Patents by Inventor Haiqun Liu

Haiqun Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-SERUM ALBUMIN BINDING VARIANTS
    Publication number: 20200283512
    Abstract: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-11, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
    Type: Application
    Filed: May 20, 2020
    Publication date: September 10, 2020
    Inventors: Elena DE ANGELIS, Carolyn ENEVER, Haiqun LIU, Oliver SCHON
  • Anti-serum albumin binding variants
    Patent number: 10696738
    Abstract: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-11, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: June 30, 2020
    Assignee: Glaxon Group Limited
    Inventors: Elena De Angelis, Carolyn Enever, Haiqun Liu, Oliver Schon
  • ANTI-SERUM ALBUMIN BINDING VARIANTS
    Publication number: 20170298121
    Abstract: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-11, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
    Type: Application
    Filed: February 2, 2017
    Publication date: October 19, 2017
    Inventors: Elena DE ANGELIS, Carolyn ENEVER, Haiqun LIU, Oliver SCHON
  • Anti-serum albumin binding variants
    Patent number: 9751935
    Abstract: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-14, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: September 5, 2017
    Assignee: Glaxo Group Limited
    Inventors: Elena De Angelis, Carolyn Enever, Haiqun Liu, Oliver Schon
  • Anti-serum albumin binding variants
    Patent number: 9534043
    Abstract: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-11, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: January 3, 2017
    Assignee: Glaxo Group Limited
    Inventors: Elena De Angelis, Carolyn Enever, Haiqun Liu, Christopher Plummer, Oliver Schon
  • ANTI-SERUM ALBUMIN BINDING VARIANTS
    Publication number: 20160075774
    Abstract: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-14, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
    Type: Application
    Filed: September 23, 2015
    Publication date: March 17, 2016
    Inventors: Elena DE ANGELIS, Carolyn Enever, Haiqun Liu, Oliver Schon
  • ANTI-SERUM ALBUMIN BINDING VARIANTS
    Publication number: 20160052998
    Abstract: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
    Type: Application
    Filed: February 27, 2015
    Publication date: February 25, 2016
    Inventors: Haren ARULANANTHAM, Thil Batuwangala, Elena De Angelis, Carolyn Enever, Haiqun Liu, Oliver Schon
  • Anti-serum albumin binding variants
    Patent number: 9175071
    Abstract: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-14, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: November 3, 2015
    Assignee: GLAXO GROUP LIMITED
    Inventors: Elena De Angelis, Carolyn Enever, Haiqun Liu, Oliver Schon
  • ANTI-SERUM ALBUMIN BINDING VARIANTS
    Publication number: 20150284454
    Abstract: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-11, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
    Type: Application
    Filed: April 21, 2015
    Publication date: October 8, 2015
    Inventors: ELENA DE ANGELIS, CAROLYN ENEVER, HAIQUN LIU, OLIVER SCHON, MALGORZATA PUPECKA-SWIDER
  • Anti-serum albumin binding variants
    Patent number: 9040668
    Abstract: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-11, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: May 26, 2015
    Assignee: Glaxo Group Limited
    Inventors: Elena De Angelis, Carolyn Enever, Haiqun Liu, Oliver Schon, Malgorzata Pupecka-Swider
  • Anti-serum albumin binding variants
    Patent number: 9012609
    Abstract: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: April 21, 2015
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Haren Arulanantham, Thil Dinuk Batuwangala, Elena De Angelis, Carolyn Enever, Haiqun Liu, Oliver Schon
  • ANTI-SERUM ALBUMIN BIDING VARIABLE DOMAINS
    Publication number: 20140140996
    Abstract: The invention relates to improved anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variable domains, compositions, nucleic acids, vectors and hosts.
    Type: Application
    Filed: January 30, 2014
    Publication date: May 22, 2014
    Applicant: Glaxo Group Limited
    Inventors: Edward COULSTOCK, Elena De Angelis, Haiqun Liu, Oliver Schon
  • Anti-serum albumin single variable domains
    Patent number: 8679496
    Abstract: The invention relates to improved anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variable domains, compositions, nucleic acids, vectors and hosts.
    Type: Grant
    Filed: July 14, 2010
    Date of Patent: March 25, 2014
    Assignee: Glaxo Group Limited
    Inventors: Edward Coulstock, Elena De Angelis, Haiqun Liu, Oliver Schon
  • ANTI-SERUM ALBUMIN BINDING SINGLE VARIABLE DOMAINS
    Publication number: 20130266567
    Abstract: The invention relates to improved anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variable domains, compositions, nucleic acids, vectors and hosts.
    Type: Application
    Filed: December 1, 2011
    Publication date: October 10, 2013
    Inventors: Haren Arulanantham, Haiqun Liu, Oliver Schon
  • ANTI-SERUM ALBUMIN BINDING VARIANTS
    Publication number: 20130230519
    Abstract: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-14-10, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
    Type: Application
    Filed: August 12, 2011
    Publication date: September 5, 2013
    Inventors: Elena De Angelis, Carolyn Enever, Haiqun Liu, Malgorzata Pupecka-Swider, Oliver Schon
  • Methods of antagonizing the binding of CD40 to CD40L with CD40L-specific monovalent polypeptides in autoimmune individuals
    Patent number: 8524236
    Abstract: The invention relates to antibody polypeptides that monovalently bind CD40L. Antibody polypeptides that are monovalent for binding of CD40L can inhibit CD40L activity while avoiding potential undesirable effects that can occur with antibodies capable of divalent or multivalent binding of CD40L. In one aspect, a monovalent anti-CD40L antibody polypeptide consists of or comprises a single immunoglobulin variable domain that specifically binds and antagonizes the activity of CD40L, preferably without substantially agonizing CD40 and/or CD40L activity. In another aspect, the monovalent anti-CD40L antibody polypeptide is a human antibody polypeptide. The invention further encompasses methods of antagonizing CD40/CD40L interactions in an individual and methods of treating diseases or disorders involving CD40/CD40L interactions, the methods involving administering a monovalent anti-CD40L antibody polypeptide to the individual.
    Type: Grant
    Filed: September 16, 2005
    Date of Patent: September 3, 2013
    Assignee: Domantis Limited
    Inventors: Steven Grant, Haiqun Liu, Kevin Moulder
  • ANTI-SERUM ALBUMIN BINDING VARIANTS
    Publication number: 20130202597
    Abstract: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
    Type: Application
    Filed: August 12, 2011
    Publication date: August 8, 2013
    Applicant: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Haren Arulanantham, Thil Dinuk Batuwangala, Elena De Angelis, Carolyn Enever, Haiqun Liu, Oliver Schon
  • ANTI-SERUM ALBUMIN BINDING VARIANTS
    Publication number: 20130129746
    Abstract: The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-11, as well as ligands and drug conjugates comprising such variants, compositions, nucleic acids, vectors and hosts.
    Type: Application
    Filed: May 20, 2011
    Publication date: May 23, 2013
    Inventors: Elena De Angelis, Carolyn Enever, Haiqun Liu, Oliver Schon, Malgorzata Pupecka-Swider
  • ANTI-SERUM ALBUM SINGLE VARIABLE DOMAINS
    Publication number: 20120114647
    Abstract: The invention relates to improved anti-serum albumin immunoglobulin single variable domains, as well as ligands and drug conjugates comprising such variable domains, compositions, nucleic acids, vectors and hosts.
    Type: Application
    Filed: July 14, 2010
    Publication date: May 10, 2012
    Inventors: Edward Coulstock, Elena De Angelis, Haiqun Liu, Oliver Schon
  • Antibodies against antigens
    Patent number: 8092800
    Abstract: This invention relates to domain antibodies. In particular, it relates to domain antibodies (dAbs) that recognize virulence traits of Candida spp. and confer passive protection against candidiasis.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: January 10, 2012
    Assignee: Istituto Superiore di Sanita
    Inventors: Antonio Cassone, Flavia de Bernardis, Steven Grant, Haiqun Liu