Abstract: Apparatus and method are disclosed for closing and sealing a molded plastic article formed by expanding a heated plastic parison within a chamber or cavity defined by a plurality of mold sections. The article is closed and sealed by at least one movable sealing member which has a protruding pinch surface to weaken or sever the parison and recess surface portions selectively above or below the protruding pinch surface which provide plastic-receiving reservoirs that aid in the formation of an unobtrusive seal adjacent the surface of the article. The sealing member may also include parison engaging seat or heel portions which further aid in the sealing operation. The temperature of the mold sections adjacent the sealing operation is controlled to selectively retard the cooling of the parison, which is in direct contact with the cavity surface, to maintain the parison at a sufficiently elevated temperature to permit closing and sealing by the sealing member.

Abstract: There is disclosed herein a method for collecting blood plasma in plastic bottles wherein the blood plasma can be stored for periods of time and can then be utilized in obtaining blood fractions therefrom. The method includes the concept of filling a previously sterilized and hermetically sealed bottle with blood plasma. The bottle, after filling, is sealed at the neck portion thereof by means of heat sealing. The portion of the bottle above the heat seal is severed. Thereafter, the filled bottle is frozen and transported to the site for use. The bottle containing the plasma is then thawed and conveyed to a plasma removing device. The plasma is removed by severing a portion of the bottom of the plastic bottle, thereby permitting the liquefied plasma to flow therefrom into a collection vat.

Abstract: There is disclosed herein a method for collecting blood plasma in plastic bottles wherein the blood plasma can be stored for periods of time and can then be utilized in obtaining blood fractions therefrom. The method includes the concept of filling a previously sterilized and hermetically sealed bottle with blood plasma. The bottle, after filling, is sealed at the neck portion thereof by means of heat sealing. The portion of the bottle above the heat seal is severed. Thereafter, the filled bottle is frozen and transported to the site for use. The bottle containing the plasma is then thawed and conveyed to a plasma removing device. The plasma is removed by severing a portion of the bottom of the plastic bottle, thereby permitting the liquefied plasma to flow therefrom into a collection vat.