Patents by Inventor Haralambos Gavras

Haralambos Gavras has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5567706
    Abstract: A method of treating impotency in men using a pharmaceutical composition having an effective amount for treating impotency of a selective post-synaptic peripheral .alpha..sub.1 -adrenoceptor antagonist having antihypertensive characteristics, and yohimbine, a central and peripheral .alpha..sub.2 -adrenoceptor inhibitor and parasympathetic agonist.
    Type: Grant
    Filed: August 2, 1994
    Date of Patent: October 22, 1996
    Inventor: Haralambos Gavras
  • Patent number: 5070187
    Abstract: A unique class of vasopressin analogue antagonists is provided which have the pharmacological property in-vivo to antagonize pressor (V.sub.1) and/or antidiuretic (V.sub.2) activities. The chemical modifications to the vasopressin 9 member chain sequence at the no. 1, 2, and 4 positions yield a class of potent analogue antagonists which may be employed therapeutically to treat hypertension, congestive heart failure, various edematous situations, and a variety of symptoms due to inappropriate vasopressin secretion.
    Type: Grant
    Filed: November 3, 1989
    Date of Patent: December 3, 1991
    Assignee: Trustees of Boston University
    Inventors: Haralambos Gavras, Bernard Lammek
  • Patent number: 4778787
    Abstract: Angiogenesis healing factors residing in omentum-derived lipid fractions with or without gangliosides or their synthetic equivalents can be used to treat myocardial ischemic conditions including but not limited to myocardial infarction, angina, as well as in heart transplant, vascular grafts, and re-opened vessels leading to improved vascularization, perfusion, collagenization and organization of said lesions; the involved and adjacent tissues.
    Type: Grant
    Filed: December 20, 1985
    Date of Patent: October 18, 1988
    Assignees: Trustees of Boston University, Angio-Medical Corporation
    Inventors: Nicholas Catsimpoolas, Haralambos Gavras, Christian C. Haudenschild, Michael I. Klibaner
  • Patent number: 4762820
    Abstract: A novel therapeutic method for treating human and animal subjects afflicted with congestive heart failure is provided by administering effective dosages of a selective antagonist for arginine vasopressin to the subject. The antagonist is an effective and potent inhibitor for vasopressin and is a therapeutic agent selected from the class consisting of analogues of previously prepared compositions synthesized in a conventionally known manner. The administration of such selective antagonist as a therapeutic agent results in a demonstrated beneficial change in approximately thirty percent of tested individuals.
    Type: Grant
    Filed: March 3, 1986
    Date of Patent: August 9, 1988
    Assignee: Trustees of Boston University
    Inventor: Haralambos Gavras