Abstract: The present disclosure provides a display panel, a manufacturing method and a display device. The display panel includes a first substrate, a second substrate and liquid crystal molecules. Each sub-pixel includes n domains, and at least two of the n domains are arranged in a first direction. An alignment film is arranged on one or both of the first substrate and the second substrate and provided with alignment directions, and/or slit electrodes each with a slit are arranged on one or both of the first substrate and the second substrate. The alignment directions in at least two adjacent domains in the n domains are different and/or extension directions of the slits in any two adjacent domains are different, so that the liquid crystal molecules in different domains are provided with different pretilt angles.