Patents by Inventor Guido Jach
Guido Jach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230124898Abstract: An enzyme for reducing cystine to cysteine is a fusion protein that includes the protein activities of thioredoxin (protein i) having KEGG database number EC 1.8.4.8 or EC 1.8.4.10 and thioredoxin reductase (protein ii) having KEGG database number EC 1.8.1.9. The thioredoxin (protein i) is the protein activity of thioredoxin 1 from E. coli and the thioredoxin reductase (protein ii) is the protein activity of the thioredoxin reductase from E. coli. The activity of the fusion protein is at least 100% of the activity of a mixture of the same but unfused individual proteins i and ii. The fusion protein has the enzyme activity to reduce cystine to cysteine. The coding sequences (cds) responsible for the activity of protein i and ii has been fused.Type: ApplicationFiled: April 3, 2020Publication date: April 20, 2023Applicant: Wacker Chemie AGInventors: Carsten BORNHÖVD, Guido JACH, Ingrid TORRES MONROY, Peter WELTERS
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Patent number: 11326173Abstract: The present invention concerns a method of producing and enantiomerically pure alpha-ionone. Further, the invention concerns a nucleic acid that comprises a sequence that encodes a lycopene-epsilon-cyclase (EC), a lycopene-epsilon-cyclase (EC), plasmids, which encode components of the alpha-ionone biosynthesis and a microorganism that contains heterologous nucleotide sequences which encode the enzymes geranylgeranyl-diphosphate-synthase, isopentenyl-diphosphate-isomerase (IPI), phytoene desaturase-dehydrogenase (crtI), phytoene synthase (crtB), lycopene-epsilon-cyclase (EC) and carotenoid-cleavage-dioxygenase (CCD1). Further, the invention concerns a method of producing highly pure epsilon-carotene.Type: GrantFiled: August 28, 2015Date of Patent: May 10, 2022Assignee: PHYTOWELT GREENTECHNOLOGIES GMBHInventors: Guido Jach, Sanae Azdouffal, Katrin Schullehner, Peter Welters, Angela Goergen
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Patent number: 10227620Abstract: The invention relates to providing both fermentative and biotechnological methods for producing 3,4-methylized cinnamic acids, 3,4-methylized cinnamic acid esters, 3,4-dimethoxyphenethylamine, and 4-methylized cinnamic acid amides using a 4?-O-methyltransferase, optionally in combination with further enzymes, wherein the enzymes are selected by means of metabolic engineering and operation have been adapted by targeted optimization, and compositions obtained by means of the method. The invention further relates to vector systems, recombinant microorganisms or fungi, and specific nucleic acid segments and polypeptides.Type: GrantFiled: February 1, 2016Date of Patent: March 12, 2019Assignee: SYMRISE AGInventors: Gerhard Krammer, Jakob Peter Ley, Katrin Geißler, Torsten Geißler, Frauke Gomoll, Peter Welters, Guido Jach, Ludger Wessjohann
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Publication number: 20180251796Abstract: The present invention concerns a method of producing and enantiomerically pure alpha-ionone. Further, the invention concerns a nucleic acid that comprises a sequence that encodes a lycopene-epsilon-cyclase (EC), a lycopene-epsilon-cyclase (EC), plasmids, which encode components of the alpha-ionone biosynthesis and a microorganism that contains heterologous nucleotide sequences which encode the enzymes geranylgeranyl-diphosphate-synthase, isopentenyl-diphosphate-isomerase (IPI), phytoene desaturase-dehydrogenase (crtI), phytoene synthase (crtB), lycopene-epsilon-cyclase (EC) and carotenoid-cleavage-dioxygenase (CCD1). Further, the invention concerns a method of producing highly pure epsilon-carotene.Type: ApplicationFiled: August 28, 2015Publication date: September 6, 2018Inventors: Guido JACH, Sanae AZDOUFFAL, Katrin SCHULLEHNER, Peter WELTERS, Angela NATANEK
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Publication number: 20160281118Abstract: The invention relates to providing both fermentative and biotechnological methods for producing 3,4-methylized cinnamic acids, 3,4-methylized cinnamic acid esters, 3,4-dimethoxyphenethylamine, and 4-methylized cinnamic acid amides using a 4?-O-methyltransferase, optionally in combination with further enzymes, wherein the enzymes are selected by means of metabolic engineering and operation have been adapted by targeted optimization, and compositions obtained by means of the method. The invention further relates to vector systems, recombinant microorganisms or fungi, and specific nucleic acid segments and polypeptides.Type: ApplicationFiled: February 1, 2016Publication date: September 29, 2016Inventors: GERHARD KRAMMER, JAKOB PETER LEY, KATRIN GEIßLER, TORSTEN GEIßLER, FRAUKE GOMOLL, PETER WELTERS, GUIDO JACH, LUDGER WESSJOHANN
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Patent number: 9012227Abstract: The present invention relates to a cell, which has been genetically modified relative to its wild type, so that in comparison with its wild type it is able to produce more ?-aminocarboxylic acids, more ?-aminocarboxylic acid esters or more lactams derived from ?-aminocarboxylic acids, starting from carboxylic acids or carboxylic acid esters. Furthermore, the present invention relates to a method for the production of a genetically modified cell, the cells obtainable by this method, a method for the production of ?-aminocarboxylic acids, of ?-aminocarboxylic acid esters or of lactams derived from ?-aminocarboxylic acids, the ?-aminocarboxylic acids, ?-aminocarboxylic acid esters or lactams derived from ?-aminocarboxylic acids obtainable by this method, a method for the production of polyamides based on ?-aminocarboxylic acids or based on lactams and the polyamides obtainable by this method.Type: GrantFiled: December 12, 2008Date of Patent: April 21, 2015Assignee: Evonik Degussa GmbHInventors: Andreas Karau, Volker Sieber, Thomas Haas, Harald Haeger, Katrin Grammann, Bruno Buehler, Lars Blank, Andreas Schmid, Guido Jach, Bernd Lalla, Andreas Mueller, Katrin Schullehner, Peter Welters, Thorsten Eggert, Andrea Weckbecker
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Publication number: 20100324257Abstract: The present invention relates to a cell, which has been genetically modified relative to its wild type, so that in comparison with its wild type it is able to produce more ?-aminocarboxylic acids, more ?-aminocarboxylic acid esters or more lactams derived from ?-aminocarboxylic acids, starting from carboxylic acids or carboxylic acid esters. Furthermore, the present invention relates to a method for the production of a genetically modified cell, the cells obtainable by this method, a method for the production of ?-aminocarboxylic acids, of ?-aminocarboxylic acid esters or of lactams derived from ?-aminocarboxylic acids, the ?-aminocarboxylic acids, ?-aminocarboxylic acid esters or lactams derived from ?-aminocarboxylic acids obtainable by this method, a method for the production of polyamides based on ?-aminocarboxylic acids or based on lactams and the polyamides obtainable by this method.Type: ApplicationFiled: December 12, 2008Publication date: December 23, 2010Applicant: EVONIK DEGUSSA GmbhInventors: Andreas Karau, Volker Sieber, Thomas Haas, Harald Haeger, Katrin Grammann, Bruno Buehler, Lars Blank, Andreas Schmid, Guido Jach, Bernd Lalla, Andreas Mueller, Katrin Schullehner, Peter Welters, Thorsten Eggert, Andrea Weckbecker
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Publication number: 20010020300Abstract: Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinase (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFP).Type: ApplicationFiled: August 24, 1998Publication date: September 6, 2001Inventors: JURGEN LOGEMANN, GUIDO JACH, BIRGIT GORNHARDT, JOHN MUNDY, JEFF SCHELL, PETER ECKES, ILAN CHET
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Patent number: 6271442Abstract: Described are a method of producing pathogen-resistant plants in which a protein-synthesis inhibitor gene or a fusion product of the protein-synthesis inhibitor gene or of the protein-synthesis inhibitor protein with ligands permitting specific attachment to cells is introduced into the genotype of plants under the control of an active promotor, and the use of the protein-synthesis inhibitor protein obtained by introducing the protein-synthesis inhibitor gene into the bacterial overproducers for making pharmaceutical preparations.Type: GrantFiled: January 3, 1997Date of Patent: August 7, 2001Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschafen e.v.Inventors: Jeff Schell, Jürgen Logemann, Guido Jach, John Mundy
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Patent number: 6271438Abstract: Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinese (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFR).Type: GrantFiled: August 24, 1998Date of Patent: August 7, 2001Inventors: Jürgen Logemann, Guido Jach, Birgit Görnhardt, John Mundy, Jeff Schell, Peter Eckes, Ilan Chet
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Patent number: 5804184Abstract: Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinase (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFP).Type: GrantFiled: March 6, 1997Date of Patent: September 8, 1998Assignee: Max Planck Gesellschaft Zur Furderung der Wissen Schaften, e.v.Inventors: Jurgen Logemann, Guido Jach, Birgit Gornhardt, John Mundy, Jeff Schell, Peter Eckes
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Patent number: 5689045Abstract: Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinase (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFP).Type: GrantFiled: June 1, 1995Date of Patent: November 18, 1997Assignee: Max-Planck Gesellschaft zur Forderung Der WissenschaftenInventors: Jurgen Logemann, Guido Jach, Birgit Gornhardt, John Mundy, Jeff Schell, Peter Eckes, Ilan Chet
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Patent number: 5633442Abstract: Described are a method of producing pathogen-resistant plants in which a protein-synthesis inhibitor gene or a fusion product of the protein-synthesis inhibitor gene or of the protein-synthesis inhibitor protein with ligands permitting specific attachment to cells is introduced into the genotype of plants under the control of an active promotor, and the use of the protein-synthesis inhibitor protein obtained by introducing the protein-synthesis inhibitor gene into the bacterial overproducers for making pharmaceutical preparations.Type: GrantFiled: January 18, 1995Date of Patent: May 27, 1997Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.v.Inventors: Jeff Schell, Jurgen Logemann, Guido Jach, John Mundy
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Patent number: RE39238Abstract: Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinase (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFP).Type: GrantFiled: December 1, 2000Date of Patent: August 15, 2006Assignee: Max-Planck-Gesellschaft zür Forderung der Wissenschaften e.V.Inventors: Jürgen Logemann, Guido Jach, Birgit Görnhardt, John Mundy, Jeff Schell, Peter Eckes, Ilan Chet