Patents by Inventor Gilbert Besong
Gilbert Besong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240043428Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.Type: ApplicationFiled: December 21, 2022Publication date: February 8, 2024Inventors: Gilbert BESONG, Christopher Thomas BRAIN, Clinton A. BROOKS, Miles Stuart CONGREVE, Claudio DAGOSTIN, Guo HE, Ying HOU, Steven HOWARD, Yue LI, Yipin LU, Paul MORTENSON, Troy SMITH, Moo Je SUNG, Steven WOODHEAD, Wojciech WRONA, Bharat LAGU
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Patent number: 11248234Abstract: The present invention refers to method for producing a transgenic plant with increased herbicide tolerance or resistance as compared to a corresponding non-transformed wild type plant, comprising transforming a plant cell or a plant cell nucleus or a plant tissue with a nucleic acid molecule encoding a mutated HPPD polypeptide, as well as to the nucleic acid, and plants with increased HPPD-inhibiting herbicide tolerance or resistance comprising the nucleic acid of the invention.Type: GrantFiled: February 10, 2016Date of Patent: February 15, 2022Assignee: BASF SEInventors: Stefan Tresch, Maciej Pasternak, Liliana Parra Rapado, Jill M. Paulik, Jens Lerchl, Gilbert Besong, Markus Kordes, Thomas Mietzner, Eva Stauffer
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Publication number: 20210253578Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.Type: ApplicationFiled: September 16, 2020Publication date: August 19, 2021Inventors: Gilbert BESONG, Christopher Thomas BRAIN, Clinton A. BROOKS, Miles Stuart CONGREVE, Claudio DAGOSTIN, Guo HE, Ying HOU, Steven HOWARD, Yue LI, Yipin LU, Paul MORTENSON, Troy SMITH, Moo Je SUNG, Steven WOODHEAD, Wojciech WRONA, Bharat LAGU
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Patent number: 10619138Abstract: The present invention refers to method for producing a transgenic plant with increased herbicide tolerance or resistance as compared to a corresponding non-transformed wild type plant, comprising transforming a plant cell or a plant cell nucleus or a plant tissue with a nucleic acid molecule encoding a HPPD polypeptide, as well as to the nucleic acid, and plants with increased HPPD-inhibiting herbicide tolerance or resistance comprising the nucleic acid of the invention.Type: GrantFiled: August 12, 2014Date of Patent: April 14, 2020Assignee: BASF SEInventors: Stefan Tresch, Johannes Hutzler, Maciej Pasternak, Liliana Parra Rapado, Jens Lerchl, Gilbert Besong, Helmut Kraus, Matthias Witschel, Jill Marie Paulik
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Patent number: 10167297Abstract: The present invention provides a substituted pyridine compound of the formula I or an agriculturally suitable salt or N-oxide thereof, wherein the variables in the formula I are defined as in the description. Substituted pyridine compounds of formula I are useful as herbicides.Type: GrantFiled: October 22, 2015Date of Patent: January 1, 2019Assignee: BASF SEInventors: Gilbert Besong, Matthias Witschel, Thomas Seitz, Liliana Parra Rapado, Richard Evans, Kristin Hanzlik, Gerd Kraemer, Michael Rack
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Patent number: 10023590Abstract: The present invention provides a substituted pyridine compound of the formula I or an agriculturally suitable salt or N-oxide thereof, wherein the variables in the formula I are defined as in the description. Substituted pyridine compounds of formula I are useful as herbicides.Type: GrantFiled: April 7, 2015Date of Patent: July 17, 2018Assignee: BASF SEInventors: Gilbert Besong, Matthias Witschel, Ruediger Reingruber, Helmut Kraus, Thomas Seitz, Liliana Parra Rapado, Trevor William Newton, Gerd Kraemer, Richard Roger Evans, Michael Rack
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Publication number: 20180155351Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.Type: ApplicationFiled: February 1, 2018Publication date: June 7, 2018Inventors: Gilbert Besong, Christopher Thomas Brain, Clinton A. Brooks, Miles Stuart Congreve, Claudio Dagostin, Guo He, Ying Hou, Steven Howard, Yue Li, Yipin Lu, Paul Mortenson, Troy Smith, Moo Je Sung, Steven Woodhead, Wojciech Wrona, Bharat Lagu
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Publication number: 20180023060Abstract: The present invention refers to method for producing a transgenic plant with increased herbicide tolerance or resistance as compared to a corresponding non-transformed wild type plant, comprising transforming a plant cell or a plant cell nucleus or a plant tissue with a nucleic acid molecule encoding a mutated HPPD polypeptide, as well as to the nucleic acid, and plants with increased HPPD-inhibiting herbicide tolerance or resistance comprising the nucleic acid of the invention.Type: ApplicationFiled: February 10, 2016Publication date: January 25, 2018Inventors: Stefan Tresch, Maciej Pasternak, Liliana Parra Rapado, Jill Paulik, Jens Lerchl, Gilbert Besong, Markus Kordes, Thomas Mietzner, Eva Stauffer
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Publication number: 20170349604Abstract: The present invention provides a substituted pyridine compound of the formula I or an agriculturally suitable salt or N-oxide thereof, wherein the variables in the formula I are defined as in the description. Substituted pyridine compounds of formula I are useful as herbicides.Type: ApplicationFiled: October 22, 2015Publication date: December 7, 2017Inventors: Gilbert BESONG, Matthias WITSCHEL, Thomas SEITZ, Liliana PARRA RAPADO, Richard EVANS, Kristin HANZLIK, Gerd KRAEMER, Michael RACK
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Publication number: 20170183352Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.Type: ApplicationFiled: August 8, 2016Publication date: June 29, 2017Applicants: Novartis AG, Astex Therapeutics Ltd.Inventors: Gilbert BESONG, Christopher Thomas BRAIN, Clinton A. BROOKS, Miles Stuart CONGREVE, Claudio DAGOSTIN, Guo HE, Ying HOU, Steven HOWARD, Yue LI, Yipin LU, Paul MORTENSON, Troy SMITH, Moo Je SUNG, Steven WOODHEAD, Wojciech WRONA, Bharat LAGU
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Publication number: 20170121343Abstract: The present invention provides a substituted pyridine compound of the formula I or an agriculturally suitable salt or N-oxide thereof, wherein the variables in the formula I are defined as in the description. Substituted pyridine compounds of formula I are useful as herbicides.Type: ApplicationFiled: April 7, 2015Publication date: May 4, 2017Inventors: Gilbert BESONG, Matthias WITSCHEL, Ruediger REINGRUBER, Helmut KRAUS, Thomas SEITZ, Liliana PARRA RAPADO, Trevor William NEWTON, Gerd KRAEMER, Richard Roger EVANS, Michael RACK
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Publication number: 20160376567Abstract: The present invention refers to method for producing a transgenic plant with increased herbicide tolerance or resistance as compared to a corresponding non-transformed wild type plant, comprising transforming a plant cell or a plant cell nucleus or a plant tissue with a nucleic acid molecule encoding a HPPD polypeptide, as well as to the nucleic acid, and plants with increased HPPD-inhibiting herbicide tolerance or resistance comprising the nucleic acid of the invention.Type: ApplicationFiled: August 12, 2014Publication date: December 29, 2016Applicant: BASF SEInventors: Stefan Tresch, Johannes Hutzler, Maciej Pasternak, Liliana Parra Rapado, Jens Lerchl, Gilbert Besong, Helmut Kraus, Matthias Witschel, Jill Marie Paulik
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Patent number: 9416136Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.Type: GrantFiled: January 17, 2014Date of Patent: August 16, 2016Assignees: Novartis AG, Astex Therapeutics, Ltd.Inventors: Gilbert Besong, Christopher Thomas Brain, Clinton A Brooks, Miles Stuart Congreve, Claudio Dagostin, Guo He, Ying Hou, Steven Howard, Yue Li, Yipin Lu, Paul Mortenson, Troy Smith, Moo Je Sung, Steven Woodhead, Wojciech Wrona, Bharat Lagu
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Publication number: 20160102103Abstract: The present invention provides a substituted pyridine compound of the formula I or an agriculturally suitable salt or N-oxide thereof, wherein the variables in the formula I are defined as in the description. Substituted pyridine compounds of formula I are useful as herbicides.Type: ApplicationFiled: May 14, 2014Publication date: April 14, 2016Inventors: Gilbert BESONG, Matthias WITSCHEL, Ruediger REINGRUBER, Helmut KRAUS, Thomas SEITZ, Liliana PARRA-RAPADO, Trevor William NEWTON, Gerd KRAEMER, Richard Roger EVANS, Michael RACK
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Publication number: 20150181879Abstract: The present invention provides a substituted pyridine compound of the formula I or an agriculturally suitable salt or N-oxide thereof, wherein the variables in the formula I are defined as in the description. Substituted pyridine compounds of formula I are useful as herbicides.Type: ApplicationFiled: May 27, 2013Publication date: July 2, 2015Inventors: Matthias Witschel, Helmut Kraus, Johannes Hutzler, Trevor William Newton, Ruediger Reingruber, Timo Frassetto, Liliana Parra Rapado, Gilbert Besong, Michael Rack, Andree van der Kloet, Thomas Seitz, Jens Lerchl, Klaus Kreuz, Maciej Pasternak, Richard Roger Evans
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Patent number: 8877683Abstract: The present invention provides substituted pyridine compounds of the formula I or N-oxides or agriculturally suitable salts thereof, wherein the variables in the formula I are defined as in the description. Substituted pyridines of formula I are useful as herbicides.Type: GrantFiled: December 19, 2011Date of Patent: November 4, 2014Assignee: BASF SEInventors: Matthias Witschel, William Karl Moberg, Liliana Parra Rapado, Gilbert Besong, Michael Rack, Andree Van Der Kloet, Thomas Seitz, Ruediger Reingruber, Helmut Kraus, Johannes Hutzler, Trevor William Newton, Jens Lerchl, Klaus Kreuz, Klaus Grossmann, Richard Roger Evans
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Publication number: 20140135312Abstract: The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases. Furthermore, there is a need for methods for modulating the activity of protein kinases, such as CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8 and CDK9, using the compounds provided herein.Type: ApplicationFiled: January 17, 2014Publication date: May 15, 2014Applicants: Astex Therapeutics Ltd., Novartis AGInventors: Gilbert BESONG, Christopher Thomas Brain, Clinton A. Brooks, Miles Stuart Congreve, Claudio Dagostin, Guo He, Ying Huo, Steven Howard, Yue Ll, Yipin Lu, Paul Mortenston, Troy Smith, Moo Je Sung, Steven Woodhead, Wojciech Wrona, Bharat Lagu
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Publication number: 20140094368Abstract: The present invention provides substituted pyridine compounds of the formula I or N-oxides or agriculturally suitable salts thereof, wherein the variables in the formula I are defined as in the description. Substituted pyridines of formula I are useful as herbicides.Type: ApplicationFiled: June 8, 2012Publication date: April 3, 2014Applicant: BASF SEInventors: Matthias Witschel, Helmut Kraus, Johannes Hutzler, Trevor William Newton, Jens Lerchl, Klaus Kreuz, Klaus Grossmann, Richard Roger Evans, Ruediger Reingruber, Liliana Parra Rapado, Gilbert Besong, Michael Rack, Andree Van Der Kloet, Thomas Seitz
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Publication number: 20130288899Abstract: The present invention provides substituted pyridine compounds of the formula I or N-oxides or agriculturally suitable salts thereof, wherein the variables in the formula I are defined as in the description. Substituted pyridines of formula I are useful as herbicides.Type: ApplicationFiled: December 19, 2011Publication date: October 31, 2013Applicant: BASF SEInventors: Matthias Witschel, William Karl Moberg, Liliana Parra Rapado, Gilbert Besong, Michael Rack, Andree Van Der Kloet, Thomas Seitz, Ruediger Reingruber, Helmut Kraus, Johannes Hutzler, Trevor William Newton, Jens Lerchl, Klaus Kreuz, Klaus Grossmann, Richard Roger Evans
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Publication number: 20130274109Abstract: The present invention provides substituted pyrazine compounds of the formula I or N-oxides or agriculturally suitable salts thereof, wherein the variables in the formula I are defined as in the description. Substituted pyrazines of formula I are useful as herbicides.Type: ApplicationFiled: December 23, 2011Publication date: October 17, 2013Applicant: BASF SEInventors: Ruediger Reingruber, Helmut Kraus, Johannes Hutzler, Trevor William Newton, Matthias Witschel, William Karl Moberg, Liliana Parra Rapado, Gilbert Besong, Michael Rack, Andree Van Der Kloet, Thomas Seitz, Jens Lerchl, Klaus Kreuz, Klaus Grossmann, Richard Roger Evans
