Patents by Inventor Haitao Wang

Haitao Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10233223
    Abstract: A recombinant fusion protein comprising a human erythropoietin peptide portion linked to an immunoglobulin peptide portion is described. The fusion protein has a prolonged half-life in vivo compared to naturally occurring or recombinant native human erythropoietin. In one embodiment, the protein has a half-life in vivo at least three-fold higher than native human erythropoietin. The fusion protein exhibits enhanced erythropoietic bioactivity compared to native human erythropoietin. In one embodiment, the fusion protein comprises the complete peptide sequence of a human erythropoietin (EPO) molecule and the peptide sequence of an Fc fragment of human IgG1, which Fc fragment includes the hinge region, CH2 and CH3 domains. The EPO molecule may be linked directly to the Fc fragment to avoid extraneous peptide linkers and lessen risk of an immunogenic response when administered. In one embodiment the hinge region is a human Fc fragment variant having a non-cysteine residue at amino acid 6.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: March 19, 2019
    Assignee: Novagen Holding Corporation
    Inventors: Haitao Wang, Yong Du, Rui Zhang, Jing Xu, Longbin Liu
  • Publication number: 20190077843
    Abstract: This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human inteferon like alpha 2b (HuIFN-?2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon, therapy, such as viral diseases and cancer.
    Type: Application
    Filed: April 30, 2018
    Publication date: March 14, 2019
    Inventors: Haitao WANG, Chunsheng MAO, Jizhi LI, Ling WANG, Yong DU, Longbin LIU, Jing XU, Rui ZHANG
  • Publication number: 20190070307
    Abstract: A recombinant fusion protein comprising a human erythropoietin peptide portion linked to an immunoglobulin peptide portion is described. The fusion protein has a prolonged half-life in vivo in comparison to naturally occurring or recombinant native human erythropoietin. In one embodiment of the invention, the protein has a half-life in vivo at least three fold higher than native human erythropoietin. The fusion protein also exhibits enhanced erythropoietic bioactivity in comparison to native human erythropoietin. In one embodiment, the fusion protein comprises the complete peptide sequence of a human erythropoietin (EPO) molecule and the peptide sequence of an Fc fragment of human immunoglobulin IgG1. The Fc fragment in the fusion protein includes the hinge region, CH2 and CH3 domains of human immunoglobulin IgG1. The EPO molecule may be linked directly to the Fc fragment to avoid extraneous peptide linkers and lessen the risk of an immunogenic response when administered in vivo.
    Type: Application
    Filed: May 29, 2018
    Publication date: March 7, 2019
    Inventors: Haitao Wang, Yong Du, Rui Zhang, Jing Xu, Longbin Liu
  • Publication number: 20190036163
    Abstract: A method for preparing a composite solid state electrolyte includes the steps of: 1): dissolving a polyethylene oxide monomer and an additive in an organic solvent, obtaining a polymer after filtering; 2): adding Ru(Cp*)Cl(PPh3)2 to an organic solvent, dissolving the polymer in step 1) and a polystyrene monomer in the organic solvent, and obtaining a PEO-PST two-phase polymer; 3): adding Li2S, P2S5, GeS2, Al2S3, BaS and milling, pressing the milled powder into a wafer, and obtaining an Al, Ba doped solid state electrolyte material LABGPS; and 4): mixing the PEO-PST two-phase polymer in step 2) and the solid state electrolyte material LABGPS in step 3), adding a lithium salt, dissolving and dispersing the mixture in a mixed solution of tetrahydrofuran and acetone to form a sol, drying the sol, transferring the dried sol to a vacuum oven for vacuum drying, and obtaining a final composite solid state electrolyte PEO-PST-LABGPS.
    Type: Application
    Filed: July 25, 2018
    Publication date: January 31, 2019
    Inventors: Xing Yang, Xiaoyan Liu, Haitao Wang
  • Patent number: 10176374
    Abstract: An image processing method includes determining a vertical baseline and a horizontal baseline corresponding to a boundary of an eye of a user in an input image of the eye of the user, and aligning the input image based on the vertical baseline and the horizontal baseline.
    Type: Grant
    Filed: November 25, 2016
    Date of Patent: January 8, 2019
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Kang Xue, Shuzheng Gao, Xiying Wang, Haitao Wang
  • Publication number: 20180366359
    Abstract: A method and apparatus for de-chucking a workpiece is described that uses a swing voltage sequence. One example pertains to a method that includes applying a mechanical force from an electrostatic chuck against the back side of a workpiece that is electrostatically clamped to the chuck, applying a sequence of voltage pulses with a same polarity to the electrodes, each pulse of the sequence having a lower voltage than the preceding pulse, each pulse of the sequence having a lower voltage than the preceding pulse, and determining whether the workpiece is released from the chuck after the sequence of additional voltage pulses and if the workpiece is not released then repeating applying the sequence of voltage pulses.
    Type: Application
    Filed: June 20, 2017
    Publication date: December 20, 2018
    Inventors: Haitao Wang, Wonseok Lee, Sergio Fukuda Shoji, Chunlei Zhang, Kartik Ramaswamy
  • Patent number: 10142616
    Abstract: An eyeglass-less 3D display device, and a device and method that compensate for a displayed margin of error are provided. The display device acquires an image of an integral image display (IID) image captured by a single camera, and compensates for a margin of error which arises due to a discrepancy between the designed position of a micro lens array located on one surface of a 2D panel and the actual position thereof, so as to provide a high-quality 3D image.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: November 27, 2018
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Weiming Li, Mingcai Zhou, Shaohui Jiao, Tao Hong, Xiying Wang, Haitao Wang, Dong Kyung Nam
  • Patent number: 10126562
    Abstract: A method for reducing a moire fringe includes calculating a moire fringe width for each of different angles between a microlens array and pixels of a display screen. The method includes determining, to be a final inclination angle between the microlens array and the pixels of the display screen, one of the different inclination angles that corresponds to a minimum width among the calculated moire fringe widths.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: November 13, 2018
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Jinho Lee, Tao Hong, Weiming Li, DongKyung Nam, Kang Xue, Xiying Wang, Zhihua Liu, Gengyu Ma, Haitao Wang, Mingcai Zhou
  • Publication number: 20180323042
    Abstract: The present disclosure generally relates to methods of and apparatuses for controlling a plasma sheath near a substrate edge. The apparatus includes an auxiliary electrode that may be positioned adjacent an electrostatic chuck. The auxiliary electrode is recursively fed from a power source using equal length and equal impedance feeds. The auxiliary electrode is vertically actuatable, and is tunable with respect to ground or other frequencies responsible for plasma generation. Methods of using the same are also provided.
    Type: Application
    Filed: April 19, 2018
    Publication date: November 8, 2018
    Inventors: Haitao WANG, Anwar HUSAIN, Kartik RAMASWAMY, Jason A. KENNEY, Jeffrey LUDWIG, Chunlei ZHANG, Wonseok LEE
  • Patent number: 10117949
    Abstract: A recombinant fusion protein comprising a human erythropoietin peptide portion linked to an immunoglobulin peptide portion is described. The fusion protein has a prolonged half-life in vivo in comparison to naturally occurring or recombinant native human erythropoietin. In one embodiment of the invention the protein has a half-life in vivo at least three fold higher than native human erythropoietin. The fusion protein also exhibits enhanced erythropoietic bioactivity in comparison to native human erythropoietin. In one embodiment, the fusion protein comprises the complete peptide sequence of a human erythropoietin (EPO) molecule and the peptide sequence of an Fc fragment of human immunoglobulin IgG1. The Fc fragment in the fusion protein includes the hinge region, CH2 and CH3 domains of human immunoglobulin IgG1. The EPO molecule may be linked directly to the Fc fragment to avoid extraneous peptide linkers and lessen the risk of an immunogenic response when administered in vivo.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: November 6, 2018
    Assignee: NOVAGEN HOLDING CORPORATION
    Inventors: Haitao Wang, Yong Du, Rui Zhang, Jing Xu, Longbin Liu
  • Publication number: 20180308736
    Abstract: Embodiments include an electrostatic chuck assembly having an electrostatic chuck mounted on an insulator. The electrostatic chuck and insulator may be within a chamber volume of a process chamber. In an embodiment, a ground shield surrounds the electrostatic chuck and the insulator, and a gap between the ground shield and the electrostatic chuck provides an environment at risk for electric field emission. A dielectric filler can be placed within the gap to reduce a likelihood of electric field emission. The dielectric filler can have a flexible outer surface that covers or attaches to the electrostatic chuck, or an interface between the electrostatic chuck and the insulator Other embodiments are also described and claimed.
    Type: Application
    Filed: April 24, 2017
    Publication date: October 25, 2018
    Inventors: Kartik Ramaswamy, Anwar Husain, Haitao Wang, Evans Yip Lee, Jaeyong Cho, Hamid Noorbakhsh, Kenny L. Doan, Sergio Fukuda Shoji, Chunlei Zhang
  • Patent number: 10096132
    Abstract: A feature point positioning apparatus includes a memory storing computer-executable instructions; and one or more processors configured to execute the computer-executable instructions such that the one or more processors are configured to, iteratively update a first form coefficient based on, a nonlinear feature extracted from an image, and a regression factor matrix obtained through training, and detect a position of the feature point of the image based on, the updated first form coefficient, and a statistical form model obtained through training.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: October 9, 2018
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Mingcai Zhou, Jingu Heo, Tao Hong, Weiming Li, Zairan Wang, Zhihua Liu, Dong Kyung Nam, Haitao Wang
  • Publication number: 20180254171
    Abstract: Methods and apparatus for boosting ion energies are contemplated herein. In one embodiment, the methods and apparatus comprises a controller, a process chamber with a symmetrical plasma source configured to process a wafer, one or more very high frequency (VHF) sources, coupled to the process chamber, to generate plasma density and two or more frequency generators that generate low frequencies relative to the one or more VHF sources, coupled to a bottom electrode of the process chamber, the two or more low frequency generators configured to dissipate energy in the plasma sheath, wherein the controller controls the one or more VHF sources to generate a VHF signal and the two or more low frequency sources to generate two or more low frequency signals.
    Type: Application
    Filed: March 3, 2017
    Publication date: September 6, 2018
    Inventors: WONSEOK LEE, KARTIK RAMASWAMY, Ankur AGARWAL, Haitao WANG
  • Patent number: 10049277
    Abstract: A method and apparatus for tracking an object, and a method and apparatus for calculating object pose information are provided. The method of tracking the object obtains object feature point candidates by using a difference between pixel values of neighboring frames. A template matching process is performed in a predetermined region having the object feature point candidates as the center. Accordingly, it is possible to reduce a processing time needed for the template matching process. The method of tracking the object is robust in terms of sudden changes in lighting and partial occlusion. In addition, it is possible to track the object in real time. In addition, since the pose of the object, the pattern of the object, and the occlusion of the object are determined, detailed information on action patterns of the object can be obtained in real time.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: August 14, 2018
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Jung-bae Kim, Haitao Wang
  • Publication number: 20180210208
    Abstract: Provided is a head-mounted display (HMD) apparatus, including a light modulator and eye lens, where the light modulator is configured to perform integral imaging on an image output from a 2D display panel, to form a light field image, the eye lens are configured to magnify the light field image formed by the light modulator.
    Type: Application
    Filed: January 25, 2018
    Publication date: July 26, 2018
    Applicant: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Mingcai ZHOU, Tao HONG, Weiming LI, Haitao WANG
  • Patent number: 10015479
    Abstract: A three-dimensional (3D) display method includes generating N first visual images, N being a natural number greater than 1; generating M second visual images from each of the N first visual images, M being a natural number greater than 1; acquiring N visual image groups corresponding to the N first visual images, respectively, such that, for each one of the N visual image groups, the visual image group includes the M second visual images generated from the first visual image, from among the N first visual images, to which the visual image group corresponds; generating M elemental image array (EIA) images based on the N visual image groups; and time-share displaying the M EIA images.
    Type: Grant
    Filed: September 1, 2014
    Date of Patent: July 3, 2018
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Mingcai Zhou, Shandong Wang, Shaohui Jiao, Tao Hong, Weiming Li, Haitao Wang, Ji Yeun Kim
  • Patent number: 9982028
    Abstract: This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology in described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon like alpha 2b (HuIFN-?2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer.
    Type: Grant
    Filed: January 11, 2016
    Date of Patent: May 29, 2018
    Assignee: Novagen Holding Corporation
    Inventors: Haitao Wang, Chunsheng Mao, Jizhi Li, Ling Wang, Yong Du, Longbin Liu, Jing Xu, Rui Zhang
  • Patent number: 9977981
    Abstract: Provided are methods and apparatuses for calibrating a three-dimensional (3D) image in a tiled display including a display panel and a plurality of lens arrays. The method includes capturing a plurality of structured light images displayed on the display panel, calibrating a geometric model of the tiled display based on the plurality of structured light images, generating a ray model based on the calibrated geometric model of the tiled display, and rendering an image based on the ray model.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: May 22, 2018
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Weiming Li, Mingcai Zhou, Shandong Wang, Shaohui Jiao, Tao Hong, Haitao Wang, Ji Yeun Kim
  • Publication number: 20180137548
    Abstract: A method for adatptively implementing an eNote is provided. The method comprises: entering the information related to fields on the eNote to be generated; determining the template size of the eNote based on the entered information related to fields by the preconfigured computation function, and generating the template of the eNote, wherein the input of the preconfigured computation function is the entered information related to fields, and the output is the template size of the eNote to be generated; and filling in the information corresponding to each of fields on the generated eNote template, thereby producing the final eNote.
    Type: Application
    Filed: April 22, 2016
    Publication date: May 17, 2018
    Applicant: CHINA UNIONPAY CO., LTD.
    Inventors: Haitao Wang, Yawei Yin, Qi Zhang, Jiaying Lin
  • Publication number: 20180119284
    Abstract: An apparatus includes a powder storage tank (21) and a gas chamber (14), the powder storage tank (21) being provided with an outlet duct (23) in communication with the gas chamber (14). The apparatus further includes a monitoring device (24), a first switch (25) and a second switch (26). The monitoring device (24) is provided between the powder storage tank (21) and the gas chamber (14) while communicating with the outlet duct, and configured to monitor the powder content per unit volume in the outlet duct when the gas path between the monitoring device and the gas chamber is in the close state. The first switch (25) is provided between the monitoring device (24) and the outlet duct (23), and the second switch (26) is provided between the monitoring device (24) and the gas chamber (14). A method of using the apparatus is also provided.
    Type: Application
    Filed: September 13, 2016
    Publication date: May 3, 2018
    Inventors: Haitao WANG, Niu TIAN, Wenyuan SUN, Song GAO