Patents by Inventor Gilbert Marie

Gilbert Marie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10829478
    Abstract: The present invention discloses compounds according to Formula I: Wherein R1, R2, R3a, R3b, R6a, R6b, the subscript n and Cy are as defined herein. The present invention relates to compounds inhibiting ADAMTS, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis by administering the compound of the invention.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: November 10, 2020
    Assignee: GALAPAGOS NV
    Inventors: Frédéric Gilbert Labéguère, Rama Heng, Frédéric André De Ceuninck, Luke Jonathan Alvey, David Amantini, Franck Laurent Brebion, Pierre Marc Marie Joseph Deprez, Romain Luc Marie Gosmini, Hélène Marie Jary, Christophe Peixoto, Iuliana Ecaterina Pop-Botez, Marie Laurence Claire Varin
  • Patent number: 10619138
    Abstract: The present invention refers to method for producing a transgenic plant with increased herbicide tolerance or resistance as compared to a corresponding non-transformed wild type plant, comprising transforming a plant cell or a plant cell nucleus or a plant tissue with a nucleic acid molecule encoding a HPPD polypeptide, as well as to the nucleic acid, and plants with increased HPPD-inhibiting herbicide tolerance or resistance comprising the nucleic acid of the invention.
    Type: Grant
    Filed: August 12, 2014
    Date of Patent: April 14, 2020
    Assignee: BASF SE
    Inventors: Stefan Tresch, Johannes Hutzler, Maciej Pasternak, Liliana Parra Rapado, Jens Lerchl, Gilbert Besong, Helmut Kraus, Matthias Witschel, Jill Marie Paulik
  • Patent number: 10550100
    Abstract: The present invention discloses compounds according to Formula I: Wherein R1, R2, R3a, R3b, R6, Cy, and the subscript n are as defined herein. The present invention relates to compounds inhibiting ADAMTS, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis by administering the compound of the invention.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: February 4, 2020
    Assignee: GALAPAGOS NV
    Inventors: Frédéric Gilbert Labéguère, Rama Heng, Frédéric André De Ceuninck, Luke Jonathan Alvey, David Amantini, Franck Laurent Brebion, Pierre Marc Marie Joseph Deprez, Romain Luc Marie Gosmini, Hélène Marie Jary, Christophe Peixoto, Iuliana Ecaterina Pop-Botez, Marie Laurence Claire Varin
  • Publication number: 20190315719
    Abstract: The present invention discloses compounds according to Formula I: Wherein R1, R2, R3a, R3b, R6a, R6b, the subscript n and Cy are as defined herein. The present invention relates to compounds inhibiting ADAMTS, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis by administering the compound of the invention.
    Type: Application
    Filed: June 1, 2017
    Publication date: October 17, 2019
    Inventors: Frédéric Gilbert LABÉGUÈRE, Rama HENG, Frédéric André DE CEUNINCK, Luke Jonathan ALVEY, David AMANTINI, Franck Laurent BREBION, Pierre Marc Marie Joseph DEPREZ, Romain Luc Marie GOSMINI, Hélène Marie JARY, Christophe PEIXOTO, Iuliana Ecaterina POP-BOTEZ, Marie Laurence Claire VARIN
  • Publication number: 20190300503
    Abstract: The present invention discloses compounds according to Formula I: Wherein R1, R2, R3a, R3b, R6, Cy, and the subscript n are as defined herein. The present invention relates to compounds inhibiting ADAMTS, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis by administering the compound of the invention.
    Type: Application
    Filed: June 1, 2017
    Publication date: October 3, 2019
    Inventors: Frédéric Gilbert LABÉGUÈRE, Rama HENG, Frédéric André DE CEUNINCK, Luke Jonathan ALVEY, David AMANTINI, Franck Laurent BREBION, Pierre Marc Marie Joseph DEPREZ, Romain Luc Marie GOSMINI, Hélène Marie JARY, Christophe PEIXOTO, Iuliana Ecaterina POP-BOTEZ, Marie Laurence Claire VARIN
  • Patent number: 5055213
    Abstract: The invention relates to additives to lubricants resulting from the condensation of a primary or secondary amine and/or of an alkylene polyamine with a copolymer containing vicinal carboxylic groups.Derivatives of phenothiazine, or naphthylamine and of diphenylamine are employed in most cases as alkylene polyamine.These compounds can be employed as multifunctional additives to lubricants.
    Type: Grant
    Filed: December 7, 1989
    Date of Patent: October 8, 1991
    Assignee: Societe Nationale Elf Aquitaine
    Inventors: Laurent Germanaud, Nguyen Truong-Dinh, Gilbert Marie, Patrick Turello
  • Patent number: 4986924
    Abstract: The invention provides polymeric compounds resulting from the condensation of a primary amine having one phenolic group in its molecule with a copolymer of carboxylic acid functions.The copolymer is formed by copolymerization of an unsaturated monocarboxylic acid with at least one derivative of such a acid or by grafting of an unsaturated acid on a hydrocarbon polymer. These compounds can be especially used as multifunctional additives to lubricants.
    Type: Grant
    Filed: November 3, 1988
    Date of Patent: January 22, 1991
    Assignee: Societe Nationale Elf Aquitaine
    Inventors: Laurent Germanaud, Nguyen Truong Dinh, Gilbert Marie, Patrick Turello
  • Patent number: 4259208
    Abstract: A process for making crystalline polymers or copolymers of alpha-olefins containing 3 to 8 carbon atoms, such as polypropylene, by polymerization with a catalyst consisting of a combination of titanium chloride and an organic aluminium compound, in the presence of a stereospecificity additive.This stereospecificity additive has the formula:R.sub.1 --O--(C.sub.p H.sub.2p)--S--R.sub.2,where:R.sub.1 and R.sub.2 are alkyl radicals containing 1 to 4 carbon atoms or are linked together to form a divalent --(C.sub.m H.sub.2m)--radical, andp and m are integers each with a value of 1 to 6;this additive may be used in the presence of an activator.
    Type: Grant
    Filed: March 26, 1980
    Date of Patent: March 31, 1981
    Assignee: ATO Chemie
    Inventor: Gilbert Marie
  • Patent number: 4256874
    Abstract: Isotactic and atactic polypropylene of acceptable purity are obtained by contacting the polymerized polymer with a mixture of hydrocarbon, alcohol, organic acid and diketone.
    Type: Grant
    Filed: January 26, 1979
    Date of Patent: March 17, 1981
    Assignee: Ato Chimie
    Inventor: Gilbert Marie
  • Patent number: 4228252
    Abstract: A process for making crystalline polymers or copolymers of alpha-olefins containing 3 to 8 carbon atoms, such as polypropylene, by polymerization with a catalyst consisting of a combination of titanium chloride and an organic aluminum compound, in the presence of a stereospecificity additive.This stereospecificity additive has the formula:R.sub.1 --O--(C.sub.p H.sub.2p)--S--R.sub.2,where:R.sub.1 and R.sub.2 are alkyl radicals containing 1 to 4 carbon atoms or are linked together to form a divalent --(C.sub.m H.sub.2m)--radical, andp and m are integers each with a value of 1 to 6;this additive may be used in the presence of an activator.
    Type: Grant
    Filed: June 13, 1979
    Date of Patent: October 14, 1980
    Assignee: Ato Chimie
    Inventor: Gilbert Marie
  • Patent number: 4228253
    Abstract: A process for making crystalline polymers or copolymers of alpha-olefins containing 3 to 8 carbon atoms, such as polypropylene, by polymerization with a catalyst consisting of a combination of titanium chloride and an organic aluminum compound, in the presence of a stereospecificity additive.This stereospecificity additive is a cyclic polyether of the crown ether type, which may contain sulphur atoms and/or nitro radicals; this additive may be used together with an activator.The process produces polymers or copolymers with a high isotacticity index, while keeping catalyst activity sufficiently high.
    Type: Grant
    Filed: June 13, 1979
    Date of Patent: October 14, 1980
    Assignee: Ato Chimie
    Inventor: Gilbert Marie
  • Patent number: 4170561
    Abstract: There are disclosed novel lubricating compositions containing a major proportion of a lubricating oil and a minor proportion of an oil soluble polymer additive, and possibly other additives, wherein said polymer additive is a copolymer of ethylene, a monoolefin having 3 to 6 carbon atoms or a monoolefin having 3 to 6 carbon atoms and a non-conjugated diene with one or more specific nitrogenous monomers, said polymer having a reduced viscosity, measured in decalin at 135.degree. C., comprised between 0.5 and 2 and a polydispersity lower than 5.Such a polymer additive improves the oil viscosity index while ensuring the dispersion of the slurry it may contain.
    Type: Grant
    Filed: March 15, 1978
    Date of Patent: October 9, 1979
    Assignee: Entreprise de Recherches et d'Activities Petrolieres (E.R.A.P.)
    Inventors: Gilbert Chapelet, Hubert Knoche, Gilbert Marie
  • Patent number: 4148845
    Abstract: Novel amorphous copolymers of mono-olefins or of mono-olefins and non-conjugated dienes with unsaturated derivatives of imides are disclosed. These copolymers containing from 99.9 to 80% by weight of non-polar units derived from at least two mono-olefins containing 2 to 18 carbon atoms, particularly ethylene and propene or ethylene and butene-1, and possibly one or more non-conjugated dienes, and from 0.1 to 20% units derived from an imide having the formula: ##STR1## wherein: Z is an alkenyl radical containing 2 to 16 carbon atoms, and A designates a saturated or unsaturated divalent hydrocarbon radical which contains 2 to 12 carbon atoms and which may possibly carry amino, halogen or carboxyl groups. Also disclosed are graft amorphous copolymers of amorphous copolymers of olefins or of olefins and non-conjugated dienes substrates with unsaturated derivatives of cyclic imides grafted thereon.
    Type: Grant
    Filed: September 28, 1977
    Date of Patent: April 10, 1979
    Assignee: Societe Nationale Elf Aquitaine
    Inventors: Gilbert Marie, Andre Lang, Gilbert Chapelet
  • Patent number: 4139417
    Abstract: Novel amorphous copolymers of mono-olefins or of mono-olefins and non-conjugated dienes with unsaturated derivatives of imides, are disclosed. These copolymers containing from 99.9 to 80% by weight of non-polar units derived from at least two mono-olefins containing 2 to 18 carbon atoms, particularly ethylene and propene or ethylene and butene-1, and possibly one or more non-conjugated dienes, and from 0.1 to 20% units derived from an amide having the formula: ##STR1## wherein: Z is an alkenyl radical containing 2 to 16 carbon atoms, andA designates a saturated or unsaturated divalent hydrocarbon radical which contains 2 to 12 carbon atoms and which may possibly carry amino, halogeno or carboxyl groups.Some of said copolymers may be used as polymer additives in lubricating compounds to improve their viscosity index and to disperse the slurry which they may contain.
    Type: Grant
    Filed: November 16, 1977
    Date of Patent: February 13, 1979
    Assignee: Societe Nationale Elf Aquitaine
    Inventors: Gilbert Marie, Andre Lang, Gilbert Chapelet
  • Patent number: 4092255
    Abstract: There are disclosed novel lubricating compositions containing a major proportion of a lubricating oil and a minor proportion of an oil soluble polymer additive, and possibly other additives, wherein said polymer additive is a copolymer of ethylene, a monoolefin having 3 to 6 carbon atoms or a monoolefin having 3 to 6 carbon atoms and a non-conjugated diene with one or more specific nitrogenous monomers, said polymer having a reduced viscosity, measured in decalin at 135.degree. C, comprised between 0.5 and 2 and a polydispersity lower than 5.Such a polymer additive improves the oil viscosity index while ensuring the dispersion of the slurry it may contain.
    Type: Grant
    Filed: December 8, 1975
    Date of Patent: May 30, 1978
    Assignee: Entreprise de Recherches et d'Activites Petrolieres (E.R.A.P.)
    Inventors: Gilbert Chapelet, Hubert Knoche, Gilbert Marie
  • Patent number: 4063010
    Abstract: Novel amorphous copolymers of mono-olefins or of mono-olefins and non-conjugated dienes with unsaturated derivatives of imides are disclosed. These copolymers containing from 99.9 to 80% by weight of non-polar units derived from at least two mono-olefins containing 2 to 18 carbon atoms, particularly ethylene and propene or ethylene and butene-1, and possibly one or more non-conjugated dienes, and from 0.1 to 20% units derived from an imide having the formula ##STR1## wherein Z is an alkenyl radical containing 2 to 16 carbon atoms, andA designates a saturated or unsaturated divalent hydrocarbon radical which contains 2 to 12 carbon atoms and which may possibly carry amino, halogeno or carboxyl groups.Some of said copolymers may be used as polymer additives in lubricating compounds to improve their viscosity index and to disperse the slurry which they may contain.
    Type: Grant
    Filed: December 3, 1975
    Date of Patent: December 13, 1977
    Assignee: Societe Nationale Elf Aquitaine (SNEA)
    Inventors: Gilbert Marie, Andre Lang, Gilbert Chapelet
  • Patent number: 3968354
    Abstract: A transversal digital filter including a shift register provided with a number of stages to which level control devices are connected by means of taps, the level control devices being connected to a feedback circuit which is connected through a combination device to the input of the shift register, a delta modulator being incorporated between the combination device and the input of the shift register, and a feedback circuit associated with the delta modulator forming part of the filter.
    Type: Grant
    Filed: July 17, 1974
    Date of Patent: July 6, 1976
    Assignee: T.R.T. Telecommunications Radioelectriques
    Inventor: Gilbert Marie Marcel Ferrieu
  • Patent number: D884693
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: May 19, 2020
    Assignee: AKSOR
    Inventor: Jacques Gilbert Marie Mangeot
  • Patent number: D884694
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: May 19, 2020
    Assignee: AKSOR
    Inventor: Jacques Gilbert Marie Mangeot
  • Patent number: D886096
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: June 2, 2020
    Assignee: AKSOR
    Inventor: Jacques Gilbert Marie Mangeot