and use thereof
    Patent number: 10905774
    Abstract: The present invention relates to a novel recombinant nanocage and use thereof wherein the nanocage is formed by self-assembly of a fusion protein including a phagocytosis enhancing protein and a self-assembling protein, and to a protein nanocage complex in which an immunogenic cell death inducer is loaded in the nanocage as an active ingredient.
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: February 2, 2021
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Gi Hoon Nam, Eun Jung Lee, Yoo Soo Yang, Cherl Hyun Jeong, In-San Kim, Kwangmeyung Kim
  • NOVEL NANOCAGE AND USE THEREOF
    Publication number: 20190216947
    Abstract: The present invention relates to a novel recombinant nanocage and use thereof wherein the nanocage is formed by self-assembly of a fusion protein including a phagocytosis enhancing protein and a self-assembling protein, and to a protein nanocage complex in which an immunogenic cell death inducer is loaded in the nanocage as an active ingredient.
    Type: Application
    Filed: January 15, 2019
    Publication date: July 18, 2019
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Gi Hoon NAM, Eun Jung Lee, Yoo Soo Yang, Cherl Hyun Jeong, In-San Kim, Kwangmeyung Kim