Patents by Inventor Guanghui Tian
Guanghui Tian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240119883Abstract: A pixel driving circuit and a display panel are provided. The pixel driving circuit includes a data writing module, a data conversion module, and a current driving module. The data writing module is electrically connected to a first node and configured to transmit a data signal to the first node. The data conversion module is electrically connected to the first node, a second node, and a modulation signal source, and configured to generate a current driving control signal, and to output the current driving control signal to the second node. The current driving module is electrically connected to the second node, a light-emitting control wire, and a light-emitting device, and configured to control the light-emitting device to emit light. An effective pulse of the current driving control signal has different pulse widths in different gray-scale states.Type: ApplicationFiled: October 30, 2022Publication date: April 11, 2024Applicant: WUHAN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD.Inventors: Haiming CAO, Chao TIAN, Fei AI, Guanghui LIU
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Patent number: 11948698Abstract: An experimental system a method for studying jet impact characteristics at a core outlet of a fast reactor are provided. The system includes a jet impact main loop including a water storage tank, plunger pumps, a filter, preheaters, a jet impact chamber, a heat regenerator, a condenser, valves, flow meters and pipelines connecting these facilities; a cooling loop including cooling tower, a cooling pump, a regulating valve and a flow meter; and a makeup water loop including a deionized water machine, a makeup water tank and a plunger pump. Water in the water storage tank flows to the heat regenerator via the plunger pump, is preliminarily heated by the heat regenerator and then is divided into three branches to flow to the jet impact container.Type: GrantFiled: December 28, 2021Date of Patent: April 2, 2024Assignee: Xi'an Jiaotong UniversityInventors: Mingjun Wang, Yingjie Wang, Wenxi Tian, Guanghui Su, Suizheng Qiu
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Publication number: 20230312584Abstract: A salt of nucleoside analog, and crystal form, pharmaceutical composition and use thereof. The salt of nucleoside analog has a structure shown in formula I, wherein X is hydrogen or deuterium; Y is an acid, n is 0.5 to 2, or n is 1. When X is hydrogen or deuterium, Y is hydrogen bromide, and n is 1, the salt of the nucleoside analog exists in the form of a crystal with crystal form I or crystal form A or exists in an amorphous form.Type: ApplicationFiled: October 21, 2021Publication date: October 5, 2023Applicants: VIGONVITA LIFE SCIENCES CO., LTD., SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, WUHAN INSTITUTE OF VIROLOGY, CHINESE ACADEMY OF SCIENCESInventors: Jingshan SHEN, Yuanchao XIE, Leike ZHANG, Gengfu XIAO, Zhen WANG, Hualiang JIANG, Huaqiang XU, Tianwen HU, Guanghui TIAN
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Patent number: 11434226Abstract: The present disclosure relates to a salt of phenyl pyrimidinone compound, a polymorph thereof and a pharmaceutical composition comprising the same and a use thereof, particularly relates to the hydrochlorate of phenyl pyrimidinone compound of following formula (I-A) and a pharmaceutically acceptable polymorph, solvate, hydrate, co-crystal, anhydrous substance, or amorphous form thereof, a pharmaceutical composition and a pharmaceutical unit dosage comprising the same, the preparing method and use thereof.Type: GrantFiled: January 7, 2020Date of Patent: September 6, 2022Assignees: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, SUZHOU VIGONVITA LIFE SCIENCES CO., LTD., TOPHARMAN SHANGHAI CO., LTD.Inventors: Jingshan Shen, Yang He, Weiming Chen, Jianfeng Li, Guanghui Tian, Xudong Gong, Zhen Wang, Rongxia Zhang, Yongjian Liu, Hualiang Jiang
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Patent number: 11384073Abstract: The present disclosure relates to a maleate salt of a benzothiophene compound, a crystalline form thereof, and a use thereof. Specifically, the present disclosure relates to a compound represented by formula (I-A), a crystalline form A thereof, a preparation method of a pharmaceutical composition including the same, and a use of the pharmaceutical composition in the preparation of drugs for preventing or treating diseases of the central nervous system. The compound represented by formula (I-A) and the crystalline form A thereof in the present disclosure have excellent physical and chemical properties, high oral bioavailability, excellent drugability, and are well-suited for pharmaceutical preparation, application, and preservation.Type: GrantFiled: December 18, 2020Date of Patent: July 12, 2022Assignees: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, SUZHOU VIGONVITA LIFE SCIENCES CO., LTD., TOPHARMAN SHANGHAI CO., LTD.Inventors: Jingshan Shen, Yang He, Zhen Wang, Jianfeng Li, Yongjian Liu, Jin Suo, Guanghui Tian, Weiming Chen, Feipu Yang, Yu Wang, Xiangrui Jiang, Rongxia Zhang, Hualiang Jiang
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Publication number: 20210309648Abstract: The present disclosure relates to a maleate salt of a benzothiophene compound, a crystalline form thereof, and a use thereof. Specifically, the present disclosure relates to a compound represented by formula (I-A), a crystalline form A thereof, a preparation method of a pharmaceutical composition including the same, and a use of the pharmaceutical composition in the preparation of drugs for preventing or treating diseases of the central nervous system. The compound represented by formula (I-A) and the crystalline form A thereof in the present disclosure have excellent physical and chemical properties, high oral bioavailability, excellent drugability, and are well-suited for pharmaceutical preparation, application, and preservation.Type: ApplicationFiled: December 18, 2020Publication date: October 7, 2021Inventors: Jingshan Shen, Yang He, Zhen Wang, Jianfeng Li, Yongjian Liu, Jin Suo, Guanghui Tian, Weiming Chen, Feipu Yang, Yu Wang, Xiangrui Jiang, Rongxia Zhang, Hualiang Jiang
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Publication number: 20200140415Abstract: The present disclosure relates to a salt of phenyl pyrimidinone compound, a polymorph thereof and a pharmaceutical composition comprising the same and a use thereof, particularly relates to the hydrochlorate of phenyl pyrimidinone compound of following formula (I-A) and a pharmaceutically acceptable polymorph, solvate, hydrate, co-crystal, anhydrous substance, or amorphous form thereof, a pharmaceutical composition and a pharmaceutical unit dosage comprising the same, the preparing method and use thereof.Type: ApplicationFiled: January 7, 2020Publication date: May 7, 2020Applicants: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, SUZHOU VIGONVITA LIFE SCIENCES CO., LTD., TOPHARMAN SHANGHAI CO., LTD.Inventors: Jingshan Shen, Yang He, Weiming Chen, Jianfeng Li, Guanghui Tian, Xudong Gong, Zhen Wang, Rongxia Zhang, Yongjian Liu, Hualiang Jiang
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Patent number: 10341829Abstract: A directed data plan service-launching system includes an intelligent communication terminal, a virtual operator directed data plan system, a virtual operator billing system and an application background server, wherein the intelligent communication terminal calculates and stores mobile network data usage, and periodically uploads the same to the virtual operator directed data plan system with a certain time period, the virtual operator directed data plan system performs bill integration on data of the data usage to form and send a directed data plan bill to the virtual operator billing system, and the virtual operator billing system performs a charge deduction or billing with a specific price on the directed data plan bill; a primary operator billing system performing a charge deduction or billing with a specific price on the directed data plan bill; and an application background service system providing a background service to an application client side.Type: GrantFiled: July 6, 2016Date of Patent: July 2, 2019Assignee: SUZHOU SNAIL DIGITAL TECHNOLOGY CO., LTD.Inventors: Jimeng Song, Guanghui Tian, Chao Guo, Peng Jia
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Publication number: 20190014453Abstract: A directed data plan service-launching system includes an intelligent communication terminal, a virtual operator directed data plan system, a virtual operator billing system and an application background server, wherein the intelligent communication terminal calculates and stores mobile network data usage, and periodically uploads the same to the virtual operator directed data plan system with a certain time period, the virtual operator directed data plan system performs bill integration on data of the data usage to form and send a directed data plan bill to the virtual operator billing system, and the virtual operator billing system performs a charge deduction or billing with a specific price on the directed data plan bill; a primary operator billing system performing a charge deduction or billing with a specific price on the directed data plan bill; and an application background service system providing a background service to an application client side.Type: ApplicationFiled: July 6, 2016Publication date: January 10, 2019Inventors: Jimeng SONG, Guanghui TIAN, Chao GUO, Peng JIA
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Patent number: 10174011Abstract: The present invention provides a heterocyclic compound represented by the formula (I), its stereoisomers, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions thereof, and their use in preparing a medicament for the prevention and/or treatment of central nervous system disease.Type: GrantFiled: March 9, 2015Date of Patent: January 8, 2019Assignees: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, SUZHOU VIGONVITA LIFE SCIENCES CO., LTD., TOPHARMAN SHANDONG CO., LTD.Inventors: Hualiang Jiang, Zhen Wang, Jianfeng Li, Rongxia Zhang, Yang He, Yongjian Liu, Minghao Bi, Zheng Liu, Guanghui Tian, Weiming Chen, Feipu Yang, Chunhui Wu, Yu Wang, Xiangrui Jiang, Jingjing Yin, Guan Wang, Jingshan Shen
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Patent number: 10100044Abstract: The present invention relates to the methods for preparing brexpiprazole, the analogs, key intermediates, and salts thereof, specifically, the present invention relates to a new method for preparing brexpiprazole, the analogs, key intermediates, and salts thereof, and the key intermediates, and salts thereof provided during the preparation. The preparation method has a mild reaction condition, stable intermediate, easy operation, and uses cheap and easy-to-get reagents, thus it saves the synthesis cost, shortens the production cycle, improves the yield and product quality, and is suitable for mass production.Type: GrantFiled: October 20, 2014Date of Patent: October 16, 2018Assignees: Suzhou Vigonvita Life Sciences Co., Ltd., Topharman Shanghai Co., Ltd., Shanghai Institute of Materia Medica, Chinese Academy of SciencesInventors: Zheng Liu, Chunhui Wu, Yongjian Liu, Rongxia Zhang, Yang He, Guanghui Tian, Jingshan Shen
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Patent number: 10093679Abstract: Disclosed are aminosulfonyl-based compounds represented by the general formula I or tautomers, enantiomers, racemates or pharmaceutically acceptable salts thereof, a method for preparing the same, pharmaceutical compositions and uses thereof. The compounds can be used to treat epilepsy, convulsions, obesity and the like.Type: GrantFiled: September 11, 2015Date of Patent: October 9, 2018Assignees: SUZHOU VIGONVITA LIFE SCIENCES CO., LTD, SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, TOPHARMAN SHANGHAI CO., LTDInventors: Jingshan Shen, Zheng Liu, Zhen Wang, Guanghui Tian, Jianfeng Li, Xiaojun Yang
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Publication number: 20170298080Abstract: Disclosed are aminosulfonyl-based compounds represented by the general formula I or tautomers, enantiomers, racemates or pharmaceutically acceptable salts thereof, a method for preparing the same, pharmaceutical compositions and uses thereof. The compounds can be used to treat epilepsy, convulsions, obesity and the like.Type: ApplicationFiled: September 11, 2015Publication date: October 19, 2017Inventors: Jingshan SHEN, Zheng LIU, Zhen WANG, Guanghui TIAN, Jianfeng LI, Xiaojun YANG
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Publication number: 20170158680Abstract: The present invention provides a heterocyclic compound represented by the formula (I), its stereoisomers, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions thereof, and their use in preparing a medicament for the prevention and/or treatment of central nervous system disease.Type: ApplicationFiled: March 9, 2015Publication date: June 8, 2017Applicants: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, SUZHOU VIGONVITA LIFE SCIENCES CO., LTD., TOPHARMAN SHANDONG CO., LTD.Inventors: Hualiang JIANG, Zhen WANG, Jianfeng LI, Rongxia ZHANG, Yang HE, Yongjian LIU, Minghao BI, Zheng LIU, Guanghui TIAN, Weiming CHEN, Feipu YANG, Chunhui WU, Yu WANG, Xiangrui JIANG, Jingjing YIN, Guan WANG, Jingshan SHEN
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Patent number: 9527849Abstract: The present invention relates to new salts of pyrazolopyrimidinone represented by formula (I), and pharmaceutically acceptable polymorph, solvate, hydrate, dehydrate, co-crystallization, anhydrous, or amorphous form thereof, the pharmaceutical compositions, and a pharmaceutical unit dosage form containing the same, wherein x represents organic or inorganic acids, preferable maleic acid, succinic acid, methanesulfonic acid, hydrochloric acid, etc. The invention further relates to co-crystals or complexes of compounds of pyrazolopyrimidinone and pharmaceutical compositions containing the same. The present invention also relates to a process for the preparation, use thereof and pharmaceutical preparation containing the salts or crystalline forms.Type: GrantFiled: August 14, 2012Date of Patent: December 27, 2016Assignees: TOPHARMAN SHANGHAI CO., LTD., SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES TOPHARMAN SHANDONG CO., LTDInventors: Jianfeng Li, Guanghui Tian, Zhen Wang, Jin Suo, Xiangrui Jiang, Zheng Liu, Xiaojun Yang, Zhu Xie, Xianguo Zhao, Weiliang Zhu, Hualiang Jiang, Jingshan Shen
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Publication number: 20160272624Abstract: The present invention relates to the methods for preparing brexpiprazole, the analogs, key intermediates, and salts thereof, specifically, the present invention relates to a new method for preparing brexpiprazole, the analogs, key intermediates, and salts thereof, and the key intermediates, and salts thereof provided during the preparation. The preparation method has a mild reaction condition, stable intermediate, easy operation, and uses cheap and easy-to-get reagents, thus it saves the synthesis cost, shortens the production cycle, improves the yield and product quality, and is suitable for mass production.Type: ApplicationFiled: October 20, 2014Publication date: September 22, 2016Inventors: Zheng LIU, Chunhui WU, Yongjian LIU, Rongxia ZHANG, Yang HE, Guanghui TIAN, Jingshan SHEN
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Publication number: 20160102047Abstract: The present invention relates to a (2R,3R)-3-(3-substituted phenyl)-2-methyl n-pentanamide compounds as shown in the formula I and the preparation method thereof, wherein, the substituents are as defined in the specification, the present invention further relates to a use of the above compounds for the preparation of tapentadol II or its pharmaceutically acceptable salt, and the intermediates involved in the preparation processType: ApplicationFiled: December 18, 2015Publication date: April 14, 2016Inventors: Qiang ZHANG, Rongxia ZHANG, Guanghui TIAN, Jianfeng LI, Fuqiang ZHU, Xiangrui JIANG
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Patent number: 9249084Abstract: The present invention relates to a (2R,3R)-3-(3-substituted phenyl)-2-methyl n-pentanamide compounds as shown in the formula I and the preparation method thereof, wherein, the substituents are as defined in the specification, the present invention further relates to a use of the above compounds for the preparation of tapentadol II or its pharmaceutically acceptable salt, and the intermediates involved in the preparation process.Type: GrantFiled: January 31, 2012Date of Patent: February 2, 2016Assignees: Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Topharman Shanghai Co., Ltd.Inventors: Qiang Zhang, Rongxia Zhang, Guanghui Tian, Jianfeng Li, Fuqiang Zhu, Xiangrui Jiang, Jingshan Shen
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Patent number: 8884021Abstract: Provided is a process for preparing racemic nicotine from 1-methyl-3-nicotinoyl-2-pyrrolidone or a salt thereof using one-pot process. The process comprises the following steps: 1) in a reaction vessel, reacting 1-methyl-3-nicotinoyl-2-pyrrolidone or a salt thereof in the presence of a suitable solvent and a strong acid by heat; after the reaction is complete, cooling the same and adjusting the pH to 7-8 with alkali; and 2) directly adding a reductant into the above vessel, and after the reaction, purifying the product so as to obtain high purity racemic nicotine or a salt thereof.Type: GrantFiled: January 20, 2012Date of Patent: November 11, 2014Assignees: Topharman Shanghai Co., Ltd., Topharman Shandong Co., Ltd.Inventors: Guanghui Tian, Guan Wang, Xiaoguang Kong, Rongxia Zhang, Weiming Chen, Jingshan Shen
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Patent number: D973417Type: GrantFiled: July 10, 2020Date of Patent: December 27, 2022Assignee: Hamilton Beach Brands, Inc.Inventor: Guanghui Tian