Patents by Inventor Hans Jochen Lang

Hans Jochen Lang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 8,8a-dihydro-3ah-indeno[1,2-d]thiazoles, processes for their preparation and their use as medicaments
    Patent number: 6410577
    Abstract: The invention relates to substituted 8,8a-dihydro-3aH-indeno[1,2-d]thiazoles and to their physiologically acceptable salts and physiologically functional derivatives. Compounds of formula I, in which the radicals are as defined above, and their physiologically acceptable salts and processes for their preparation are described. The compounds are suitable, for example, as anorectics.
    Type: Grant
    Filed: February 23, 2001
    Date of Patent: June 25, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Gerhard Jaehne, Hans-Jochen Lang, Matthias Gossel, Martin Bickel
  • Sulfonamide-substituted fused 7-membered ring compounds, their use as a medicament, and pharmaceutical preparations comprising them
    Publication number: 20020072514
    Abstract: The present invention relates to compounds of formula I, 1
    Type: Application
    Filed: October 25, 2001
    Publication date: June 13, 2002
    Applicant: Hoechst Aktiengesellschaft
    Inventors: Joachim Brendel, Hans Jochen Lang, Uwe Gerlach
  • Substituted cinnamic, acid guanidides, process for their preparation, their use as a medicament, and medicament comprising them
    Patent number: 6399824
    Abstract: Substituted cinnamic acid guanidides, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them. Compounds of the formula I which may be obtained by reaction of a compound II with guanidine.
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: June 4, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Armin Hofmeister, Max Hropot, Uwe Heinelt, Markus Bleich, Hans-Jochen Lang
  • SUBSTITUTED CINNAMIC, ACID GUANIDIDES, PROCESS FOR THEIR PREPARATION, THEIR USE AS A MEDICAMENT, AND MEDICAMENT COMPRISING THEM
    Publication number: 20020058710
    Abstract: Substituted cinnamic acid guanidides, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them.
    Type: Application
    Filed: September 18, 2001
    Publication date: May 16, 2002
    Applicant: Aventis Pharma Deutschland GmbH.
    Inventors: Armin, Hofmeister, Max Hropot, Uwe Heinelt, Markus Bleich, Hans-Jochen Lang
  • Polycyclic dihydrothiazoles having substituted alkyl radicals in the two-position, process for their preparation, and their use as pharmaceuticals
    Patent number: 6387935
    Abstract: The invention relates to polycyclic dihydrothiazoles, and to their physiologically acceptable salts and physiologically functional derivatives. The compounds are according to formula I: in which the radicals have the meanings indicated, and their physiologically acceptable salts and process for their preparation are described. The compounds are suitable, for example, for use as anorectics.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: May 14, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Gerhard Jaehne, Matthias Gossel, Hans-Jochen Lang, Martin Bickel
  • Use of inhibitors of the KQT1 channel and methods of controlling and treating diseases caused by helminths and ectoparasites
    Publication number: 20020055537
    Abstract: Use of inhibitors of the KQT1 channel for preparing a medicament for treating diseases caused by helminths and ectoparasites
    Type: Application
    Filed: November 16, 2001
    Publication date: May 9, 2002
    Applicant: Aventis Pharma Deutschland GMBH
    Inventors: Uwe Gerlach, Joachim Hofmann, Hans Jochen Lang, Aguan Wei
  • Five-membered heterocycles having biphenylsulfonyl substitution, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them
    Publication number: 20020045761
    Abstract: Five-membered heterocycles having biphenylsulfonyl substitution, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them.
    Type: Application
    Filed: October 30, 2001
    Publication date: April 18, 2002
    Inventors: Heinz-Werner Kleemann, Hans Jochen Lang, Jan-Robert Schwark, Andreas Weichert, Sabine Faber, Hans-Willi Jansen
  • Biphenylsulfonyl-substituted imidazole derivatives, their preparation process, their use as a drug or diagnostic agent and drug containing them
    Patent number: 6372917
    Abstract: The invention relates to compounds of formula (I), wherein the symbols have the meanings indicated in the specification. The inventive compounds exhibit dramatic antiarrhythmic proprieties and contain a cardioprotective compound. They can preventively inhibit or strongly reduce pathophysiologic processes upon occurrence of ischemic injuries, especially ischemic cardiac arrhythmia. Said compounds also exhibit a strong inhibiting effect on cellular proliferation.
    Type: Grant
    Filed: January 17, 2001
    Date of Patent: April 16, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Heinz-Werner Kleemann, Hans Jochen Lang, Jan-Robert Schwark, Andreas Weichert, Stefan Petry
  • Biphenylsulfonyl cyanamides, method for the production thereof and their utilization as a medicament
    Patent number: 6369069
    Abstract: The invention relates to compounds of the formula (I), in which the symbols have the following meaning: R(1) is 1. alkyl having 1, 2, 3, 4, 5, 6, 7 or 8 carbon atoms; 2. alkyl having 1, 2, 3, 4, 5, 6, 7 or 8 carbon atoms, in which one to all hydrogen atoms are replaced by fluorine; 3. alkenyl having 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12 carbon atoms; or 4. —CnH2n−nn—Y, nn is zero or 2; and n is zero, 1, 2, 3 or 4; where n is unequal to zero or 1 if nn is equal to 2; 5. —CnH2n−nn—Y, nn is zero or 2; and n is 1, 2, 3 or 4; where n is unequal to 1 if nn is equal to 2.
    Type: Grant
    Filed: August 4, 2000
    Date of Patent: April 9, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Heinz-Werner Kleemann, Hans-Jochen Lang, Jan-Robert Schwark, Andreas Weichert, Sabine Faber, Hans-Willi Jansen, Stefan Petry
  • Imidazole derivatives with biphenylsulfonyl substitution method for preparing them and their use as a drug or diagnostic agent
    Patent number: 6369236
    Abstract: The invention relates to compounds of formula (I), wherein the symbols have the meanings indicated in the specification. The inventive compounds exhibit dramatic antiarrhythmic proprieties and contain a cardioprotective compound. They can preventively inhibit or strongly reduce pathophysiologic processes upon occurrence of ischemic injuries, especially ischemic cardiac arrhythmia. Said compounds also exhibit a strong inhibiting effect on cellular proliferation.
    Type: Grant
    Filed: January 18, 2001
    Date of Patent: April 9, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Heinz-Werner Kleemann, Hans Jochen Lang, Jan-Robert Schwark, Stefan Petry, Andreas Weichert
  • 8,8A-DIHYDROINDENO[1,2-D]THIAZOLE DERIVATIVES WHICH CARRY IN THE 2-POSITION A SUBSTITUENT HAVING A SULFONAMIDE STRUCTURE OR SULFONE STRUCTURE; PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
    Patent number: 6352987
    Abstract: 8,8a-Dihydroindeno[1,2-d]thiazole derivatives which carry in the 2-position a substituent having a sulfonamide structure or sulfone structure; processes for their preparation and their use as medicaments The invention relates to polycyclic dihydrothiazoles and to their physiologically acceptable salts and physiologically functional derivatives. Compounds of formula I, in which the radicals are as defined above, and their physiologically acceptable salts and processes for their preparation are described. The compounds are suitable, for example, as anorectics.
    Type: Grant
    Filed: February 26, 2001
    Date of Patent: March 5, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Gerhard Jaehne, Hans Jochen Lang, Matthias Gossel, Martin Bickel
  • Five-membered heterocycles having biphenylsulfonyl substitution, with sulfonylcyanamide side chain, compositions containing them, and methods of using them
    Patent number: 6335451
    Abstract: Five-membered heterocycles having biphenylsulfonyl substitution, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them. Compounds of the formula I in which the symbols have the meanings indicated in the claims, have outstanding antiarrhythmic properties and exhibit a cardioprotective component. They can preventively inhibit or greatly decrease the pathophysiological processes in the formation of ischemically induced damage, in particular in the elicitation of ischemically induced cardiac arrhythmias. Moreover, they have a potent inhibitory action on the proliferation of cells.
    Type: Grant
    Filed: January 21, 1998
    Date of Patent: January 1, 2002
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz-Werner Kleemann, Hans Jochen Lang, Jan-Robert Schwark, Andreas Weichert, Sabine Faber, Hans-Willi Jansen
  • Use of inhibitors of the KQTI channel and methods of controlling and treating diseases caused by helminths and ectoparasites
    Patent number: 6335363
    Abstract: Use of inhibitors of the KQT1 channel for preparing a medicament for treating diseases caused by helminths and ectoparasites Inhibitors of the KQT1 channel are a novel way of destroying helminths and ectoparasites. For this reason, blockers of the cellular KQT1 channel, which is present in helminths and ectoparasites, are used for preparing a medicament for the treatment of vertebrates and humans infested by helminths or ectoparasites. These KQT1 blockers are used as medicaments on their own or in combination with other medicaments and therapeutic measures. Inhibitors of the KQT1 channel are likewise a novel mechanism of action for phytoparasites such as insects, arachnids, molluscs and nematodes, and consequently, they are used for preparing a crop protection composition.
    Type: Grant
    Filed: December 16, 1999
    Date of Patent: January 1, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Uwe Gerlach, Joachim Hofmann, Hans Jochen Lang, Aguan Wei
  • Sulfonamide-substituted fused 7-membered ring compounds, their use as a medicament, and pharmaceutical preparations comprising them
    Patent number: 6333349
    Abstract: The present invention relates to compounds of formula I, in which X1, X2, X3, X4, Y1, Y2, Y3, Y4, R(3), R(4) and R(5) have the meanings mentioned in the specification, their preparation and their use, in particular in pharmaceuticals. The compounds effect the potassium channel or the IKs channel opened by cyclic adenosine monophosphate (cAMP) and are outstandingly suitable as pharmaceutical active compounds, for example for the prophylaxis and therapy of cardiovascular disorders, in particular arrhythmias, for the treatment of ulcers of the gastrointestinal region or for the treatment of diarrheal disorders.
    Type: Grant
    Filed: June 29, 1999
    Date of Patent: December 25, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Joachim Brendel, Hans Jochen Lang, Uwe Gerlach
  • Use of polycyclic thiazole systems for the treatment of obesity
    Patent number: 6329407
    Abstract: The invention relates to the use of polycyclic thiazole systems and their physiologically tolerated salts and physiologically functional derivatives for the treatment of obesity. The treatment involves administration of a compound of formula I, in which the radicals have the stated meanings, and of their physiologically tolerated salts and physiologically functional derivatives.
    Type: Grant
    Filed: February 9, 2000
    Date of Patent: December 11, 2001
    Assignee: AventisPharma Deutschland GmbH
    Inventors: Gerhard Jähne, Karl Geisen, Hans-Jochen Lang, Martin Bickel
  • Heterocyclically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics, and medicaments comprising them
    Publication number: 20010049446
    Abstract: Heterocyclically substituted benzoylguanidines of the formula I 1
    Type: Application
    Filed: July 11, 2001
    Publication date: December 6, 2001
    Inventors: Andreas Weichert, Udo Albus, Hans-Willi Jansen, Heinz-Werner Kleemann, Hans-Jochen Lang
  • 8,8a-dihydroindeno[1,2-d]thiazole derivatives which carry in the 2-position a substituent having a sulfonamide structure or sulfone structure; processes for their preparation and their use as medicaments
    Publication number: 20010039278
    Abstract: 8,8a-Dihydroindeno[1,2-d]thiazole derivatives which carry in the 2-position a substituent having a sulfonamide structure or sulfone structure; processes for their preparation and their use as medicaments
    Type: Application
    Filed: February 26, 2001
    Publication date: November 8, 2001
    Inventors: Gerhard Jaehne, Hans Jochen Lang, Matthias Gossel, Martin Bickel
  • Substituted 8,8a-dihydro-3ah-indeno[1,2-d]thiazoles, processes for their preparation and their use as medicaments
    Publication number: 20010031752
    Abstract: The invention relates to substituted 8,8a-dihydro-3aH-indeno[1,2-d]thiazoles and to their physiologically acceptable salts and physiologically functional derivatives.
    Type: Application
    Filed: February 23, 2001
    Publication date: October 18, 2001
    Inventors: Gerhard Jaehne, Hans-Jochen Lang, Matthias Gossel, Martin Bickel
  • Substituted norbornylamino derivatives, processes for their preparation, their use as medicaments or diagnostics, and a medicament comprising them
    Publication number: 20010023257
    Abstract: The application discloses substituted norbornylamino derivatives, processes for their preparation, their use as medicaments or diagnostics and a medicament comprising them
    Type: Application
    Filed: December 12, 2000
    Publication date: September 20, 2001
    Inventors: Uwe Heinelt, Hans-Jochen Lang, Heinz-Werner Kleemann, Jan-Robert Schwark, Klaus Wirth, Hans-Willi Jansen
  • Polycyclic thiazol-2-ylidene amines, processes for their preparation and their use as medicaments
    Patent number: 6288094
    Abstract: The invention relates to polycyclic thiazolidin-2-ylidene amines and their physiologically tolerated salts and physiologically functional derivatives. Polycyclic thiazolidin-2-ylidene amines of the formula I, in which the radicals have the stated meanings, and their physiologically tolerated salts and processes for their preparation are described. The compounds are suitable, for example as anorectics and in the treatment or prophylaxis of type II diabetes.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: September 11, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Gerhard Jähne, Karl Geisen, Hans-Jochen Lang, Martin Bickel