Patents by Inventor Hans-Henrik Kristensen Hoegenhaug

Hans-Henrik Kristensen Hoegenhaug has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160158317
    Abstract: The present invention relates to variants of a parent antimicrobial peptide. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: February 13, 2016
    Publication date: June 9, 2016
    Applicant: Adenium Biotech A/S
    Inventors: Hans-Henrik Kristensen Hoegenhaug, Per Holse Mygind, Thomas Kruse, Dorotea Raventos Segura, Dorthe Hoj Sandvang, Soren Neve
  • Publication number: 20150031601
    Abstract: The present invention relates to variants of a parent antimicrobial peptide. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: August 11, 2014
    Publication date: January 29, 2015
    Applicant: ADDENIUM BIOTECH APS
    Inventors: Hans-Henrik Kristensen Hoegenhaug, Per Holse Mygind, Thomas Kruse, Dorotea Raventos Segura, Dorthe Hoj Sandvang, Soren Neve
  • Patent number: 8835604
    Abstract: The present invention relates to variants of a parent antimicrobial peptide. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: September 16, 2014
    Assignee: Adenium Biotech Aos
    Inventors: Hans-Henrik Kristensen Hoegenhaug, Per Holse Mygind, Thomas Kruse, Dorotea Raventos Segura, Dorthe Hoj Sandvang, Soren Neve
  • Patent number: 8653024
    Abstract: Provided is treatment of urinary tract infections including bladder infections caused by uropathogenic bacterial strains such as for example Escherichia coli with a beta-hairpin antimicrobial Arenicin polypeptide derived from the murine polychaeta Arenicola marina. Also provided are variants of Arenicin for treatment of urinary tract infections.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: February 18, 2014
    Assignee: Adenium Biotech Aps
    Inventors: Birgitte Thue Ravn, Karoline Sidelmann Brinch, Dorthe Hoej Sandvang, Hans-Henrik Kristensen Hoegenhaug, Dorotea Raventos Segura, Soeren Neve
  • Publication number: 20110306750
    Abstract: The present invention relates to variants of a parent antimicrobial peptide. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: June 2, 2011
    Publication date: December 15, 2011
    Applicant: Novozymes A/S
    Inventors: Hans-Henrik Kristensen Hoegenhaug, Per Holse Mygind, Thomas Kruse, Dorotea Raventos Segura, Dorthe Hoj Sandvang, Soren Neve
  • Patent number: 7935501
    Abstract: The invention relates to the use of co-expression of an antimicrobial agent and an enzyme, with a view to improving yield and/or overall production economy. Examples of antimicrobial agents are antimicrobial peptides such as lactoferricins and antimicrobial enzymes such as lysozyme and glucose oxidase, and examples of enzymes are endoglucanase, xylanase, phytase, protease, galactanase, mannanase, dextranase, alpha-galactosidase, pectate lyase, alpha-amylase and glucoamylase. A fusion product comprising the antimicrobial agent and the enzyme and a cleavable linker is novel, and can be used in animal feed and animal feed additives. The invention also describes the use of a protection domain wherein at least 50% of the amino acid residues comprised in the peptide protection domain are D (Asp) and/or E (Glu). The protection or quenching domain serves to temporarily and reversibly inactivate the antimicrobial peptide during the expression.
    Type: Grant
    Filed: September 13, 2004
    Date of Patent: May 3, 2011
    Assignee: Novozymes Pharma Biotec A/S
    Inventors: Ejner Bech Jensen, Hans-Henrik Kristensen Høgenhaug, Peter Kamp Hansen, Poul Erik Pedersen, Per Holse Mygind
  • Patent number: 7829524
    Abstract: The present invention relates to polypeptides having antimicrobial activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: June 10, 2004
    Date of Patent: November 9, 2010
    Assignee: Novozymes Adenium Biotech A/S
    Inventors: Dorotea Raventos Segura, Per Holse Mygind, Hans-Henrik Kristensen Hoegenhaug, Alessandro Tossi
  • Publication number: 20100120690
    Abstract: The present invention relates to isolated polypeptides having antimicrobial activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: January 14, 2010
    Publication date: May 13, 2010
    Applicant: Novozymes Adenium Biotech A/S
    Inventors: Jesper Vind, Dorotea Raventos Segura, Hans-Henrik Kristensen Hoegenhaug, Per Hose Mygind, Olivier Taboureau
  • Publication number: 20100104552
    Abstract: The present invention relates to antibiotic synergism of pharmaceutical compositions comprising a defensin and a beta-lactam antibiotic.
    Type: Application
    Filed: October 23, 2009
    Publication date: April 29, 2010
    Applicant: Novozymes A/S
    Inventors: Per Holse Mygind, Dorthe Sandvang, Hans-Henrik Kristensen Hoegenhaug, Thomas Kruse, Line Anker Nielsen
  • Publication number: 20100093633
    Abstract: The present invention relates to isolated polypeptides having antimicrobial activity. The invention also relates to polynucleotides encoding the polypeptides; and nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: October 8, 2009
    Publication date: April 15, 2010
    Applicant: Novozymes A/S
    Inventors: Leonardo De Maria, Hans-Henrik Kristensen Hoegenhaug, Dorthe Sandvang
  • Patent number: 7671175
    Abstract: The present invention relates to isolated polypeptides having antimicrobial activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: June 5, 2006
    Date of Patent: March 2, 2010
    Assignee: Novozymes Adenium Biotech A/S
    Inventors: Jesper Vind, Dorotea Raventos Segura, Hans-Henrik Kristensen Hoegenhaug, Per Holse Mygind, Olivier Taboureau
  • Publication number: 20090239757
    Abstract: The present invention relates to a method of identifying control sequences responding to antimicrobial peptides (AMPs), to host cells expressing an AMP and comprising a control sequence of the invention operable linked to a reporter, and to a method of screening for novel AMPs or AMP-variants having improved antimicrobial activity. Particularly the present invention relates to DNA control sequences, wherein the transcriptional profiles of said control sequences are regulated by the presence of an antimicrobial polypeptide expressed inside the host cell.
    Type: Application
    Filed: December 20, 2005
    Publication date: September 24, 2009
    Applicant: Novozymes A/S
    Inventors: Jesper Duus Nielsen, Allan Kent Nielsen, Bjarke Christensen, Poul Erik Pedersen, Hans-Henrik Kristensen Hoegenhaug
  • Publication number: 20080213430
    Abstract: The present invention relates to polypeptides having antimicrobial activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: June 10, 2004
    Publication date: September 4, 2008
    Applicants: Novozymes A/S, Universita' Degli Studi Di Trieste Dipartimento di Biochimica
    Inventors: Dorotea Raventos Segura, Per Holse Mygind, Hans-Henrik Kristensen Hoegenhaug, Alessandro Tossi