Abstract: The present disclosure relates to a method and apparatus for a funnel assembly for use in a beverage brewing apparatus. The funnel assembly may include an insert that is retained in the funnel assembly to contain a powdered or other similar substance for mixing with liquid within the insert. The insert is configured to extend within a cavity of the funnel assembly and is configured to permit mixing of the substance with the liquid before dispensing the mixture into a portion of the funnel assembly. The insert may include a rim or liquid shield, with at least a portion of the rim or liquid shield engaging a portion of the funnel assembly to retain the insert within the funnel assembly. The insert may further include a flow guide adjacent a drainage aperture, the flow guide at least partially directing the flow of mixture from the insert into a portion of the funnel assembly.

Abstract: The present disclosure is of an atmospheric characterization system that has a central processing board that has a first and a second communication interface. Further, the atmospheric characterization system further has a first precision temperature sensor that is communicatively coupled to the central processing board via the first communication interface and positioned a distance from a first side of the processing board, wherein the precision temperature measures a first temperature and transfers data indicative of the first temperature to the central processing board.

Abstract: An antibacterial interior component, such as a door handle component, is provided in a vehicle that includes at least one touch surface in a confined space having a shadowed region. A light source includes a light emitting diode (LED) that generates light having a wavelength of ?about 375 nm to ?about 425 nm directed towards the at least one touch surface for killing bacteria. A thermally conductive component in heat transfer relationship with the light source to transfer heat to a heat sink either in or adjacent to the antibacterial interior component. Methods of operating the self-sanitizing antibacterial interior component are also provided.

Abstract: The present disclosure relates to a method and apparatus for a funnel assembly for use in a beverage brewing apparatus. The funnel assembly may include an insert that is retained in the funnel assembly to contain a powdered or other similar substance for mixing with liquid within the insert. The insert is configured to extend within a cavity of the funnel assembly and is configured to permit mixing of the substance with the liquid before dispensing the mixture into a portion of the funnel assembly. The insert may include a rim or liquid shield, with at least a portion of the rim or liquid shield engaging a portion of the funnel assembly to retain the insert within the funnel assembly. The insert may further include a flow guide adjacent a drainage aperture, the flow guide at least partially directing the flow of mixture from the insert into a portion of the funnel assembly.

Abstract: Amino acid sequences of antibodies can be generated using a generative adversarial network that includes a first generating component that generates amino acid sequences of antibody light chains and a second generating component generates amino acid sequences of antibody heavy chains. Amino acid sequences of antibodies can be produced by combining the respective amino acid sequences produced by the first generating component and the second generating component. The training of the first generating component and the second generating component can proceed at different rates. Additionally, the antibody amino acids produced by combining amino acid sequences from the first generating component and the second generating component may be evaluated according to complentarity-determining regions of the antibody amino acid sequences.

Abstract: A filter adapter removably attachable to a faucet assembly of a beverage server is disclosed. The filter adapter filters elements flowing from the beverage server and includes a body having an opening, an outlet passage, and a filter material. The filter material is seated inside the body through the opening and along the outlet passage. The filter material captures undesirable elements, thereby preventing these elements from dispensing into a beverage container.

Abstract: The present disclosure provides optimized broadly-neutralizing anti-HIV antibodies, having modified light chain variable regions and/or heavy chain variable regions leading to improved biophysical characteristics. The present disclosure also provides methods for producing these anti-HIV antibodies and methods of use thereof.

Abstract: The present disclosure provides various components entrapped within a cross-linked alginate matrix and products including such component-containing, alginate-based matrices. The disclosure also includes a method for entrapping the components, including mixing the component or components with alginate in water, contacting the mixture with a cation to cross-link the alginate, and removing at least a portion of the water therefrom. The resulting component-containing alginate-based material can then be incorporated within various products, e.g., consumable products such as aerosol-generating devices and components, oral products, and conventional smoking articles.

Abstract: A cup anemometer providing accurate wind speed measurement in a cost-effective configuration. A rotor of the anemometer, e.g. a single-piece molded rotor, may be assembled to a shaft using a cap. In some embodiments, the hub of the rotor and the cap provide symmetry in the area of the cups and arms of the rotor and/or the bottom of the hub and the top of the cap may be positioned above and below, respectively, the planes defined by the tops and bottoms, respectively, of cups of the rotor. In some embodiments, each of the of the cups may be generally conical having a cone angle of nominally 114 degrees and/or each of the arms of the rotor may have a front surface that is co-planar with a front surface of an associated one of the cups.

Abstract: Featured are PGDM1400 variant antibodies or fragments thereof, which can be administered, e.g., as antibody therapies for treating human immunodeficiency virus (HIV) infection. In particular, featured are methods of treating or curing subjects infected with HIV and/or preventing HIV infections in subjects at risk of HIV transmission using the PGDM1400 variant antibodies or fragments thereof.

Abstract: A retaining ring configured for in-field repair of a fuel injector sleeve upper seal leak, comprising: a circular side wall comprising a barrel-shaped outer surface and a substantially cylindrical inner surface; wherein the outer surface comprises a lower curved portion and a central portion having a curvature that is less pronounced than the lower curved portion; and wherein the lower curved portion is configured to guide the retaining ring into the fuel injector sleeve and the circular side wall has an outer diameter at the central portion that is larger than an inner diameter of the fuel injector sleeve at a location of the upper seal leak such that the retaining ring forces the fuel injector sleeve outwardly at the location of the upper seal leak as the retaining ring is moved into an installed position.

Abstract: A spray head assembly for use with a beverage brewer includes a spray head and an adapter. The spray head includes a back plate having a turn mechanism. The adapter includes a body having an outer portion and a threaded inner portion. The body has an opening through the threaded inner portion that is attachable to a valve of the beverage maker. The outer portion of the body includes ears attachable to the backer plate of the spray head through the turn mechanism.

Abstract: Featured are PGT121 variant antibodies or fragments thereof, which can be administered, e.g., as antibody therapies for treating human immunodeficiency virus (HIV) infection. In particular, featured are methods of treating subjects infected with HIV and/or blocking HIV infections in subjects at risk of HIV transmission using the PGT121 variant antibodies or fragments thereof.

Abstract: The present invention relates to an automated liquid transmission cell system capable of transferring solvents and samples to clean and fill the transmission cells. Three valves allow a plurality of system configurations to perform a variety of flushing and filling processes by changing the position of each valve. A plurality of tubes are connected to two of the valves such that changing the valve positions will redirect fluid transmission paths.

Abstract: The present invention relates to a chemical vapor-sensor bag with an integrated sensor array to verify the presence of specific chemical vapors inside a sealed bag. In an exemplary embodiment, a device can be sealed within a vapor-sensor bag to allow the device to be transported to and tested for contaminants at the point of use by an end user of the device. In another exemplary embodiment, a device can be coupled to a gas port on a vapor-sensor bag to allow gas within the device to be tested for contaminants. In another exemplary embodiment, gas from a device can be streamed through vapor-sensor bag by coupling the device to a first gas port on a vapor-sensor bag and allowing gas to exit the bag through a second gas port.

Abstract: In one embodiment, a vacuum-actuated surgical grasper includes a suction head adapted to interface with patient tissue, a suction tube connected to and in fluid communication with the suction head, and a handle connected to the suction tube, the handle comprising an internal passage in fluid communication with the suction tube through which fluid from the suction tube can flow and a pivotable actuation lever that controls this flow through the passage.

Abstract: A method of preparing a low calorie, Lactose-free and Phosphorus-reduced milk with multiple filtration, centrifugation, carbonation and phase separation steps to remove Lactose and Phosphorus from milk including skim milk. The method includes a filtration apparatus to employ ultrafiltration to remove Lactose and any component of Lactose. Ultra-Centrifugation is used additionally to increase and complete the removal of Lactose and to facilitate the reduction of Phosphorous in the final milk preparation. The process eliminates the conventional use of lactase enzyme to hydrolyze Lactose into its simple sugar components.

Abstract: Contaminant cleaning systems and related methods are provided. Exemplary embodiments include a reactive substance generator to produce or transfer reactive substance(s) that react with contaminant(s) on an item into a cleaning chamber. An analysis section can be attached to the cleaning chamber to perform gas analysis on gas samples brought into the analysis chamber that measure reaction byproducts from the reactive substance(s) interaction with the contaminants. An exemplary valve system can selectively couple the reactive substance generator, the analysis section, and the cleaning chamber. An exemplary pumping system, in combination with the valve system, can selectively generate differential pressure/vacuum levels between the reactive substance generator vs cleaning chamber as well as between the cleaning chamber and analysis section. For example, the analysis chamber can be configured to have a higher vacuum than the cleaning chamber to facilitate passage of gas test samples into the analysis chamber.

Abstract: In one embodiment, a vacuum-actuated surgical grasper includes a suction head adapted to interface with patient tissue, a suction tube connected to and in fluid communication with the suction head, and a handle connected to the suction tube, the handle comprising an internal passage in fluid communication with the suction tube through which fluid from the suction tube can flow and a pivotable actuation lever that controls this flow through the passage.