Abstract: Provided herein are Claudin 18.2 binding agents and chimeric antigen receptors (CARs) comprising a Claudin 18.2 binding molecule that specifically binds to Claudin 18.2; and immune cells comprising these Claudin 18.2-specific CARs, e.g., CAR-T cells. Also provided are methods of making and using Claudin 18.2-specific CARs and Claudin 18.2 binding agents, and immune cells comprising Claudin 18.2-specific CARs.

Abstract: A method and apparatus for keeping data consistent across different storage systems are provided. The method includes: when a first storage system is updated, processing first data to be unreadable, and generating or updating a version number corresponding to a first primary key; when the first data is unable to be read from a second storage system, acquiring a latest version number of the first primary key, and reading second data from the first storage system; comparing the acquired version number with the latest version number of the first primary key; if consistent, updating the second data into the second storage system using an atomic operation, and updating the version number corresponding to the first primary key; and if inconsistent, re-performing the step of acquiring the latest version number of the first primary key and reading the second data from the first storage system.