Abstract: A delivery cartridge, delivery system and a method for delivering a medical device are provided. The delivery cartridge includes a housing having a proximal end, a distal end and a cavity defined therein. The delivery cartridge further includes a proximal end covering member connected to the proximal end, a distal end covering member connected to the distal end, and a medical device positioned within the cavity. The housing is adapted to fit within a lumen of a delivery system.

Abstract: Implantable prosthetic valves comprising support frames are provided. The support frames may include a plurality of symmetrically arrayed interconnected U-shaped member structures. Preferred support frames are tubular structures enclosing a longitudinal axis and including a plurality of U-shaped member structures facing a distal or a proximal end of the support frame. Each U-shaped member structure may be connected to a single longitudinally adjacent U-shaped member facing in an opposite longitudinal direction, as well as two laterally adjacent U-shaped members.

Abstract: The disclosure relates to support frames for prosthetic implantable valves. The support frames may include a plurality of symmetrically arrayed interconnected U-shaped member structures. Preferred support frames are tubular structures enclosing a longitudinal axis and including a plurality of U-shaped member structures facing a distal or a proximal end of the support frame. Each U-shaped member structure may be connected to a single longitudinally adjacent U-shaped member facing in an opposite longitudinal direction, as well as two laterally adjacent U-shaped members.

Abstract: The disclosure relates to implantable prosthetic valves comprising support frames. The support frames may include a plurality of symmetrically arrayed interconnected U-shaped member structures. Preferred support frames are tubular structures enclosing a longitudinal axis and including a plurality of U-shaped member structures facing a distal or a proximal end of the support frame. Each U-shaped member structure may be connected to a single longitudinally adjacent U-shaped member facing in an opposite longitudinal direction, as well as two laterally adjacent U-shaped members.

Abstract: A delivery system for implanting a medical device into the body of a patient or subject and a method of use thereof. The delivery system includes a delivery catheter having a catheter lumen and an inner member extending therethrough. The inner member includes a distal tip portion, a proximal portion, and an intermediate portion, the intermediate portion being disposed adjacent to the distal end of the delivery catheter. A first sealing member, positioned near a distal end of the proximal portion, forms a fluid seal between the inner member and an inside surface of the delivery catheter. A second sealing member, positioned near a proximal end of the distal tip portion, forms a fluid seal between the inner member and an inside surface of the delivery catheter. The intermediate portion extends between the first seal and the second seal. In one embodiment, a medical device and a hydrating fluid are present in a device-containing region between the intermediate portion and the delivery catheter.

Abstract: The invention relates to minimally invasive device for delivering therapeutic or diagnostic agents into a vessel wall. The device includes an introducer tube, a tubular member having a proximal end, a distal end, and a first lumen extending therebetween, the tubular member being slidably disposed within the introducer tube; a plurality of hollow delivery struts, each delivery strut adapted to pierce through inner most layers of the vessel wall and each comprising at least one exit port and at least one stopper to prevent the delivery strut from piercing through the outer most layers of the vessel wall. The delivery struts are disposed on the distal end of the tubular member and are in fluid communication with the first lumen. The invention also relates to methods of delivering the device of this invention and methods of treating conditions or diseases of body lumens.

Abstract: An adjustable length catheter device, a kit and a method of providing the adjustable length catheter device to a patient are provided. The catheter device includes an elongate shaft having a proximal portion, a distal portion, a first lumen and a second lumen extending at least partially therethrough. The catheter device further includes a manifold operably connected to the shaft. The manifold is configured to longitudinally move along the shaft towards the distal portion for separating the proximal portion of the shaft into a first proximal shaft portion including the first lumen and a second proximal shaft portion including the second lumen.

Abstract: Medical device delivery systems and associated methods are provided. Delivery systems according to the invention include an elongated tubular member and a body member, such as a dilator, disposed therein. An intraluminal medical device is disposed on the dilator and within the tubular member prior to deployment. The delivery system includes a means for separating two or more portions of the distal end of the tubular member that aids in deploying the intraluminal medical device from the delivery system by separating two or more portions of the tubular member from each other to facilitate release of the intraluminal medical device from the body member. Various structures can be used for means for separating, including a cutting ring, activateable material on the tubular member, or other suitable structure. The provided devices and methods reduce friction occuring from relative movement between the sheath and dilator during deployment.

Abstract: An embolic protection device for capturing emboli in a body vessel having a frame and a z-stent waist band. The frame includes a plurality of struts configured to open radially to define an expanded state of the device for capturing emboli and to fold along the longitudinal axis to define a collapsed state of the device for deployment and retrieval. The waist band has an open and a closed state and is attached to within the frame between a proximal and distal end. The waist band is formed of a plurality of members attached at a joint to an adjacent member such that the members lie substantially parallel in the closed state and form a “Z” pattern in the open state. A filter portion is attached to the waist band and configured to capture emboli in the expanded state.

Abstract: Anastomoses devices including a stent structure or structures are provided. In addition, a method of using an anastomosis device to perform anastomoses quickly and efficiently is provided. One advantage of the devices and methods is that they may provide for quick and effective attachment to a vessel. A further advantage is that the second end portion of the anastomosis device may provide for anastomosis without causing trauma to vessel walls and other harmful consequences.

Abstract: The invention is directed to lesion site marking devices and methods. Specifically, the device of this invention typically is made up of a filler body comprising a bioremodelable material comprising an extracellular matrix (ECM) material, such as small intestine submucosa (SIS) and a detectable marker associated with the filler body and adapted to mark a center of the filler body. The device of this invention may also be made up of a filler body comprising a biocompatible polymer, such as THORALON, and a detectable marker associated with the filler body and adapted to mark a center of the filler body.