Patents by Inventor Guillermo M. Ruiz Palacios
Guillermo M. Ruiz Palacios has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230101412Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.Type: ApplicationFiled: May 4, 2022Publication date: March 30, 2023Applicants: Children's Hospital Medical Center, The General Hospital Corporation d/b/a Massachusetts General Hospital, Instituto Nacional de Ciencias Medicas Y NutricionInventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Patent number: 11324765Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.Type: GrantFiled: May 28, 2021Date of Patent: May 10, 2022Assignees: Children's Hospital Medical Center, The General Hospital Corporation, Instituto Nacional de Ciencias Medicas Y NutricionInventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Publication number: 20210283155Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.Type: ApplicationFiled: May 28, 2021Publication date: September 16, 2021Applicants: Children's Hospital Medical Center, The General Hospital Corporation d/b/a Massachusetts General Hospital, Instituto Nacional de Ciencias Medicas Y NutricionInventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Patent number: 11058697Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.Type: GrantFiled: August 16, 2018Date of Patent: July 13, 2021Assignees: CHILDREN'S HOSPITAL MEDICAL CENTER, INSTITUTO NACIONAL DE CIENCIAS MEDICAS Y NUTRICION, THE GENERAL HOSPITAL CORPORATIONInventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Publication number: 20190099435Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.Type: ApplicationFiled: August 16, 2018Publication date: April 4, 2019Applicants: Children's Hospital Medical Center, The General Hospital Corporation d/b/a Massachusetts General Hospital, Instituto Nacional de Ciencias Medicas Y NutricionInventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Patent number: 10098903Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.Type: GrantFiled: April 30, 2015Date of Patent: October 16, 2018Assignees: Children's Hospital Medical Center, The General Hospital Corporation, Instituto Nacional de Ciencias Medicas Y NutricionInventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Publication number: 20150306120Abstract: A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.Type: ApplicationFiled: April 30, 2015Publication date: October 29, 2015Applicants: Children's Hospital Medical Center, The General Hospital Corporation, Instituto Nacional de Ciencias Medicas Y NutricionInventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Patent number: 9132142Abstract: An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).Type: GrantFiled: October 2, 2013Date of Patent: September 15, 2015Assignees: The General Hospital Corporation, Instituto Nacional de Ciencias Medicas Y Nutricion, Children's Hospital Medical CenterInventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Patent number: 9132143Abstract: An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).Type: GrantFiled: September 23, 2014Date of Patent: September 15, 2015Assignees: The General Hospital Corporation, Instituto Nacional de Ciencias Medicas Y Nutricion, Children's Hospital Medical CareInventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Patent number: 9034847Abstract: A method of inhibiting inflammation in a subject comprising the administration of milk oligosaccharides or glycoconjugates containing milk oligosaccharides is disclosed.Type: GrantFiled: July 2, 2010Date of Patent: May 19, 2015Assignees: Children's Hospital Medical Center, The General Hospital Corporation, Instituto Nacional de Ciencias Medicas Y NutricionInventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Publication number: 20150079055Abstract: An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).Type: ApplicationFiled: September 23, 2014Publication date: March 19, 2015Applicants: Children's Hospital Medical Center, The General Hospital Corporation, Instituto Nacional de Ciencias Medicas Y NutricionInventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Publication number: 20140140970Abstract: An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).Type: ApplicationFiled: October 2, 2013Publication date: May 22, 2014Applicants: Children's Hospital Medical Center, Instituto Nacional de Ciencias Medicas Y Nutricion, The General Hospital CorporationInventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Publication number: 20120202753Abstract: A method of inhibiting inflammation in a subject comprising the administration of milk oligosaccharides or glycoconjugates containing milk oligosaccharides is disclosed.Type: ApplicationFiled: July 2, 2010Publication date: August 9, 2012Applicants: Instituto Nacional de Ciencias Medicas Y Nutricion, The General Hospital Corporation d/b/a Massachusetts General Hospital, (CCHMC)Inventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Publication number: 20110207659Abstract: Oligosaccharides and oligosaccharides linked to backbones such as proteins, methods for making such oligosaccharides and methods for using them to treat and/or prevent various disorders are described.Type: ApplicationFiled: February 22, 2011Publication date: August 25, 2011Applicants: Children's Hospital Medical Center, University of Massachusetts, Instituto Nacional de Ciencias Medicas Y NutricionInventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Publication number: 20110177035Abstract: An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).Type: ApplicationFiled: January 14, 2011Publication date: July 21, 2011Inventors: Ardythe L. Morrow, Guillermo M. Ruiz-Palacios, David S. Newburg
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Patent number: 7893041Abstract: Oligosaccharides and oligosaccharides linked to backbones such as proteins, methods for making such oligosaccharides and methods for using them to treat and/or prevent various disorders are described.Type: GrantFiled: December 6, 2004Date of Patent: February 22, 2011Assignees: Children's Hospital Medical Center, Instituto Nacional De Ciencias Medicas Y Nutricion, University of MassachusettsInventors: Ardythe L. Morrow, David S. Newburg, Guillermo M. Ruiz-Palacios
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Patent number: 7871785Abstract: An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1 , H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).Type: GrantFiled: September 5, 2008Date of Patent: January 18, 2011Assignees: Children's Hospital Medical Center, The General Hospital Corporation, Instituto Nacional De Ciencias Medicas y NutricionInventors: Ardythe L. Morrow, Guillermo M. Ruiz-Palacios, David S. Newburg
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Publication number: 20090191551Abstract: An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and comparing the measured level of the at least one secretor antigen to a predetermined value or a predetermined range of values. Among the secretor antigens which can be measured are: the H-1, H-2, Lewisb and Lewisy antigens and derivatives thereof (e.g., a sialylated form of Lewis a, Lewis x, Lewis b, Lewis y; H-1, H-2, Lewis a, Lewis x, Lewis b or Lewis y).Type: ApplicationFiled: September 5, 2008Publication date: July 30, 2009Inventors: Ardythe L. Morrow, Guillermo M. Ruiz-Palacios, David S. Newburg
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Publication number: 20020019991Abstract: The subject intention relates to compositions containing at least one fucose residue in an &agr;1-2 linkage and uses thereof. In particular, such compositions can be used in the treatment and prevention of gastrointestinal infections caused by, for example, Escherichia coil and Vibrio cholerae. The subject invention also encompasses methods of screening for the above compositions. Additionally, the subject invention includes vaccines.Type: ApplicationFiled: April 30, 1998Publication date: February 14, 2002Applicant: ABBOTT LABORATORIESInventors: PEDRO A. PRIETO, GUILLERMO M. RUIZ-PALACIOS
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Process for obtaining an antigenic reagent useful for the indirect determination of Salmonella typhi
Patent number: 5405754Abstract: The invention described herein consists of a process for preparing an antigenic reagent useful for the indirect determination of Salmonella typhi, the organism that is the causal agent of typhoid fever (TF). The invention consists on the following steps: to grow Salmonella typhi in a culture medium, characterized by containing a free-iron chelator, which generates a specific S. typhi outer membrane protein (OMP) pattern, OMPs that are used as a selective antigen for the detection of specific serum antibodies, by an immunoassay technique (ELISA).Type: GrantFiled: March 21, 1991Date of Patent: April 11, 1995Assignee: Universidad Nacional Autonoma de MexicoInventors: Edmundo Calva-Mercado, Guillermo M. Ruiz Palacios, Antonio V. Rodriguez, Yolanda L. Vidal