Abstract: The present invention provides core-stabilized microcapsules, wherein said core comprises at least one active agent encapsulated within an inorganic oxide shell, processes for their preparations, comparisons comprising them and uses thereof.

Abstract: A medical display processing device and a method of reusing data includes acquiring, over time via electrodes, electrical signals each acquired via one of the electrodes and indicating electrical activity at a location of a portion of patient anatomy in a 3D space. Electrical signal data, corresponding to the electrical signals, is filtered according to first filter parameter settings and first mapping information is generated for displaying a map of the portion of patient anatomy and the filtered electrical signal data. An indication of a region of the portion of patient anatomy on the map is received and second mapping information is generated for displaying, at the region on the map, a portion of the electrical signal data previously filtered from display.

Abstract: Methods, apparatus, and systems for medical procedures are disclosed herein and include sensing a plurality of tissue electrical potentials at an organ area of an organ, by one or more electrodes on a catheter, determining a number of peak electrical potentials from the plurality of first tissue electrical potentials such that the a peak electrical potential exceeds a potential threshold, determining a first visual characteristic based on the number of peak electrical potential and displaying a rendering of the organ comprising the organ area such that the rendering of the first organ area comprises the first visual characteristic.

Abstract: Apparatus for assessing scarring of cardiac tissue, consisting of a probe and a processor. The probe has one or more electrodes, which are configured to contact the tissue at a plurality of positions and to sense respective voltages in the tissue at the positions. The processor receives the respective voltages, and computes a triangular mesh that is representative of a surface of the tissue and that consists of multiple triangles having vertices corresponding to the positions contacted by the one or more electrodes. The processor calculates respective scar areas within the triangles by comparing the respective voltages sensed at the positions corresponding to the vertices to a predefined range of the voltages that is associated with scarring, and computes a sum of the respective areas. The processor compares the sum to a total area of the triangles so as to assess a degree of the scarring of the tissue.

Abstract: The invention relates to a process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid, water-insoluble particulate matter with an ionic additive and an aqueous medium to obtain a dispersion of said particulate matter having positive charges on its surface; (b) subjecting the particulate matter to a coating procedure comprising precipitating a metal oxide salt onto the surface of the particulate matter to form a metal oxide layer thereon to thereby obtain particulate matter coated by a metal oxide coating layer; (c) repeating step (b) at least 4 more times; and (d) aging said coating layer. The invention further relates to particles comprising a particulate matter coated by a metal oxide layer, to a use of the particles for topical administration, and to a method for preventing, reducing, or eliminating pests at a locus, using the particles.

Abstract: The present invention relates to pharmaceutical compositions for topical use (including also dermatological compositions), for treating skin conditions and afflictions, such as rosacea and symptoms and conditions associated there from.

Abstract: The invention relates to a process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid, water-insoluble particulate matter with an ionic additive and an aqueous medium to obtain a dispersion of said particulate matter having positive charges on its surface; (b) subjecting the particulate matter to a coating procedure comprising precipitating a metal oxide salt onto the surface of the particulate matter to form a metal oxide layer thereon to thereby obtain particulate matter coated by a metal oxide coating layer; (c) repeating step (b) at least 4 more times; and (d) aging said coating layer. The invention further relates to particles comprising a particulate matter coated by a metal oxide layer, to a use of the particles for topical administration, and to a method for preventing, reducing, or eliminating pests at a locus, using the particles.

Abstract: An ECG data management system is disclosed which includes a first memory portion configured to store ECG data having values corresponding to electrical signals of a heart acquired over time via a plurality of electrodes disposed at different areas of the heart. The system also includes a second memory portion configured to store the ECG data and a processing device configured to manage mapping of the ECG data by performing a mapping procedure including generating map data and one or more maps from the ECG data for display; concurrently storing the ECG data in the first memory portion and the second memory portion; and in response to a request to export the ECG data, stopping the storing of the ECG data in the second memory portion and synchronizing the ECG data stored in the second memory portion with the map data while continuing to perform the mapping procedure.

Abstract: Apparatus for assessing scarring of cardiac tissue, consisting of a probe and a processor. The probe has one or more electrodes, which are configured to contact the tissue at a plurality of positions and to sense respective voltages in the tissue at the positions. The processor receives the respective voltages, and computes a triangular mesh that is representative of a surface of the tissue and that consists of multiple triangles having vertices corresponding to the positions contacted by the one or more electrodes. The processor calculates respective scar areas within the triangles by comparing the respective voltages sensed at the positions corresponding to the vertices to a predefined range of the voltages that is associated with scarring, and computes a sum of the respective areas. The processor compares the sum to a total area of the triangles so as to assess a degree of the scarring of the tissue.

Abstract: Apparatus for assessing scarring of cardiac tissue, consisting of a probe and a processor. The probe has one or more electrodes, which are configured to contact the tissue at a plurality of positions and to sense respective voltages in the tissue at the positions. The processor receives the respective voltages, and computes a triangular mesh that is representative of a surface of the tissue and that consists of multiple triangles having vertices corresponding to the positions contacted by the one or more electrodes. The processor calculates respective scar areas within the triangles by comparing the respective voltages sensed at the positions corresponding to the vertices to a predefined range of the voltages that is associated with scarring, and computes a sum of the respective areas. The processor compares the sum to a total area of the triangles so as to assess a degree of the scarring of the tissue.

Abstract: An insulating concrete form system for the construction of insulated concrete walls, floors or roofs, the system comprising: at least one first panel; at least one second panel configured to be placed opposite to the at least one first panel, and a plurality of spacers configured to interconnect the at least one first panel and the at least one second panel while defining a space between the at least one first panel and the at least one second panel. A method for constructing a concrete wall, floor or roof, as well as additional embodiments of the system and method, are provided herein.

Abstract: A probe generates location signals, and has an electrode at a distal end which acquires from heart chamber surface positions electrical signals due to a conduction wave traversing the surface. A processor derives LATs from the electrical signals, calculates a first time difference between LATs at a first pair of positions and a second time difference between LATs at a second pair of positions. The processor calculates first and second LAT-derived distances as products of the first and second time differences with a conduction wave velocity, identifies an arrhythmia origin at a surface location where a first difference in distances from the location to the first pair of the positions is equal to the first LAT-derived distance, and a second difference in distances from the location to the second pair of the positions is equal to the second LAT-derived distance, and marks the origin on a surface representation.

Abstract: The present invention provides core-stabilized microcapsules, wherein said core comprises at least one active agent encapsulated within an inorganic oxide shell, processes for their preparations, comparisons comprising them and uses thereof.

Abstract: A method including calculating, at multiple intra-cardiac locations, respective average atrial fibrillation cycle-length (AFCL) values. A determination is made as to whether the calculated average AFCL values are indicative of a regular atrial fibrillation (AF) activity. Gradients between pairs of the average AFCL values are calculated for a plurality of average AFCL values that are determined to be indicative of regular AF activity. The calculated AFCL gradients are presented to a user, overlaid on a map of at least a portion of the heart.

Abstract: A process for preparing nanocapsules having a core-shell structure, comprising: (a) preparing an oil-in-water emulsion by emulsification of an oily phase that comprises a core material, in an aqueous phase, under high shear forces, wherein one or both of the oily phase, and the aqueous phase comprises a sol-gel precursor; (b) subjecting the emulsion obtained in (a) to a high pressure homogenization to obtain a nano-emulsion; and (c) applying conditions for hydrolyzing and polycondensing the sol-gel precursor to obtain nanocapsules having a metal oxide shell encapsulating the core material, said nanocapsules have a particle size distribution of: d10=10-80 nm, d50=30-200 nm, and d90=70-500 nm, in diameter. The invention also relate to nanocapsules having the above particle size distribution and to composition comprising the nanocapsules.

Abstract: The present invention provides core-stabilized microcapsules, wherein said core comprises at least one active agent encapsulated within a metal oxide shell, processes for their preparations, comparisons comprising them and uses thereof.

Abstract: A coordinate system registration module, including radiopaque elements arranged in a fixed predetermined pattern and configured, in response to the radiopaque elements generating a fluoroscopic image, to define a position of the module in a fluoroscopic coordinate system of reference. The module further includes one or more connections configured to fixedly connect the module to a magnetic field transmission pad at a predetermined location and orientation with respect to the pad, so as to characterize the position of the registration module in a magnetic coordinate system of reference defined by the magnetic field transmission pad.

Abstract: An ECG data management system is disclosed which includes a first memory portion configured to store ECG data having values corresponding to electrical signals of a heart acquired over time via a plurality of electrodes disposed at different areas of the heart. The system also includes a second memory portion configured to store the ECG data and a processing device configured to manage mapping of the ECG data by performing a mapping procedure including generating map data and one or more maps from the ECG data for display; concurrently storing the ECG data in the first memory portion and the second memory portion; and in response to a request to export the ECG data, stopping the storing of the ECG data in the second memory portion and synchronizing the ECG data stored in the second memory portion with the map data while continuing to perform the mapping procedure.

Abstract: The present invention provides core-stabilized microcapsules, wherein said core comprises at least one active agent encapsulated within an inorganic oxide shell, processes for their preparations, comparisons comprising them and uses thereof.

Abstract: The present invention provides core-stabilized microcapsules, wherein said core comprises at least one active agent encapsulated within a inorganic oxide shell, processes for their preparations, comparisons comprising them and uses thereof.