Abstract: The present invention relates to a combination therapy of an antibody specifically binding to Angiopoietin 2 (ANG-2), and an antibody specifically binding to VEGF with an antibody specifically binding to programmed death ligand 1 (PD-L1).

Abstract: In order to connect an angle measuring device to a brushless direct-current motor, a coupling is used, the coupling halves (10, 28) of which are each attached to the rotor (46) of the motor and/or the rotor (42) of the angle measuring device. Instead of using a coupling that is rotationally symmetrical at arbitrary angular positions as in the prior art, a coupling is used in which the coupling halves (10, 28) can be connected to one another only in a finite number of relative angular positions. An adjustment must be made before the coupling halves (10, 28) are attached to the respective rotors (46, 52). This allows all subsequent adjustment to be omitted, for example, even for maintenance work.

Abstract: The production costs of electrical machines are to be reduced. To this end, it should be possible to use standard transmitters for different axis heights of the electrical machine. The invention therefore provides a transmitter cover for an electrical machine, having a pot-like hood (11) for mounting on the electrical machine and for covering a transmitter, wherein the hood (11) has a central axis. The transmitter cover also has a mounting ring (10) which engages on the hood (11) in an interlocking manner. As a result, the hood (11) is pressed against the electrical machine in the axial direction when the mounting ring (10) is fixed to the electrical machine. This can prevent fastening screws (13) colliding with other fastening screws on the motor, this possibly being the case when only the hood (11) is used to cover the transmitter.

Abstract: Tumors are identified as responsive to treatment with anti-HER2 antibodies by detecting the presence of a HER2/HER3 and/or HER2/HER1 protein complex or for HER2 phosphorylation in a sample of tumor cells. Patients suffering from a tumor comprising HER/2/HER1 and/or HER2/HER3 heterodimers and/or HER2 phosphorylation are treated with anti-HER2 antibodies, such as rhuMAb 2C4.

Abstract: The production costs of electrical machines are to be reduced. To this end, it should be possible to use standard transmitters for different axis heights of the electrical machine. The invention therefore provides a transmitter cover for an electrical machine, having a pot-like hood (11) for mounting on the electrical machine and for covering a transmitter, wherein the hood (11) has a central axis. The transmitter cover also has a mounting ring (10) which engages on the hood (11) in an interlocking manner. As a result, the hood (11) is pressed against the electrical machine in the axial direction when the mounting ring (10) is fixed to the electrical machine. This can prevent fastening screws (13) colliding with other fastening screws on the motor, this possibly being the case when only the hood (11) is used to cover the transmitter.

Abstract: The invention relates to a cylindrical catalyst body 1 which is characterized in that indentations are provided on the circumferential surface 3 of the catalyst body 1. These indentations are preferably configured as grooves 4 and webs 5 which run parallel to the longitudinal axis 2 of the catalyst body 1.

Abstract: In order to connect an angle measuring device to a brushless direct-current motor, a coupling is used, the coupling halves (10, 28) of which are each attached to the rotor (46) of the motor and/or the rotor (42) of the angle measuring device. Instead of using a coupling that is rotationally symmetrical at arbitrary angular positions as in the prior art, a coupling is used in which the coupling halves (10, 28) can be connected to one another only in a finite number of relative angular positions. An adjustment must be made before the coupling halves (10, 28) are attached to the respective rotors (46, 52). This allows all subsequent adjustment to be omitted, for example, even for maintenance work.

Abstract: The invention relates to a rotor (10) for an electric motor, wherein at least two permanent magnets (18 and 18?) are arranged behind each other in the axial direction (with respect to an axis of rotation (16) of the rotor (10)), instead of a single continuous permanent magnet. Said permanent magnets are separated from each other by an electrically non-conductive separator (20). Thus eddy current losses are reduced and heating of the permanent magnets, caused by the eddy current losses, is greatly prevented. The separator (20) contributes also to increased positioning accuracy of the permanent magnets.

Abstract: The invention relates to a method for cleaning crude terephthalic acid by means of catalytic, hydrogenating aftertreatment using a catalyst material containing at least one hydrogenation metal applied to a carbon carrier consisting of carbon fibres. The invention also relates to a catalyst consisting of the at least one catalyst material containing the at least one hydrogenation metal applied to the carbon fibres, the BET surface of the carbon carrier being <500 m2/g, and a monolithic catalyst consisting of said at least one catalyst material containing the at least one hydrogenation material applied to the carbon fibres, and at least one support element or skeleton element which differs from the catalyst material and is connected to the same, said element mechanically supporting the catalyst material and maintaining the same in a monolithic form.

Abstract: The invention concerns a seatback for a vehicle seat, having an integrated protective device. The protective device includes a device that generates a torque acting in a pivoting direction on an upper back part, a rear-end impact detector that is in effective connection with the torque-generating device in such a way that the device is activated in the event of the rear-end impact and the pivoting motion is initiated, and an immobilization device for retention of the upper back part in the normal use position.

Abstract: A seat back for an automotive seat with an integrated protective device and a process for preventing injuries to a seat occupant caused by an accident in the event of a rear-end impact. The seat back features a bottom seat-back part and a top seat-back part that, by means of a torque, pivots around an axis in the seat back that is perpendicular to the longitudinal axis of the vehicle, out of a position of standard use and into a safety position. To improve the efficiency of such a seat back, it is proposed that the protective device features a device that generates the torque regardless whether the automotive seat is occupied, and means for detecting a rear-end impact, which are actively linked with the torque-generating device in such a way that the device is activated in the event of a rear-end impact and the swinging movement is started.

Abstract: Unsaturated compounds in hydrocarbon streams are hydrogenated over a catalyst which, in the unused state, shows reflections which correspond to the following lattice plane spacings in the X-ray diffraction pattern [in 10−10m]: 4.52, 2.85, 2.73, 2.44, 2.31, 2.26, 2.02, 1.91, 1.80, 1.54, 1.51, 1.49, 1.45 and 1.39 and have specific relative intensities.

Abstract: Aqueous solutions or aqueous emulsions of copolymers are obtainable by copolymerization of (a) from 20 to 95 mol % of at least one monoethylenically unsaturated C4-C12-dicarboxylic acid or the anhydride thereof with (b) from 5 to 80 mol % of at least one branched oligomer or polymer which has a vinyl, vinylidene or alkylvinylene terminal group and is of at least 9 carbon atoms and (c) from 0 to 50 mol % of at least one further monoethylenically unsaturated compound which is copolymerizable with the monomers (a) and (b) and contain from 0.5 to 70% by weight, based on the total amount of the solutions or emulsions, of these copolymers. These copolymer solutions or emulsions are suitable as leather assistants and as dispersants for pigments.

Abstract: A catalyst packing which can be produced by vapor deposition and/or sputtering of at least one substance active as catalyst and/or promotor onto woven or knitted fabrics or sheets as support material is used in a process for catalytic distillation in which a heterogeneously catalyzed reaction is combined with a simultaneous distillation or rectification over the catalyst packing.

Abstract: A non-aqueous rinsing medium is disclosed, and a process for using same as a rinsing agent in a process for spray-coating of mass-produced substrates (such as automobile bodies) with frequent changes between at least one aqueous and at least one non-aqueous coating agent inside a spray-coating chamber, wherein with at least each change of coating agent the installations to be rinsed are rinsed automatically with the non-aqueous rinsing medium consisting of (a) 20 to 35% by weight of one or more N-alkyl pyrrolidones, (b) 20 to 35% by weight of butyl acetate and/or isobutyl acetate, (c) 10 to 20% by weight of one or more glycol ethers, which are water-miscible without miscibility gap, (d) 5 to 15% by weight of ethanol, propanol and/or isopropanol, (e) 10 to 20% by weight of one or more aliphatic C4-C7-ketones, (f) 0 to 5% by weight of one or more organic solvents conventionally used in coating agents, and (g) 0 to 5% by weight of one or more auxiliary agents, whereby components (a), (c) and (d) comprise

Abstract: A process for preparing a compound of the formula I where R1 and R2 are hydrogen or C1-C4-alkyl and R3 is C1-C10-alkyl, phenyl or C1-C4-alkyl-substituted phenyl, comprises reacting a compound II with a compound of the formula III where X is chlorine, bromine or iodine, in the presence of a Friedel-Crafts catalyst in one step to give a compound I.

Abstract: Copolymer comprising ethylene units and vinyl formate units, the content of free vinyl formate in the polymer preferably being not more than 5000 ppm, based on the weight of the copolymer, a process for its preparation, and its use as flow improver, especially in petroleum distillates, preferably fuel and propellant compositions, especially petroleum middle distillates, and also a fuel and propellant composition comprising a principal quantity of a fuel and propellant and that quantity of a copolymer as above which is effective in improving the flow properties.

Abstract: Fuel and lubricant compositions contain a poly-1-n-alkenylamine as an additive.

Abstract: A process for the preparation of a supported catalyst for the polymerization of .alpha.-olefins, in which(1) a silicon dioxide-containing support gel is prepared by(1.1) introducing a sodium water glass or potassium water glass solution into a swirling stream of an aqueous mineral acid longitudinally and tangentially to the stream, spraying the resultant silica hydrosol in drop form into a gaseous medium and allowing it to solidify to form a hydrogel, and freeing the resultant hydrogel from salts by washing without prior ageing,(1.2) drying the hydrogel resulting from (1.1) to form the support gel,(2) the support gel (1) is charged with chromium trioxide or a chromium compound which can be converted into chromium trioxide under the conditions of process step (3), giving a chromium-containing support gel, and(3) the chromium-containing support gel (2) is heated at from 400.degree. to 1100.degree. C.

Abstract: A novel Phillips catalyst for the copolymerization of ethylene with .alpha.-olefins, contains, as a catalytically active component, a finely divided, aluminum silicate-supported, phosphorus-containing chromium catalyst. This can be prepared by applying at least one organic phosphorus(III), (IV) and/or (V) compound and at least one chromium(III) compound which does not react with said phosphorus compounds under the reaction conditions used, in succcession in any order or simultaneously, to a finely divided aluminum silicate hydrogel or xerogel with formation of a catalyst intermediate and activating the catalyst intermediate at elevated temperatures in an oxidizing atmosphere, with the result that the chromium catalyst is formed. The novel Phillips catalyst gives ethylene/.alpha.-olefin copolymers in which the comonomers are more uniformly distributed over the copolymer chains than is the case with ethylene/.alpha.-olefin copolymers which have been prepared with the aid of conventional Phillips catalysts.