Patents by Inventor Gregory S. Hamilton

Gregory S. Hamilton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Certain compounds, compositions and methods
    Patent number: 9567363
    Abstract: The present invention provides certain tetrahydrouridine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of making and using such compounds.
    Type: Grant
    Filed: December 29, 2014
    Date of Patent: February 14, 2017
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Gregory S. Hamilton, Takashi Tsukamoto, Dana V. Ferraris, Bridget Duvall, Rena Lapidus
  • CERTAIN COMPOUNDS, COMPOSITIONS AND METHODS
    Publication number: 20150210730
    Abstract: The present invention provides certain tetrahydrouridine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of making and using such compounds.
    Type: Application
    Filed: December 29, 2014
    Publication date: July 30, 2015
    Inventors: Gregory S. Hamilton, Takashi Tsukamoto, Dana V. Ferraris, Bridget Duvall, Rena Lapidus
  • Certain compounds, compositions and methods
    Patent number: 8951987
    Abstract: The present invention provides certain tetrahydrouridine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of making and using such compounds.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: February 10, 2015
    Assignee: Otsuka Pharmaceuticals Co., Ltd.
    Inventors: Gregory S. Hamilton, Takashi Tsukamoto, Dana V. Ferraris, Bridget Duvall, Rena Lapidus
  • Certain Compounds, Compositions and Methods
    Publication number: 20140186335
    Abstract: The present invention provides certain tetrahydrouridine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of making and using such compounds.
    Type: Application
    Filed: November 25, 2013
    Publication date: July 3, 2014
    Applicant: Eisai Inc.
    Inventors: Gregory S. Hamilton, Takashi Tsukamoto, Dana V. Ferraris, Bridget Duvall, Rena Lapidus
  • Certain compounds, compositions and methods
    Patent number: 8618075
    Abstract: The present invention provides certain tetrahydrouridine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of making and using such compounds.
    Type: Grant
    Filed: July 24, 2012
    Date of Patent: December 31, 2013
    Assignee: Eisai Inc.
    Inventors: Gregory S. Hamilton, Takashi Tsukamoto, Dana V. Ferraris, Bridget Duvall, Rena Lapidus
  • Certain Compounds, Compositions and Methods
    Publication number: 20120289475
    Abstract: The present invention provides certain tetrahydrouridine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of making and using such compounds.
    Type: Application
    Filed: July 24, 2012
    Publication date: November 15, 2012
    Inventors: Gregory S. Hamilton, Takashi Tsukamoto, Dana V. Ferraris, Bridget Duvall, Rena Lapidus
  • Certain compounds, compositions and methods
    Patent number: 8268800
    Abstract: The present invention provides certain tetrahydrouridine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of making and using such compounds.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: September 18, 2012
    Assignee: Eisai Inc.
    Inventors: Gregory S. Hamilton, Takashi Tsukamoto, Dana V. Ferraris, Bridget Duvall, Rena Lapidus
  • SMALL MOLECULE INHIBITORS OF ROTAMASE ENZYME ACTIVITY
    Publication number: 20110218343
    Abstract: This invention relates to neurotrophic compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.
    Type: Application
    Filed: May 19, 2011
    Publication date: September 8, 2011
    Applicant: GLIAMED, INC.
    Inventors: Gregory S. Hamilton, Joseph Steiner
  • Small molecule inhibitors of rotamase enzyme activity
    Patent number: 7960570
    Abstract: This invention relates to neurotrophic compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.
    Type: Grant
    Filed: December 8, 2009
    Date of Patent: June 14, 2011
    Assignee: GliaMed, Inc.
    Inventors: Gregory S. Hamilton, Joseph Steiner
  • SMALL MOLECULE INHIBITORS OF ROTAMASE ENZYME ACTIVITY
    Publication number: 20100145071
    Abstract: This invention relates to neurotrophic compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.
    Type: Application
    Filed: December 8, 2009
    Publication date: June 10, 2010
    Applicant: GLIAMED, INC.
    Inventors: Gregory S. Hamilton, Joseph Steiner
  • Small molecule rotamase enzyme inhibitors
    Patent number: 7652060
    Abstract: This invention relates to neurotrophic compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.
    Type: Grant
    Filed: October 12, 2007
    Date of Patent: January 26, 2010
    Assignee: Glia Med, Inc
    Inventors: Gregory S. Hamilton, Joseph P. Steiner
  • Certain Compounds, Compositions and Methods
    Publication number: 20090137521
    Abstract: The present invention provides certain tetrahydrouridine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of making and using such compounds.
    Type: Application
    Filed: October 16, 2008
    Publication date: May 28, 2009
    Inventors: Gregory S. Hamilton, Takashi Tsukamoto, Dana V. Ferraris, Bridget Duvall, Rena Lapidus
  • N-linked sulfonamides of N-heterocyclic carboxylic acids or carboxylic acid isosteres
    Patent number: 7459473
    Abstract: This invention relates to novel N-linked sulfonamides of N-heterocyclic carboxylic acid and carboxylic acid isosteres, their preparation, and use for treating neurological disorders including physically damaged nerves and neurodegenerative diseases, and for treating alopecia and promoting hair growth.
    Type: Grant
    Filed: December 3, 1998
    Date of Patent: December 2, 2008
    Assignee: Glia Med, Inc.
    Inventors: Gregory S. Hamilton, Mark H. Norman, Yong-Qian Wu
  • N-linked sulfonamide of heterocyclic thioesters for vision and memory disorders
    Patent number: 7410995
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using N-linked sulfonamides of heterocyclic thioesters.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: August 12, 2008
    Assignee: GPI Nil Holdings Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • Heterocyclic esters or amides for vision and memory disorders
    Patent number: 7338976
    Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using heterocyclic esters and amides.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: March 4, 2008
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Douglas T. Ross, Gregory S. Hamilton, Joseph P. Steiner
  • Small molecule inhibitors of rotamase enzyme activity
    Patent number: 7282510
    Abstract: This invention relates to neurotrophic N-glyoxyl-prolyl ester compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.
    Type: Grant
    Filed: June 27, 2005
    Date of Patent: October 16, 2007
    Assignee: GliaMed, Inc.
    Inventors: Gregory S. Hamilton, Joseph P. Steiner
  • Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders
    Patent number: 7265150
    Abstract: This invention relates to novel compositions and uses of N-heterocyclic carboxylic acids and carboxylic acid isosteres for treating a vision disorder, improving vision, treating memory impairment or enhancing memory performance in an animal.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: September 4, 2007
    Assignee: GPI NIL Holdings Inc.
    Inventors: Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
  • Aza compounds, pharmaceutical compositions and methods of use
    Patent number: 7253169
    Abstract: The present invention relates to N-substituted cyclic aza compounds, pharmaceutical compositions comprising such compounds, and methods of their use for effecting neuronal activities.
    Type: Grant
    Filed: April 17, 2001
    Date of Patent: August 7, 2007
    Assignee: Gliamed, Inc.
    Inventors: Yong-Qian Wu, Wei Huang, Gregory S. Hamilton
  • Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds
    Patent number: 7153883
    Abstract: This invention relates to novel N-heterocyclic carboxylic acids and carboxylic acid isosteres, their preparation and use for treating neurological disorders including physically damaged nerves and neurodegenerative diseases, for treating alopecia and promoting hair growth, for treating vision disorders and/or improving vision, and for treating memory impairment and/or enhancing memory performance by administering such compounds.
    Type: Grant
    Filed: August 2, 2001
    Date of Patent: December 26, 2006
    Assignee: GPI NIL Holdings Inc.
    Inventors: Gregory S. Hamilton, Mark H. Norman, Yong-Qian Wu
  • Compounds having simultaneous ability to block L-type calcium channels and to inhibit phosphodiesterase type 3 activity
    Patent number: 7098211
    Abstract: The present invention provides compounds that possess inhibitory activity against PDE-3 and L-type calcium channels. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating cardiovascular disease, stroke, epilepsy, ophthalmic disorder or migraine.
    Type: Grant
    Filed: October 7, 2003
    Date of Patent: August 29, 2006
    Assignee: Artesian Therapeutics, Inc.
    Inventors: Gregory S. Hamilton, Harry Jefferson Leighton