Patents by Inventor Harald Furrer

Harald Furrer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5922868
    Abstract: Use of xanthine derivatives for the treatment of nerve damage following an interruption in blood circulation.The invention relates to the use of xanthine derivatives of the formula I ##STR1## in which R.sup.2 is a (C.sub.1 -C.sub.4)-alkyl group and at least one of the symbols R.sup.1 and R.sup.3 is a radical of the formula II or III ##STR2## in which A is CHOH, CO or dioxolane, R.sup.4 is a hydrogen atom or a (C.sub.1 -C.sub.4)-alkyl group and n is 0 to 5, and in which R.sup.5 and R.sup.6 are hydrogen atoms or (C.sub.1 -C.sub.4)-alkyl groups or, together with the nitrogen atom to which they are bonded, form a 5- to 7-membered ring, it being possible for one carbon atom to be replaced by an oxygen or nitrogen atom, m is 1 or 2 and the other radical R.sup.1 or R.sup.3, if appropriate, is a hydrogen atom, a (C.sub.1 -C.sub.6)-alkyl group or a (C.sub.3 -C.sub.
    Type: Grant
    Filed: December 22, 1995
    Date of Patent: July 13, 1999
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Werner Thorwart, Harald Furrer, Erhard Wolf, Ulrich Gebert, Erhard Rossmanith, John J. Grome, Ernst-Jurgen Schneider
  • Patent number: 5710272
    Abstract: A Rhodotorula rubra strain has been found which reduces pentoxifylline to 100% to give the S-alcohol. Moreover, other oxoalkylxanthine derivatives can also be convened into the corresponding S-alcohol. The microbiologically obtained S-(+)-enantiomers can then be converted stereoselectively into the respective R-(-)-enantiomers. The corresponding S-alcohols and the R-alcohols obtained by enantioselective inversion of configuration cause an increase in cerebral blood flow.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 20, 1998
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Werner Aretz, Harald Furrer, Ulrich Gebert, Heinz-Joachim Hinze
  • Patent number: 5556854
    Abstract: Pyridopyrimidinediones, processes for their preparation and their use as drugsA compound of the formula I: ##STR1## and/or physiologically acceptable salts of the compound of the formula I, and/or optionally stereoisomeric forms of the compound of the formula I, are suitable for the preparation of drugs for the treatment of circulatory disorders and/or neurodegenerative diseases.
    Type: Grant
    Filed: April 21, 1994
    Date of Patent: September 17, 1996
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Harald Furrer, Dirk Seiffge, Ismahan Okyayuz-Baklouti, John J. Grome
  • Patent number: 5478831
    Abstract: R-(-)-1-(5-Hydroxyhexyl)-3-methyl-7-propylxanthine, a process for its preparation, and pharmaceuticals which contain this compound and which are suitable, in particular, for the prophylaxis and treatment of cerebral vascular disorders.
    Type: Grant
    Filed: May 12, 1994
    Date of Patent: December 26, 1995
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Harald Furrer, Ulrich Gebert, Karl Rudolphi
  • Patent number: 5472873
    Abstract: A Rhodotorula rubra strain has been found which reduces pentoxifylline to 100% to give the S-alcohol. Moreover, other oxoalkylxanthine derivatives can also be converted into the corresponding S-alcohol. The microbiologically obtained S-(+)-enantiomers can then be converted stereo-selectively into the respective R-(-)-enantiomers. The corresponding S-alcohols and the R-alcohols obtained by enantioselective inversion of configuration cause an increase in cerebral blood flow.
    Type: Grant
    Filed: February 10, 1994
    Date of Patent: December 5, 1995
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Werner Aretz, Harald Furrer, Ulrich Gebert, Heinz-Joachim Hinze
  • Patent number: 5407815
    Abstract: R-(-)-1-(5-Hydroxyhexyl)-3-methyl-7-propylxanthine, a process for its preparation, and pharmaceuticals which contain this compound and which are suitable, in particular, for the prophylaxis and treatment of cerebral vascular disorders.
    Type: Grant
    Filed: December 21, 1990
    Date of Patent: April 18, 1995
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Harald Furrer, Ulrich Gebert, Karl Rudolphi
  • Patent number: 5310666
    Abstract: A Rhodotorula rubra strain has been found which reduces pentoxifylline to 100% to give the S-alcohol. Moreover, other oxoalkylxanthine derivatives can also be converted into the corresponding S-alcohol. The microbiologically obtained S-(+)-enantiomers can then be converted stereoselectively into the respective R-(-)-enantiomers. The corresponding S-alcohols and the R-alcohols obtained by enantioselective inversion of configuration cause an increase in cerebral blood flow.
    Type: Grant
    Filed: November 13, 1992
    Date of Patent: May 10, 1994
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Werner Aretz, Harald Furrer, Ulrich Gebert, Heinz-Joachim Hinze
  • Patent number: 5082845
    Abstract: Therapeutic agents for the treatment of peptic ulcer disease, containing as active ingredient, at least one compound of the general formula ##STR1## wherein R.sup.1 and R.sup.3 are the same or different and are each (C.sub.1 -C.sub.8)alkyl, ##STR2## R.sup.2 is (C.sub.1 -C.sub.4)alkyl; R.sup.4 and R.sup.5 are the same or different and are each hydrogen or (C.sub.1 -C.sub.2)alkyl; R.sup.6 is (C.sub.1 -C.sub.2)alkyl; and m, n and p are the same or different and are each 1, 2, 3, 4, 5 or 6; with the proviso that one of the groups R.sup.1 and R.sup.3 is ##STR3## or that R.sup.3 represents ##STR4## Some of the compounds of formula I are novel.
    Type: Grant
    Filed: February 17, 1989
    Date of Patent: January 21, 1992
    Assignee: Hoechst Japan Limited
    Inventors: Erhard Wolf, Ulrich Gebert, Harald Furrer, Toshizo Tanaka, Masao Sakurai, Masayoshi Goto
  • Patent number: 4713455
    Abstract: Compounds of the formula ##STR1## wherein one of the radicals R.sup.1, R.sup.2 or R.sup.3 denotes a straight-chain alkyl group having 4 to 8 C atoms and two vicinal hydroxyl groups in the .omega.,.omega.-1 or .omega.-1,.omega.-2 positions and the two other radicals represent straight-chain or branched alkyl groups having up to 12 C atoms in the position of R.sup.1 and R.sup.3 and up to 4 C atoms in the position of R.sup.2, the total of C atoms in these two alkyl substituents being a maximum of 14, are prepared by oxidation of the corresponding alkenylxanthines and by alkylation with compounds which introduce the dihydroxyalkyl radical or a precursor thereof. The dihydroxyalkyldialkylxanthines are suitable for the treatment of obstructive respiratory tract diseases.
    Type: Grant
    Filed: April 4, 1986
    Date of Patent: December 15, 1987
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Harald Furrer, Hiristo Anagnostopulos, Ulrich Gebert
  • Patent number: 4616020
    Abstract: Compounds of the formula ##STR1## wherein one of the radicals R.sup.1, R.sup.2 or R.sup.3 denotes a straight-chain alkyl group having 4 to 8 C atoms and two vicinal hydroxyl groups in the .omega.,.omega.-1 or .omega.-1,.omega.-2 positions and the two other radicals represent straight-chain or branched alkyl groups having up to 12 C atoms in the position of R.sup.1 and R.sup.3 and up to 4 C atoms in the position of R.sup.2, the total of C atoms in these two alkyl substituents being a maximum of 14, are prepared by oxidation of the corresponding alkenylxanthines and by alkylation with compounds which introduce the dihydroxyalkyl radical or a precursor thereof. The dihydroxyalkyldialkylxanthines are suitable for the treatment of obstructive respiratory tract diseases.
    Type: Grant
    Filed: September 17, 1982
    Date of Patent: October 7, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Harald Furrer, Hiristo Anagnostopulos, Ulrich Gebert, Heinz-Joachim Hinze
  • Patent number: 4207321
    Abstract: A pharmaceutical composition having as an essential ingredient a compound of the formula ##STR1## wherein one to three of R.sup.1, R.sup.2 and R.sup.3 represent an alkenyl group having from 4 to 8 carbon atoms, the other ones are alkyl having from 1 to 12 carbon atoms, and R.sup.1 may also be hydrogen, the compounds themselves and a process for preparing them.
    Type: Grant
    Filed: October 2, 1978
    Date of Patent: June 10, 1980
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Harald Furrer, Alfons Soder, Jaromir Komarek, Heinz-Joachim Hinze, Gerhard Munch
  • Patent number: 4159202
    Abstract: This invention relates to a photo-cross-linkable polymer containing units each having a 2-pyridone side group. The invention also relates to a photosensitive copying material including the novel photo-cross-linkable polymer.
    Type: Grant
    Filed: May 26, 1977
    Date of Patent: June 26, 1979
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Harald Furrer, Hartmut Steppan, Gerhard Lohaus
  • Patent number: 3969323
    Abstract: This invention relates to a photo-crosslinkable polymer comprising units with side chains having 2-pyrone groups therein. The invention also relates to processes for the preparation of the novel photo-crosslinkable polymers and to a photo-curable copying composition including the photo-crosslinkable polymer.
    Type: Grant
    Filed: February 26, 1974
    Date of Patent: July 13, 1976
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Harald Furrer, Hartmut Steppan, Gerhard Lohaus