Abstract: A method for measuring a concentration of an analyte in a bio-sample using an electrochemical bio-sensor according to an exemplary embodiment of the present invention is characterized by a step of obtaining predetermined features from induced currents obtained by applying a DC voltage according to chronoamperometry in which, after a whole blood sample is injected to the electrochemical bio-sensor, a concentration of an analyte is obtained from an induced current obtained by applying a DC voltage for a certain time and from all induced currents obtained by further applying several step-ladder perturbation potentials for a short time subsequent to the DC voltage for the certain time, and is also characterized by minimization of a measurement error caused by a hindering material by forming a calibration equation by combining the at least one feature in a function and optimizing various conditions of the bio-sample through Deleted Texts multivariable analysis.

Abstract: A releasing structure for a lancing device according to an exemplary embodiment of the present invention may include: a lancet body with a lancet at the front; a lancet holder mounted with the lancet body with the lancet at the front; a stem disposed behind the lancet holder and moving the lancet holder forward/backward; a rotary housing pushing/pulling the stem while turning forward at a predetermined angle about a rotational axis defined in the movement direction of the lancet; a torsion spring storing torque for turning the rotary housing forward at a predetermined angle; and a loading handle transmitting torque to the torsion spring while turning forward at a predetermined angle.

Abstract: The present disclosure relates to a blood sugar meter system with a wireless communication module, and more particularly, to a time synchronization method between a blood sugar meter system with a wireless communication module synchronized with a cellular network such as a global system for mobile communication (GSM)/code division multiple access (CDMA) network and the cellular network. The present invention provides a blood sugar meter system with a wireless communication module applying a time synchronization scheme including: a global system for mobile communication (GSM)/code division multiple access (CDMA) network transmitting network identity and time zone (NITZ) information; and a blood sugar meter metering user's blood sugar data, wherein the blood sugar meter synchronizes a network time according to the NITZ information with an internal time of the metered data and transmits the metered blood sugar data to a server connected to the GSM/CDMA network.

Abstract: The present invention relates to a biochemical analysis cartridge having improved operability. More particularly, the present invention provides a biochemical analysis cartridge including an insertion-type sample cartridge and a reaction cartridge receiving the insertion-type sample cartridge, in which,as the sample cartridge is inserted into the reaction cartridge,a reaction solution chamber moves toward a broken part of a covertape so as to automatically supply the reaction solution stored in the chamber. The biochemical analysis cartridge having improved operability according to the present invention can induce the mixing between a sample and a reaction solution by simply inserting them into the reaction cartridge and a reaction thereafter, thereby minimizing the process of a measurer to intervene in the assay, and subsequently improving user convenience and operability.

Abstract: The present invention relates to a stabilizing composition useful for improving the stability of reagent for redox reaction, and a reagent composition for redox reaction having an improved stability. The reagent composition for redox reaction can be applied for a reagent for electrochemical biosensor.

Abstract: The present invention relates to an electrochemical biosensor with improved hematocrit measurement accuracy for measuring blood glucose. According to the present invention, an electrochemical biosensor including a first electrode part for correcting a measured hematocrit value and a second electrode part for measuring a glucose concentration is effective in improving accuracy of a measured hematocrit value and in more improving accuracy of a measured blood glucose concentration using the measured hematocrit values for correction, because an insulation cover is made thinner than a working electrode and an auxiliary electrode, so that areas of a first working electrode and a first auxiliary electrode of the first electrode part exposed to a blood sample become equal; a distance between the first working electrode and the second working electrode becomes constant; and electrode areas are maintained constantly by the insulation cover even when a positioning error occurs during printing.

Abstract: The present invention relates to a biochemical assay cartridge. More particularly, the present invention provides a biochemical assay cartridge including an insertion-type solution cartridge and a reaction cartridge receiving the insertion-type solution cartridge, in which the solution cartridge is inserted into the reaction cartridge to catch a protruding protection film inducement unit by a latch in the reaction cartridge and thus break the protection film inducement unit and a protection film for sealing a reaction solution storage unit attached to the solution cartridge is automatically detached to discharge the reaction solution from the solution cartridge to the reaction cartridge.

Abstract: A cartridge for an apparatus for analyzing blood chemistry includes an apparatus frame having a compartment; a cartridge that is inserted into the compartment of the apparatus frame and includes a sensor card, a solution valve unit, and a blood introducing unit; a controller that receives a signal generated from the sensor card and processes the signal; a lever for the blood introducing unit connected to the apparatus frame; a power transmitting unit that is provided to the apparatus frame and transmits power of the lever for the blood introducing unit to open/close the blood introducing unit of the cartridge; a solution transporting unit that is provided to the apparatus frame and transports the solutions; and a driving unit that actuates the solution valve unit of the cartridge by the controller and opens or closes the tubing flowing of the solutions.

Abstract: Disclosed herein is a connector for connecting a biosensor and a measuring device thereof. The connector includes an insertion guide to prevent a connection electrode from being damaged due to a mis-insertion of the biosensor when the biosensor is inserted into the connector, and also may further include an integrated photo reflector for emitting and detecting an infrared ray to identify production lot information of the biosensor, so that production information of the biosensor may be simply opened, and as a result, the connector may be used as a connector for connecting the biosensor and the measuring device thereof.

Abstract: Disclosed is a hemolysis reagent composition for the quantitative analysis of glycated hemoglobin (HbAlc) via an enzymatic method. The hemolysis reagent compositions of the present invention containing a zwitterionic surfactant and a nitrous compound considerably accelerate hemolysis rate due to the presence of the zwitterionic surfactant, and also induce the N-terminal ?-chain of hemoglobin released by hemolysis to be exposed to the outside of the hemoglobin molecule and assists the participation of a greater number of molecules in the reaction, thereby improving reaction sensitivity and reaction rate of the glycated hemoglobin, and the nitrous compound makes the protein structure of the hemoglobin flexibly modified so that the amino acid sequence of the N-terminal ?-chain of hemoglobin can be readily cut off, thereby significantly reducing the entire time required for the measurement and improving the accuracy of the measurement.

Abstract: A sensor for measuring a concentration of a specific protein using a biosensor with a measurement speed improved from a conventional impedance measurement. The sensor is capable of efficiently and accurately measuring impedance generated by a selective binding to the protein by Fourier-transforming an electric current signal obtained by applying a potential signal of a delta function waveform. The device for measuring a protein using a biosensor is capable of measuring concentration of the protein with accuracy, measurement time is shortened and the concentration of protein can be accurately measured by removing the influence of dispersion.

Abstract: The present disclosure relates to a blood sugar meter system with a wireless communication module, and more particularly, to a time synchronization method between a blood sugar meter system with a wireless communication module synchronized with a cellular network such as a global system for mobile communication (GSM)/code division multiple access (CDMA) network and the cellular network. The present invention provides a blood sugar meter system with a wireless communication module applying a time synchronization scheme including: a global system for mobile communication (GSM)/code division multiple access (CDMA) network transmitting network identity and time zone (NITZ) information; and a blood sugar meter metering user's blood sugar data, wherein the blood sugar meter synchronizes a network time according to the NITZ information with an internal time of the metered data and transmits the metered blood sugar data to a server connected to the GSM/CDMA network.

Abstract: Provided are an amperometric sensor and device for electrochemically quantifying nitrosothiol (RSNO), which is associated with storage and delivery of nitric oxide (NO) in the human body. The amperometric sensor for measuring a concentration of RSNO includes an electrode configured to measure an electric current generated by an oxidation reaction of NO, and a means configured to start and stop photo-induced decomposition of RSNO. Here, the electric current is measured by the oxidation reaction of NO before and after the photo-induced decomposition of RSNO. The amperometric sensor may measure separate signals of RSNO and NO, which are present in the sample at the same time, using one electrode, thereby preventing an inhibition action caused by NO during the measurement of RSNO. Also, the amperometric sensor is simple in structure and easy to manufacture and may be applied to manufacture of a small electrode, and thus may be developed as a sensor for in vivo measurements.

Abstract: The present invention relates to a lancet device that can solve the problem of falling or losing a cover when mounting or separating a lancet and reduce the pain that accompanies blood-taking. A lancet device according to an exemplary embodiment of the present invention includes: a lancet holder having a lancet seat to mount a lancet at one end; an operating mechanism disposed at the other end of the lancet holder and loading and releasing the lancet holder along a predetermined path; and an a housing receiving the operating mechanism and having one end coupled to the lancet holder, and further includes a cover that covers the housing so that the lancet holder is received in the housing, is at least partially connected with the housing in order not to separate from the housing in use, and has protrusions on the front part.

Abstract: A releasing structure for a lancing device according to an exemplary embodiment of the present invention may include: a lancet body with a lancet at the front; a lancet holder mounted with the lancet body with the lancet at the front; a stem disposed behind the lancet holder and moving the lancet holder forward/backward; a rotary housing pushing/pulling the stem while turning forward at a predetermined angle about a rotational axis defined in the movement direction of the lancet; a torsion spring storing torque for turning the rotary housing forward at a predetermined angle; and a loading handle transmitting torque to the torsion spring while turning forward at a predetermined angle.

Abstract: The present invention provides a lancet holder that can smoothly and accurately hold all of lancets with different cross-sections and diameters and can keep them vertical, and a lancet device including the lancet holder. To this end, a lancet holder according to an exemplary embodiment of the present invention includes a holder body having a lancet seat at one end to mount a lancet and receiving the lancet and elastic fixing portions arranged in pairs to face each other on the inner side of the holder body so that the lancet received in the holder body is vertically held, and elastically fixing the lancet.

Abstract: A lancet-separable lancet device according to an exemplary embodiment of the present invention includes: a lancet holder having a lancet seat to mount a lancet at one end and a separation hole at the other end; an operating mechanism disposed at the other end of the lancet holder so that the lancet holder is loaded and released by traveling along a predetermined path; a housing receiving the operating mechanism and having one end coupled to the lancet holder; an operation switch connected to the operating mechanism and operating the operating mechanism by pressing it; a cover covering one end of the housing and having a through-hole at the center through which a lancet needle of the lancet instantaneously protrudes; and a lancet separation mechanism disposed at the other side of the lancet holder and separating the lancet from the lancet holder by being inserted into the separation hole of the lancet holder.

Abstract: A lancet device with an adjustable hypodermic penetration depth according to an exemplary embodiment of the present invention includes: a lancet holder having a lancet seat to mount a lancet at one end; an operating mechanism disposed at the other end of the lancet holder and loading and releasing the lancet holder along a predetermined path; a depth adjusting member receiving the lancet holder and having at least two grooves formed at a predetermined angle on the circumferential surface of one end to form inclined passages clockwise or counterclockwise; and a housing receiving the lancet holder and the operating mechanism and having a protrusion that is formed on the inner side of an end and fitted step by step in the grooves when the depth adjusting member turns at a predetermined angle.

Abstract: The present invention provides a solution bag that is used for medical treatment and stores solution used for an apparatus for analyzing blood chemistry that measures and analyzes the concentrations of electrolytes, the partial pressures of gases, and the concentrations of metabolites or the volume ratio of red blood cells contained in blood. The solution bag for an apparatus for analyzing blood chemistry of the present invention includes: a receptacle that contains a solution; a valve body that is attached to the receptacle and has a through-hole longitudinally formed therein; a valve spool that is disposed in the through-hole of the valve body; and a solution leakage preventing unit that is disposed in the valve spool, in which the valve body has a flow channel and a solution discharging pipe spaced at a predetermined distance from each other.

Abstract: A composition of redox-reagent containing metal-containing complex and thionine or its derivative as electron transfer mediator for use in an electrochemical biosensor, and a biosensor containing the same are provided. With the increase in reaction rate between redox enzyme-thionine (or its derivative)-metal-containing complex in the composition of redox-reagent containing metal-containing complex and thionine or its derivative, glucose detection efficiency markedly increases, and the composition is hardly influenced from high humidity and interfering substances. Accordingly, the composition of redox-reagent is useful in fabricating an electrochemical biosensor for detecting glucose in blood.