Patents by Inventor Hana CERNECKA
Hana CERNECKA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230112499Abstract: The present invention covers furoindazole compounds of general formula (I): in which (I) are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of autoimmune diseases such as multiple sclerosis, psoriasis, psoriatic arthritis, rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus, primary and secondary autoimmune uveitis, inflammatory disorders like endometriosis, inflammatory eye diseases, inflammatory kidney diseases, inflammatory liver diseases like non-alcoholic, alcoholic- and toxic fatty liver diseases, lung diseases like asthma, idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease and metabolic and metabolic-endocrine disorders like metabolic syndrome, insulin resistance, diabetes mellitus type I and type II, and poType: ApplicationFiled: December 14, 2020Publication date: April 13, 2023Applicant: Bayer AktiengesellschaftInventors: Olaf PANKNIN, Frank SACHER, Nicole SCHMIDT, Gernot LANGER, Katrin NOWAK-REPPEL, Reinhard NUBBEMEYER, Sabine PILARI, Antje ROTTMANN, Hideki MIYATAKE ONDOZABAL, Holger SIEBENEICHER, Antonius TER LAAK, Hana CERNECKA
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Patent number: 11298367Abstract: The present invention relates to prodrugs of 3-({3-(4-chlorophenyl)-5-oxo-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl ]-4,5-dihydro-1H-1,2,4-triazol-1-yl}methyl)-1-[3-(trifluoromethyl)-pyridin-2-yl ]-1H-1,2,4-triazole-5-carboxamide, 3-({3-(4-chlorophenyl)-5-oxo-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl ]-4,5-dihydro-1H-1,2,4-triazol-1-yl}methyl)-1-[2-(trifluoromethyl)-phenyl]-1H-1,2,4-triazole-5-carboxamide and 3-({3-(4-chlorophenyl)-5-oxo-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl ]-4,5-dihydro-1H-1,2,4-triazol-1-yl}methyl)-1-(3-chloropyridin-2-yl)-1H-1,2,4-triazole-5-carboxamide, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.Type: GrantFiled: October 17, 2018Date of Patent: April 12, 2022Assignee: Bayer AktiengesellschaftInventors: Marie-Pierre Collin-Kroepelin, Peter Kolkhof, Thomas Neubauer, Chantal Fuerstner, Elisabeth Pook, Matthias Beat Wittwer, Carsten Schmeck, Pierre Wasnaire, Heiko Schirmer, Hana Cernecka, Karoline Droebner, Hanna Tinel, Anja Buchmueller, Thomas Mondritzki, Axel Kretschmer, Klemens Lustig, Robert Fricke, Guillaume Levilain, Ursula Krenz, Norbert Witowski
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Patent number: 11091463Abstract: The present invention relates to novel 5-(carboxamide)-1-pyridinyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.Type: GrantFiled: September 23, 2019Date of Patent: August 17, 2021Assignee: Bayer Pharma AktiengesellschaftInventors: Marie-Pierre Collin, Peter Kolkhof, Thomas Neubauer, Chantal Fuerstner, Elisabeth Pook, Matthias Beat Wittwer, Klemens Lustig, Anja Buchmueller, Hanna Tinel, Karoline Droebner, Thomas Mondritzki, Heiko Schirmer, Axel Kretschmer, Carsten Schmeck, Pierre Wasnaire, Hana Cernecka
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Publication number: 20200338096Abstract: The present invention relates to prodrugs of 3-({3-(4-chlorophenyl)-5-oxo-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-4,5-dihydro-1H-1,2,4-triazol-1-yl}methyl)-1-[3-(trifluoromethyl)-pyridin-2-yl]-1H-1,2,4-triazole-5-carboxamide, 3-({3-(4-chlorophenyl)-5-oxo-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-4,5-dihydro-1H-1,2,4-triazol-1-yl}methyl)-1-[2-(trifluoromethyl)-phenyl]-1H-1,2,4-triazole-5-carboxamide and 3-({3-(4-chlorophenyl)-5-oxo-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-4,5-dihydro-1H-1,2,4-triazol-1-yl}methyl)-1-(3-chloropyridin-2-yl)-1H-1,2,4-triazole-5-carboxamide, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.Type: ApplicationFiled: October 17, 2018Publication date: October 29, 2020Inventors: Marie-Pierre COLLIN-KROEPELIN, Peter KOLKHOF, Thomas NEUBAUER, Chantal FUERSTNER, Elisabeth POOK, Matthias Beat WITTWER, Carsten SCHMECK, Pierre WASNAIRE, Heiko SCHIRMER, Hana CERNECKA, Karoline DROEBNER, Hanna TINEL, Anja BUCHMUELLER, Thomas MONDRITZKI, Axel KRETSCHMER, Klemens LUSTIG, Robert FRICKE, Guillaume LEVILAIN, Ursula KRENZ, Norbert WITOWSKI
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Patent number: 10815205Abstract: The present invention relates to novel 5-(carboxamide)-1-phenyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.Type: GrantFiled: May 2, 2017Date of Patent: October 27, 2020Assignee: BAYER PHARMA AKTIENGESELLSCHAFTInventors: Marie-Pierre Collin-Kröpelin, Peter Kolkhof, Thomas Neubauer, Chantal Fürstner, Elisabeth Pook, Matthias Beat Wittwer, Klemens Lustig, Anja Buchmüller, Hanna Tinel, Karoline Dröbner, Thomas Mondritzki, Heiko Schirmer, Axel Kretschmer, Carsten Schmeck, Pierre Wasnaire, Hana Cernecka
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Publication number: 20200017473Abstract: The present invention relates to novel 5-(carboxamide)-1-pyridinyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.Type: ApplicationFiled: September 23, 2019Publication date: January 16, 2020Inventors: Marie-Pierre COLLIN, Peter KOLKHOF, Thomas NEUBAUER, Chantal FUERSTNER, Elisabeth POOK, Matthias Beat WITTWER, Klemens LUSTIG, Anja BUCHMUELLER, Hanna TINEL, Karoline DROEBNER, Thomas MONDRITZKI, Heiko SCHIRMER, Axel KRETSCHMER, Carsten SCHMECK, Pierre WASNAIRE, Hana CERNECKA
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Patent number: 10472348Abstract: The present invention relates to novel 5-(carboxamide)-1-pyridinyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.Type: GrantFiled: May 2, 2018Date of Patent: November 12, 2019Assignee: BAYER PHARMA AKTIENGESELLSCHAFTInventors: Marie-Pierre Collin, Peter Kolkhof, Thomas Neubauer, Chantal Fürstner, Elisabeth Pook, Matthias Beat Wittwer, Klemens Lustig, Anja Buchmüller, Hanna Tinel, Karoline Dröbner, Thomas Mondritzki, Heiko Schirmer, Axel Kretschmer, Carsten Schmeck, Pierre Wasnaire, Hana Cernecka
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Publication number: 20190161454Abstract: The present invention relates to novel 5-(carboxamide)-1-phenyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.Type: ApplicationFiled: May 2, 2017Publication date: May 30, 2019Inventors: Marie-Pierre COLLIN-KRÖPELIN, Peter KOLKHOF, Thomas NEUBAUER, Chantal FÜRSTNER, Elisabeth POOK, Matthias Beat WITTWER, Klemens LUSTIG, Anja BUCHMÜLLER, Hanna TINEL, Karoline DRÖBNER, Thomas MONDRITZKI, Heiko SCHIRMER, Axel KRETSCHMER, Carsten SCHMECK, Pierre WASNAIRE, Hana CERNECKA
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Publication number: 20190144423Abstract: The present invention relates to novel 5-(carboxamide)-1-pyridinyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.Type: ApplicationFiled: May 2, 2017Publication date: May 16, 2019Inventors: Marie-Pierre COLLIN-KRÖPELIN, Peter KOLKHOF, Thomas NEUBAUER, Chantal FÜRSTNER, Elisabeth POOK, Matthias Beat WITTWER, Klemens LUSTIG, Anja BUCHMÜLLER, Hanna TINEL, Karoline DRÖBNER, Thomas MONDRITZKI, Heiko SCHIRMER, Axel KRETSCHMER, Carsten SCHMECK, Pierre WASNAIRE, Hana CERNECKA
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Publication number: 20190119251Abstract: The present invention relates to novel 5-(carboxamide)-1-aryl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.Type: ApplicationFiled: May 2, 2017Publication date: April 25, 2019Inventors: Marie-Pierre COLLIN-KRÖPELIN, Peter KOLKHOF, Thomas NEUBAUER, Chantal FÜRSTNER, Elisabeth POOK, Matthias Beat WITTWER, Klemens LUSTIG, Anja BUCHMÜLLER, Hanna TINEL, Karoline DRÖBNER, Thomas MONDRITZKI, Heiko SCHIRMER, Carsten SCHMECK, Pierre WASNAIRE, Hana CERNECKA, Axel KRETSCHMER
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Publication number: 20180251447Abstract: The present invention relates to novel 5-(carboxamide)-1-pyridinyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.Type: ApplicationFiled: May 2, 2018Publication date: September 6, 2018Inventors: Marie-Pierre COLLIN, Peter KOLKHOF, Thomas NEUBAUER, Chantal FÜRSTNER, Elisabeth POOK, Matthias Beat WITTWER, Klemens LUSTIG, Anja BUCHMÜLLER, Hanna TINEL, Karoline DRÖBNER, Thomas MONDRITZKI, Heiko SCHIRMER, Axel KRETSCHMER, Carsten SCHMECK, Pierre WASNAIRE, Hana CERNECKA
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Patent number: 9988367Abstract: The present invention relates to novel 5-(carboxamide)-1-pyridinyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.Type: GrantFiled: April 28, 2017Date of Patent: June 5, 2018Assignee: BAYER PHARMA AKTIENGESELLSCHAFTInventors: Marie-Pierre Collin, Peter Kolkhof, Thomas Neubauer, Chantal Fürstner, Elisabeth Pook, Matthias Beat Wittwer, Klemens Lustig, Anja Buchmüller, Hanna Tinel, Karoline Dröbner, Thomas Mondritzki, Heiko Schirmer, Axel Kretschmer, Carsten Schmeck, Pierre Wasnaire, Hana Cernecka
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Publication number: 20170320854Abstract: The present invention relates to novel 5-(carboxamide)-1-pyridinyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of renal and cardiovascular diseases.Type: ApplicationFiled: April 28, 2017Publication date: November 9, 2017Inventors: Marie-Pierre COLLIN, Peter KOLKHOF, Thomas NEUBAUER, Chantal FÜRSTNER, Elisabeth POOK, Matthias Beat WITTWER, Klemens LUSTIG, Anja BUCHMÜLLER, Hanna TINEL, Karoline DRÖBNER, Thomas MONDRITZKI, Heiko SCHIRMER, Axel KRETSCHMER, Carsten SCHMECK, Pierre WASNAIRE, Hana CERNECKA